anaplasmosis

Identity

Preferred Scientific Name

• anaplasmosis

International Common Names

• English: anaplasma bovis in cattle - exotic; anaplasmosis in ruminants; anaplasmosis in ruminants, anaplasma marginale, centrale, ovis; gall sickness; gallsickness

Local Common Names

• Australia: tick fever
• Portugal: tristeza

Pathogen/s

Overview

Anaplasmosis is a disease of ruminants caused by obligate intraerythrocytic parasites of the order Rickettsiales, family Anaplasmataceae (Ristic and Kreier, 1984). Cattle, sheep, goats, deer, antelope, giraffes and buffalo may be infected. Anaplasma marginale is the causative agent in cattle and wild ruminants and Anaplasma ovis in sheep and goats.

Anaplasma centrale causes mild anaplasmosis in cattle and was originally isolated in Africa, but is now widely used as an immunizing agent for cattle (Theiler, 1912). Appendages associated with the Anaplasma body have been observed in certain isolates (Kreier and Ristic, 1963) and this parasite has been named Anaplasma caudatum, but its status as a valid species is questionable. Anaplasma mesaeterum is closely related to A ovis and may also cause disease in sheep and goats, however it appears to be less pathogenic for goats (Uilenberg et al., 1979; Nakamura et al., 1993).

Despite widespread distribution and severe losses, effective control of anaplasmosis has not been achieved on a sustainable basis in most affected areas.

Bovine anaplasmosis is on the list of diseases notifiable to the World Organisation for Animal Health (OIE). For information on this disease from OIE, see the website: www.oie.int.

Host Animals

Hosts/Species Affected

Use of Bos indicus cattle as a means of controlling cattle ticks and tick borne diseases has been advocated for many years. The evidence on the relative susceptibility of Bos taurus and Bos indicus cattle to infection by A. marginale is complicated by variation in resistance of individuals within breeds of both species (Callow, 1984).

Some studies (Parker et al., 1985; Bock et al., 1997) found Bos indicus cattle to be marginally more resistant to disease than Bos taurus cattle. However others have reported no difference in susceptibility to A. marginale of Bos taurus and Bos indicus crossbred cattle (½ to ¾ Bos indicus) (Otim et al., 1980; Wilson et al., 1980) or Bos indicus and Bos indicus crossbred cattle (Bock et al., 1999). It is apparent that A. marginale can be a significant cause of disease in any breed, but the resistance of Bos indicus cattle to the tick vectors could reduce the rate of transmission in some circumstances.

Calves from immune mothers receive partial protection from the colostral-derived antibody (Corrier and Guzman, 1977). This protection lasts about 3 months and, in most cases, is followed by an age resistance, which lasts until the animals are about 9 to 12 months old (Jones et al., 1968; Paull et al., 1980). Calves exposed to anaplasmosis when the maternal or age resistance is high, rarely show clinical symptoms but develop a solid, long-lasting immunity. It is therefore possible to have both A. marginale and vectors present on a property without animal losses or clinical disease. This situation is known as endemic stability.

If cattle are not exposed to A. marginale as calves, the age resistance gradually wanes and these animals will become increasingly susceptible to the disease. If these susceptible adult cattle are mixed with infected cattle in the presence of a vector, serious losses due to anaplasmosis can occur.

Cattle that recover from anaplasmosis remain persistent carriers of the organism and are usually immune to further disease particularly from homologous challenge. Persistent infections are characterized by sequential rickettsaemic cycles occurring at 6 to 8 week intervals and this is fundamental to continued reinfection of vectors and thus transmission (Palmer et al., 1999).

Unlike the situation in bovine anaplasmosis, there appears to be no marked age susceptibility to A ovis infection in sheep and goats. Both young and adult animals usually develop only a mild form of the disease although various stress factors can exacerbate this in individual cases (Stoltsz, 1994).

