Exosomes (EVs) are extracellular phospholipid bilayer vesicles with a diameter of 30 to 150 nm. It is reported that many types of cells, tissues and biological fluids can secrete exosomes, including blood, urine, milk, tears and cerebrospinal fluid. Breast milk is an irreplaceable nutrition for...

Polycystic ovary syndrome (PCOS) is a disease characterized by metabolic disorders. This study aimed to examine the effects of resveratrol treatment on ovulation in the PCOS rat model. Quantitative real-time PCR and immunohistochemistry were used to determine the mRNA and protein expression levels. ...

Objective To observe the effect of YNS skin-nourishing cream for the improvement and repair of damaged skin and its influence on the intestinal flora of guinea pigs. Methods Twenty-four guinea pigs were randomly divided into four groups: Control group, Positive control group, Cosmetic group and...

Advanced glycation end products (AGEs) are a series of stable compounds generated by the nonenzymatic reaction of reducing sugars with proteins, lipids or nucleic acids. It has been found that the excessive accumulation of AGEs in the body can easily cause various chronic diseases such as diabetes, ...

Nootropics (smart drugs) are used by students to enhance cognitive performance which have been reported times in recent years. However, some of the nootropics are central nervous system stimulants which are very likely to lead to addiction or complications such as vomiting and dizziness. Are there...

A sensitive and rapid ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was hereby developed for the determination of seven components, namely, glycyrrhizic acid, glycyrrhetinic acid, dehydrotumulosic acid, isoliquiritin, liquiritin, atractylenolide III, and...

The present study aimed to investigate the role of tea polyphenols (TP) playing in glucose metabolism in male ceruloplasmin knockout mice (CP^-/-), an iron-overloaded model. Compared to wild-type CP^+/+ mice, CP^-/- mice exhibited hyperglycemia, insulin resistance and excess iron deposition in liver...

Certain antimicrobial preservatives (APs) have been shown to perturb gut microbiota. So far, it is not yet fully known that whether similar effects are observable for a more diverse set of APs. It also remains elusive if biogenic APs are superior to synthetic APs in terms of safety. To help fill...

Fifteen previously undescribed minor iridoid glycosides, including four monomers and eleven dimers, were isolated from the fruits of Cornus officinalis Sieb. et Zucc. Their chemical structures were determined on the basis of spectroscopic data and chemical evidence. All of the isolated compounds...

Interactions between diet and the intestinal microbiome play an important role in human health and disease development. It is well known that such interactions, whether direct or indirect, trigger a series of metabolic reactions in the body. Evidence suggests that intestinal stem cells (ISCs),...