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Abstract

The genetic backgrounds of 24 enterotoxigenic Escherichia coli (ETEC) strains from Mexico and Guatemala expressing heat-stable toxin (ST) and coli surface antigen 6 (CS6) were analyzed. US travelers to these countries and resident children in Guatemala were infected by ETEC strains of sequence type ...

Author(s)
Nicklasson, M.; Klena, J.; Rodas, C.; Bourgeois, A. L.; Torres, O.; Svennerholm, A. M.; Sjöling, Ǻ.
Publisher
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, USA
Citation
Emerging Infectious Diseases, 2010, 16, 1, pp 143-146
Abstract

We tested the efficacy of a killed oral vaccine for enterotoxigenic Escherichia coli (ETEC) diarrhoea to determine if two doses of vaccine with colonization factor antigens (CF) and cholera B subunit would protect against ETEC diarrhoea of travellers. Six hundred seventy-two healthy travellers...

Author(s)
Sack, D. A.; Shimko, J.; Torres, O.; Bourgeois, A. L.; Sanchez Francia, D.; Gustafsson, B.; Kärnell, A.; Nyquist, I.; Svennerholm, A. M.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Vaccine, 2007, 25, 22, pp 4392-4400
Abstract

Background: Enterotoxigenic Escherichia coli (ETEC) is a major cause of travellers' diarrhoea. We investigated the rate of diarrhoea attacks, safety, and feasibility of a vaccine containing heat-labile enterotoxin (LT) from ETEC delivered to the skin by patch in travellers to Mexico and Guatemala....

Author(s)
Frech, S. A.; DuPont, H. L.; Bourgeois, A. L.; McKenzie, R.; Belkind-Gerson, J.; Figueroa, J. F.; Okhuysen, P. C.; Guerrero, N. H.; Martinez-Sandoval, F. G.; Meléndez-Romero, J. H. M.; Jiang, Z. D.; Asturias, E. J.; Halpern, J.; Torres, O. R.; Hoffman, A. S.; Villar, C. P.; Kassem, R. N.; Flyer, D. C.; Andersen, B. H.; Kazempour, K.; Breisch, S. A.; Glenn, G. M.
Publisher
Elsevier Ltd, London, UK
Citation
Lancet (British edition), 2008, 371, 9629, pp 2019-2025