Immune-compromized animals whether by splenectomy or treatment with immunosuppressants, such as cyclophosphamide and corticosteroids, have been shown experimentally to be susceptible to heterologous challenge (Kuttler et al., 1984). It has also been suggested that the immunity of cattle could be compromised under conditions of environmental stress or other stressors (Kuttler et al., 1984), however, Wilson (Wilson, 1979) showed that cattle on a good plane of nutrition developed more severe primary Anaplasma reactions than ones on a starvation ration.

Mixing cattle from different regions, migration of wildlife carriers and seasonal increases in vector activity can also facilitate transmission especially in temperate climates.

Systems Affected

Distribution

Anaplasmosis occurs in tropical and subtropical regions worldwide (approximately 40^o N to 32^o S), including South and Central America, the USA, southern Europe, Africa, Asia and Australia. It is transmitted by a diverse group of biological and mechanical vectors and is endemic in tropical and subtropical areas that support these vectors, with sporadic distribution in temperate climate areas.

Anaplasmosis was reported to AU-IBAR by 14 countries in Africa in 2011 (AU-IBAR, 2011). During 2011, 983 outbreaks were recorded involving 872 deaths. The highest number of outbreaks were reported by Zimbabwe (533), followed by Zambia (100) and Kenya (88). The geographical distribution of the disease shows that it was mainly recorded in the southern parts of the continent.

Countries reporting anaplasmosis to AU-IBAR in 2011:

NS=Not specified

Distribution Table

The distribution in this summary table is based on all the information available. When several references are cited, they may give conflicting information on the status. Further details may be available for individual references in the Distribution Table Details section which can be selected by going to Generate Report.

Pathology

Animals that die of anaplasmosis are generally emaciated, very anaemic and jaundiced. Blood is thin and watery and the spleen is enlarged with soft pulp. The liver may be mottled and yellow-orange and the gall bladder is often enlarged and contains thick brown or green bile. The kidneys are congested and there may be myocardial haemorrhages. There are serous effusions in body cavities, pulmonary oedema and often evidence of severe gastrointestinal stasis especially of the rumen, omasum and colon. The omasal contents are dry and impacted, and the colon contains hard, dry, often bile stained faecal balls. The urine is yellow to dark brown due to the presence of bilirubin and there is a variable degree of red marrow hyperplasia in the long bones (Potgieter and Stoltsz, 1994).

Histological changes in parenchymal organs characteristic of anaemic and hypoxic states may be seen in various organs. There is centrilobular degeneration and necrosis of varying intensity in the liver, with distension of the liver canaliculi due to bile stasis. Also varying degrees of degeneration, necrosis and pigmentation of the tubule cells of the kidneys. There is evidence of haemosiderosis and erythrophagocytosis by the reticulo endothelial system (especially the spleen) and the red bone marrow is usually hyperplastic, but in chronic cases may show signs of depletion (Potgieter and Stoltsz, 1994; Stoltsz, 1994).

Diagnosis

History, clinical signs and post-mortem lesions are often suggestive of anaplasmosis, but microscopical identity of the agent in thin blood films stained with either Giemsa or proprietary stains is required for an accurate diagnosis (Wright and Leatch, 1996). To ensure a diagnosis, scrupulously clean, thin blood films on grease free glass slides should be prepared and stained with a batch of stain that does not precipitate out onto the smear during staining (Callow, 1984). A positive result is usually reported as being significant for bovine anaplasmosis if more than 5% of red blood cells are infected, or where the infection is accompanied by marked anaemic changes of the cells. Badly degenerated babesia or theileria parasites can resemble Anaplasma spp. Organ smears are often unsuitable for diagnosis of Anaplasma spp. because small pieces of tissue debris can look like anaplasms.

Erythrocyte count, packed cell volume and haemoglobin values are all severely depressed. Macrocytic anaemia with circulating reticulocytes may be present late in the disease. There is moderate aniscytosis, slight polychromasia, and an increase in unconjugated bilirubin in the serum.

Differential diagnosis

The clinical signs of anaplasmosis are non-specific and laboratory support is needed to confirm a diagnosis.

