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Abstract

Background: Artemisinin-based combination therapy (ACT) is the global standard of care for uncomplicated falciparum malaria. First reports of ACT resistance came from western Cambodia and the Thailand-Cambodia border in 2002-2004. The subsequent emergence and expansion of Plasmodium falciparum...

Author(s)
Müller, O.; Lu GuangYu; Seidlein, L. von
Publisher
Oxford University Press, Cary, USA
Citation
Journal of Travel Medicine, 2019, 26, 4, pp taz030
Abstract

Background: Schistosoma mekongi is one of five major causative agents of human schistosomiasis and is endemic to communities along the Mekong River in southern Lao People's Democratic Republic (Laos) and northern Cambodia. Sporadic cases of schistosomiasis have been reported in travelers and...

Author(s)
Phuphisut, O.; Ajawatanawong, P.; Limpanont, Y.; Reamtong, O.; Nuamtanong, S.; Ampawong, S.; Chaimon, S.; Dekumyoy, P.; Watthanakulpanich, D.; Swierczewski, B. E.; Adisakwattana, P.
Publisher
BioMed Central Ltd, London, UK
Citation
Parasites and Vectors, 2018, 11, 504, pp (10 September 2018)
Abstract

Successful control of falciparum malaria depends greatly on treatment with artemisinin combination therapies. Thus, reports that resistance to artemisinins (ARTs) has emerged, and that the prevalence of this resistance is increasing, are alarming. ART resistance has recently been linked to...

Author(s)
Dogovski, C.; Xie, S. C.; Burgio, G.; Bridgford, J.; Mok, S.; McCaw, J. M.; Chotivanich, K.; Kenny, S.; Gnädig, N.; Straimer, J.; Bozdech, Z.; Fidock, D. A.; Simpson, J. A.; Dondorp, A. M.; Foote, S.; Klonis, N.; Tilley, L.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS Biology, 2015, 13, 4, pp e1002132
Abstract

Malaria still poses a real threat to travellers, particularly in areas with high transmission rates such as sub-Saharan Africa, Papua New Guinea, and the South Pacific islands. Malaria causes an estimated 660,000 deaths each year from 219 million cases of illness. It is a preventable and curable...

Author(s)
López del Prado, G. R.; Hernán García, C.; Moreno Cea, L.; Fernández Espinilla, V.; Muñoz Moreno, M. F.; Delgado Márquez, A.; Polo Polo, M. J.; Andrés García, I.
Publisher
Open Learning on Enteric Pathogens (OLOEP), Sassari, Italy
Citation
Journal of Infection in Developing Countries, 2014, 8, 1, pp 1-4
Abstract

The recent detection of clinical Artemisinin (ART) resistance manifested as delayed parasite clearance in the Cambodia-Thailand border area raises a serious concern. The mechanism of ART resistance is not clear; but the P. falciparum sarco/endoplasmic reticulum Ca2+-ATPase (PfSERCA or PfATP6) has...

Author(s)
Miao, M.; Wang, Z. L.; Yang ZhaoQing; Yuan LiLi; Parker, D. M.; Putaporntip, C.; Jongwutiwes, S.; Xangsayarath, P.; Pongvongsa, T.; Moji, H.; Trinh Dinh Tuong; Abe, T.; Nakazawa, S.; Myat Phone Kyaw; Yan, G. Y.; Sirichaisinthop, J.; Sattabongkot, J.; Mu, J. B.; Su, X. Z.; Kaneko, O.; Cui, L. W.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2013, 8, 3, pp e59192
Abstract

There is growing evidence that Plasmodium falciparum parasites in southeastern Asia have developed resistance to artemisinin combination therapy. The resistance phenotype has recently been shown to be associated with four single nucleotide polymorphisms in the parasite's genome. We assessed the...

Author(s)
Hunja, C. W.; Unger, H.; Ferreira, P. E.; Lumsden, R.; Morris, S.; Aman, R.; Alexander, C.; Mita, T.; Culleton, R.
Publisher
Elsevier Ltd, Oxford, UK
Citation
International Journal for Parasitology, 2013, 43, 11, pp 885-889
Abstract

Human opisthorchiasis caused by the liver fluke Opisthorchis viverrini is an endemic disease in Southeast Asian countries including the Lao People's Democratic Republic, Cambodia, Vietnam, and Thailand. Infection with the soil-transmitted roundworm Strongyloides stercoralis is an important problem...

Author(s)
Janwan, P.; Intapan, P. M.; Thanchomnang, T.; Lulitanond, V.; Anamnart, W.; Maleewong, W.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Parasitology Research, 2011, 109, 6, pp 1593-1601
Abstract

Background: The presence of ongoing local malaria transmission, identified though local surveillance and reported to regional WHO offices, by S-E Asian countries, forms the basis of national or international chemoprophylaxis recommendations in western countries. The study was designed to examine...

Author(s)
Behrens, R. H.; Carroll, B.; Hellgren, U.; Visser, L. G.; Siikamaki, H.; Vestergaard, L. S.; Calleri, G.; Janisch, T.; Myrvang, B.; Gascon, J.; Hatz, C.
Publisher
BioMed Central Ltd, London, UK
Citation
Malaria Journal, 2010, 9, 266, pp (4 October 2010)
Abstract

Schistosomiasis found in communities along the Mekong River in Cambodia and Lao People's Democratic Republic (Lao PDR) is caused by the blood fluke Schistosoma mekongi. Early observations on patients in 1957 revealed severe intestinal and hepatosplenic disease. High mortality rates and widespread...

Author(s)
Muth, S.; Sayasone, S.; Odermatt-Biays, S.; Phompida, S.; Duong, S.; Odermatt, P.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Advances in Parasitology, 2010, 72, pp 179-203
Abstract

A 19-year-old woman was given doxycycline (100 mg/day) for malaria prophylaxis before travelling from France to a rural area in Cambodia, between July and December 2001. Six weeks after she returned and 2 weeks after she stopped taking the drug, she visited a doctor for pain in 6 toenails and right ...

Author(s)
Rabar, D.; Combemale, P.; Peyron, F.
Publisher
B. C. Decker Inc., Hamilton, Canada
Citation
Journal of Travel Medicine, 2004, 11, 6, pp 386-387

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