Cattle

Anaplasmosis is commonly confused with babesiosis, as many of the epidemiological features are similar. Haemoglobinuria is a distinguishing feature of babesiosis, but is not always present in the early stages of Babesia bovis infection.

Anaemia and progressive weight loss are also clinical signs associated with Trypanosoma spp. infections. Trypanosomiasis in Africa (nagana), generally occurs within well defined, tsetse-infested areas (Potgieter and Stoltsz, 1994).

Some forms of theileriosis should be differentiated from anaplasmosis, and are usually associated with enlarged lymph nodes and the microscopic presence of schizonts in lymph node biopsy smears (Potgieter and Stoltsz, 1994).

Anaemia and icterus may be encountered in cattle suffering from leptospirosis, post-parturient haemoglobinuria, chronic copper poisoning and intoxications with Brassica and Allium spp. In these conditions haemoglobinaemia and haemoglobinuria are present. Causes of hepatotoxicity, such as Lantana camara and Microcystis aeruginosa poisoning in which icterus is one of the principal signs, should also be considered (Potgieter and Stoltsz, 1994).

Changes in behaviour, such as aggression are occasionally manifested in anaplasmosis and need to be differentiated from diseases like heartwater, cerebral babesiosis and cerebral theileriosis, rabies as well as conditions such as lead poisoning.

Sheep and Goats

Many of the differential diagnoses listed for cattle also need to be considered for sheep and goats.

Ehlichiosis, eperythrozoonosis and verminosis (eg haemonchosis) need also to be considered and may occur concurrently.

Laboratory Diagnosis

Wright and Leatch (1996) give a review of diagnostic techniques available for anaplasmosis. Chronically infected carriers may be detected with a fair degree of accuracy by serological testing, but most tests fail to distinguish between species.

The complement fixation test is currently the standard international test for detection of carrier animals for movement controls, but it lacks sensitivity. In a comparison of the indirect fluorescent antibody test, card agglutination tests and the complement fixation test, Gonzalez et al. (1978) found the sensitivity to be 97%, 84% and 79%, respectively while the specificity was 90%, 98% and 100%, respectively.

A recombinant MSP-5 competitive inhibition A. marginale ELISA (McGuire et al., 1991; Knowles et al., 1996; Torioni de Echaide et al., 1998) was recently compared with the card agglutination test and the sensitivity was 98.0%, and 98.0%, and the specificity 99.5% and 98.6%, respectively (Molloy et al., 1999). This ELISA is therefore a useful alternative to the card agglutination test, but reagents are expensive and it requires much more sophisticated laboratory facilities than the card agglutination test.

The sub-inoculation of blood from suspected carrier animals into naïve splenectomized animals (Wright and Leatch, 1996) is a very sensitive method to detect carriers, but too expensive for routine use. DNA-based detection methods are being developed but at this stage are restricted to research use (Gale et al., 1996; Wu et al., 1997; Torioni de Echaide et al., 1998).

Immunology of disease

The protective immune mechanism for anaplasma is not fully understood nor is the mechanism for establishment of persistent infection in the face of an immune response. Cattle that have recovered from acute infection or been immunized with vaccines are solidly protected against challenge with the homologous A. marginale strain, but protection against acute rickettsaemia after challenge with heterologous strains is variable and partial (Palmer et al., 1999). Although antibody alone is not sufficient for protection it is proposed that it provides specificity for macrophage phagocytosis of infected erythrocytes (Palmer et al., 1999).

List of Symptoms/Signs

Disease Course

Bovine anaplasmosis

The number of infected erythrocytes doubles every 24 to 48 hours and the infection is patent within 2 to 8 weeks after infection (Richey and Palmer, 1990), the time influenced by the initial challenge dose (Gale et al., 1996). Connell (Connell and Hall, 1972; Connell, 1974) showed that the prepatent period averaged 27 and 44 days following intrastadial and transstadial transmission by B. microplus, respectively. When transmission is iatrogenic or by biting insects, the prepatent period would be expected to be long, because of the usually low infective dose (Ristic, 1968). Davis et al. (1970) put 0.25 ml of A. marginale infected blood under the lower lid of both eyes in four calves, each of which developed a patent, A. marginale infection, which peaked in 40, 69, 78 and 144 days.

Generally, 10 to 30% of erythrocytes are infected at peak parasitaemia although it can be as high as 90%. Extensive erythrophagocytosis in the reticular endothelial system, initiated by parasite induced red blood cell damage, leads to anaemia (Potgieter and Stoltsz, 1994). This also leads to the release of acute phase inflammatory reactants and consequent development of fever (Radostits et al., 1999). In addition, antibodies produced against the infected and altered erythrocytes sensitize them, thus aiding their removal by the reticular endothelial system. The discrepancy between the number of infected erythrocytes and losses of up to 70% of circulating erythrocytes can probably be explained by an auto-immune mechanism whereby normal erythrocytes are also removed (Potgieter and Stoltsz, 1994). Maximum anaemia develops 1 to 6 days after peak parasitaemia and convalescence usually lasts 1 to 2 months.

The severity of symptoms is age related, but acutely affected animals will show rapid loss of weight, transient fever (40 to 41^oC at peak parasitaemia), weakness and respiratory distress, particularly after exercise. There is also depression, loss of appetite and pale mucous membranes (anaemia) followed by jaundice. The urine is often brown due to bile pigments, but not red as in babesiosis. Pregnant cows may abort.

Losses during an outbreak can be as high as 20 to 50%, although a mortality rate of 5 to 10% in newly infected herds is more common. In persistently infected herds, mortalities of 1 to 2% each year are common if control procedures are not instituted.

Ovine anaplasmosis

The pathogenesis of ovine anaplasmosis is very similar to that of bovine anaplasmosis, but parasitaemias are usually lower, reaching 0.1 to 4% in sheep and 1 to 12% in goats (Stoltsz, 1994).

Epidemiology

Vertebrate host

The complete development cycle of A. marginale in the vertebrate host occurs in mature erythrocytes. When infected erythrocytes are disrupted, initial bodies are released to invade other erythrocytes by invagination of their cytoplasmic membranes to form vacuoles containing organisms. The initial bodies then undergoes a series of binary fissions to form structures, known as inclusion bodies, which are made up of between four and eight initial bodies (Ristic, 1981).

Transmission

Anaplasmosis is not contagious and most transmission occurs via ticks with over 20 species being incriminated worldwide as biological vectors (Kocan, 1995). However experimental demonstration of vector competence does not necessarily imply a role in transmission in the field. Any stage of the tick’s life cycle can become infected after feeding on an animal carrying Anaplasma organisms in its blood stream.

After feeding on an infected animal the organism undergoes a complex development cycle in the gut cells of ticks and the final infective stage is present in the salivary glands (Kocan et al., 1992; Kocan et al., 1993). Transmission mainly takes place trans-stadially or intrastadially via interhost transfer of ticks (Potgieter and Stoltsz, 1994). The few reported cases of trans-ovarial transmission by ticks reported in the literature are generally regarded as being exceptional (Potgieter and Stoltsz, 1994). The male tick is more mobile and lives longer than other stages, so it is thought to be the most likely stage to transmit the disease (Stiller and Coan, 1995). Male Dermacentor andersoni can act as effective vectors for at least 120 days (Stiller and Coan, 1995). Because an infected stage of the tick must transfer to a susceptible animal, it is considered necessary to have Anaplasma infected animals in close contact with susceptible animals for transmission to occur.

Transmission by biting dipterans is considered to be important in parts of the USA (Kuttler, 1979), but less important elsewhere (Rogers and Shiels, 1979; Potgieter and Stoltsz, 1994). There appears to be no developmental cycle of Anaplasma spp. in biting dipterans (Roberts and Love, 1977; Foil, 1989). The rickettsia remain viable and infective in arthropods for at least 2 to 3 days after ingestion, but it is believed that successful mechanical transmission can only be achieved where there is minimal time lapse (a few minutes) between consecutive feeds (Potgieter and Stoltsz, 1994).

Trans-placental transmission occurs and is probably underestimated (Zaugg, 1987; Potgieter and Stoltsz, 1994; Barry and Niekerk, 1990). It is usually associated with infection of the dam in the second or third trimester of gestation. Anaplasmosis may also be spread through blood transfer on contaminated needles, dehorning, castration or other surgical instruments (iatrogenic transmission) unless care is taken to clean instruments between use on each animal (Ristic, 1968; Hungerford and Smith, 1997; Abdala et al., 1998).

Impact: Economic

The impact of anaplasmosis on production is affected by the intensity of the production system. Impact is smaller under low input-low output production methods than under more intensive systems. Estimates of total cost are most useful if the disease is eradicable and for most countries where Anaplasma is endemic this is not feasible. When comparing the costs of using/developing a control technique or strategy to expected benefits a number of factors need considering. These include opportunity costs, feasibility, adoption rate, impacts on wider benefits such as lost potential, acaricide resistance, residues, environmental pollution and market effects (Perry and Randolph, 1999). Such wide reaching economic estimates are not available for anaplasmosis so the cost will usually be underestimated.

Anaplasmosis is often associated with other tick borne diseases so one control technique (e.g. use of acaricides) may prevent several diseases. Also fluctuating vector populations can lead to varying levels of natural immunity so the susceptible population is often difficult to estimate. Therefore any form of control in local resistant livestock is not always cost-effective, whereas intensive and expensive control measures are often required for valuable exotic breeds.

In the USA where bovine anaplasmosis costs are not complicated by other haemoparasites the annual loss of 50,000 to 100,000 head of cattle was estimated in 1986 at US $300 million (Palmer, 1989). More specifically, in 1983 it was estimated that the annual cost of treatment and prevention of bovine anaplasmosis, losses in milk production and deaths or culling were valued at US $0.5 million in the Red River Plains and south-east areas of Louisiana (Morley and Hugh-Jones, 1989).

Using a disease prediction-vaccination model (Ramsay, 1997), annual A. centrale vaccination of Bos indicus and Bos indicus cross Bos taurus weaners in a representative beef herd in north west Queensland, Australia was estimated to yield a benefit to cost ratio over 8 years in the range of four to 22 and seven to 39, respectively (Bock et al., 1999). The range depended on the estimated annual seroprevalence of Anaplasma in yearling cattle in the herd.

Zoonoses and Food Safety

Anaplasma spp. poses no known zoonotic or food safety problems.

Disease Treatment

Treatment of anaplasmosis can be with oxytetracycline at 6 to 10 mg/kg body weight daily for 3 to 5 days, or a single injection of long-acting oxytetracycline at a dose of 20 mg/kg intramuscularly (Rogers and Shiels, 1979; Stewart et al., 1979). Imidocarb dipropionate as a single injection at 3mg/kg body weight is also highly efficacious for bovine anaplasmosis and does not interfere with acquired immunity (Vos et al., 1987), but is not approved for use in some countries.

Prompt treatment in the early stages (PCV > 15%) of acute disease usually ensures survival, but severely infected animals may die in spite of treatment. Symptomatic treatments such as blood transfusions, administration of haematonics, tonics and fluids as well as appetite stimulants, rumenotonics and mild laxatives may also be beneficial (Stoltsz, 1994).

Prevention and Control

Immunization and Vaccines

All current vaccines are derived from blood of infected cattle resulting in a high cost of production and difficulties in standardization. There is no vaccine routinely available for ovine anaplasmosis, but if required artificial infection followed by treatment may be useful.

Live vaccines

A. centrale is used in vaccine, prepared from blood of infected splenectomized calves, in Australia (Rogers and Shiels, 1979) South Africa, (Potgieter, 1979) Argentina, (Anziani et al., 1987) Uruguay, (Nari et al., 1979) Israel, (Pipano et al., 1986) and more recently Zimbabwe (Turton et al., 1998) and Malawi (Tjornehoj et al., 1997). The only known vector of A. centrale is the African tick Rhipicephalus simus (Potgieter and van Rensburg, 1987). The protective potential of A. centrale isolates against A. marginale is partial and variable (Kuttler, 1967; Potgieter and van Rensburg, 1983; Anziani et al., 1987; Payne et al., 1990; Brizuela et al., 1998; Turton et al., 1998).

A modified live, A. marginale vaccine of ovine origin (Anavac) is also available, but is currently restricted for use to California only (Ristic et al., 1968; Osorno et al., 1975; Corrier et al., 1980; Vizcaino et al., 1980; Henry et al., 1983).

With these live blood-derived vaccines there is a risk of widespread transmission of unknown or newly emerging pathogens and strict production standards need to be adhered to in order to minimize this (Rogers et al., 1988).

Killed vaccines

A. centrale vaccine cannot be used in the USA, but non-living vaccines purified from infected bovine erythrocytes have been used (Vizcaino et al., 1980; Kuttler et al., 1984; Figueroa Millan et al., 1999), but were withdrawn from the US market in 1998. These vaccines reduced the severity of the disease but may cause neonatal isoerythrolysis in calves from some vaccinated Dams.

An experimental killed vaccine that does not cause neonatal isoerythrolysis in calves may be available in Louisiana, USA from Louisiana State University but is in its experimental stages (Hart et al., 1987; Luther et al., 1990; Luther et al., 1990).

Elimination of carriers

In non-endemic regions, movement controls, serological detection and culling or treating of carriers as well as vector control can be used to ensure freedom from anaplasmosis. Movement of wildlife can complicate such control programs.

The carrier-state has been eliminated by various regimes (Potgieter and Stoltsz, 1994). The administration of three injections of long acting oxytetracycline (20 mg/kg) at 1 week intervals combined with two injections of imidocarb dipropionate at 3mg/kg at a 2 week interval has proven very reliable for sterilizing carrier cattle in Australia.

Reduction of transmission

In some areas stringent control or elimination of the vectors may be a viable if expensive strategy particularly in Africa were a number of tick-borne diseases can be controlled by this strategy.

Attention should also be given to preventing iatrogenic transmission by disinfecting instruments after use on each animal.

References

Abdala AA; Mangold AJ; Torioni S, 1998. Control and eradication of anaplasmosis in a dairy herd. Veterinaria Argentina, 15(145):341-346; 10 ref.

African Union-Interafrican Bureau for Animal Resources, 2011. Panafrican Animal Health Yearbook 2011. Pan African Animal Health Yearbook, 2011:xiii + 90 pp. http://www.au-ibar.org/index.php?option=com_flexicontent&view=items&cid=71&id=109&Itemid=56&lang=en

Aguirre AA; McLean RG; Cook RS; Quan TJ, 1992. Serologic survey for selected arboviruses and other potential pathogens in wildlife from Mexico. Journal of Wildlife Diseases, 28(3):435-442; 27 ref.

Ahmadu B; Zulu LNK; Tuchili LM; Samui KL, 1997. The possible causes of calf mortality in Namwala district of Zambia. International Journal of Animal Sciences, 12(1):49-52; 9 ref.

Ajayi SA; Dipeolu OO, 1986. Prevalence of Anaplasma marginale, Babesia bigemina and B. bovis in Nigerian cattle using serological methods. Veterinary Parasitology, 22(1/2):147-149; 10 ref.

Akinboade OA; Dipeolu OO, 1984. Comparison of blood smear and indirect fluorescent antibody techniques in detection of haemoparasite infections in trade cattle in Nigeria. Veterinary Parasitology, 14(2):95-104; 25 ref.

Akinboade OA; Sadiq NA; Akinrinmade JF; Dipeolu OO; Nwufor KJ, 1986. Anaplasmosis of small ruminants in Nigeria: incidence and parasite identification through blood smear and latex agglutination test (LAT). International Journal of Zoonoses, 13(3):210-214; 15 ref.

Alfaro C; Toro Benitez M; García F; Valle A, 1998. Epidemiology of bovine anaplasmosis in the state of Monagas, Venezuela. Relationship with extrinsic and intrinsic characteristics of the host. Veterinaria Tropical, 23(1):65-79; 24 ref.

Al-Khafaji NJ; Rhaymah MS, 1993. Prevalence of clinical diseases in sheep in Ninevah province, Iraq. Iraqi Journal of Veterinary Sciences, 6(2):114-117; 9 ref.

Al-Khafaji NJ; Rhaymah MS; Al-Farwaji MI, 1995. Prevalence of clinical diseases in cattle in Mosul, Ninevah province, Iraq. Iraqi Journal of Veterinary Sciences, 8(1):145-150; 8 ref.

Alonso M; Camus E; Rodriguez Diego J; Bertaudière L; Tatareau JC; Liabeuf JM, 1992. Current position of bovine haemoparasitoses in Martinique (French West Indies). Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 45(1):9-14; 14 ref.

Alvarez V; Herrero MV, 1996. A bibliographic review of Boophilus microplus (Acari: Ixodidae) and the diseases it transmits in Costa Rica. Ciencias Veterinarias (Heredia), 19(1/2):1-9; 37 ref.

Amaral LBS; Valente FAT, 1971. Ocorrência de moléstias nos rebanhos bovinos do Estado de São Paulo, no triênio 1965/1967. V. Piroplasmose e anaplasmose nas regiões de Campinas e Vale do Paraíba, São Paulo. O Biológico, 37:56-61.

Andel JMvan; Dwinger RH; Alvarez JA, 1997. Study of Anaplasma and Babesia infection rates of cattle and associated ticks in the south coast of Guatemala. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 50(4):285-292; 20 ref.

Anziani OS; Tarabla HD; Ford CA; Galleto C, 1987. Vaccination with Anaplasma centrale: response after an experimental challenge with Anaplasma marginale. Tropical Animal Health and Production, 19(2):83-87; 19 ref.

Araújo FR; Madruga CR; Leal CRB; Bastos PAS; Marques APC, 1998. Prevalence of antibodies to Anaplasma marginale in dairy herds in Bahia State, Brazil. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 50(3):243-246; 14 ref.

Arslan SH; Shukur AA, 1994. Clinical and haematological studies on theileriosis and anaplasmosis in local breed cattle in Mosul region. Iraqi Journal of Veterinary Sciences, 7(2):93-100; 23 ref.

Artemenko LP, 1973. A study of the epizootiology and prevention of anaplasmosis in cattle in the forested regions of the Ukraine. Veterinariya, 34:91-94.

Artemenko LP, 1977. Economic losses on farms with endemic bovine anaplasmosis. Byulleten Vsesoyuznogo Instituta Eksperimental noi Veterinarii, 31:42-43.

Artiles J, Alves-Branco FPJ et al. , 1995. Prevalência de Babesia bovis, Babesia bigemina e Anaplasma marginale no municípo de Bagé. Revista Brasileira de Parasitologia Veterinaria, 4(2):79.

Athayde CR; Silva WW; Cavalcanti FRT, 1994. Surto epizoótico de babesiose e anaplasmose em bovinos na região de Patos. Anais: XXIII Congresso Brasileiro de Medicina Veterinaria, Olinda, Brazil.

Azuara LVM; Olguin YBA; Guerrero MC, 1993. Frecuencia de anaplasmosis clínica en bovinos de dos edades diferentes en tres ranchos del municipio de Tanima en Veracruz. Res. 3er Congreso Parasitología Veterinaria, Mérida, Mexico.

Badalov ET, 1989. Preventing piroplasmosis in cattle [in Tadzhikistan]. Veterinariya (Moskva), No. 6:37-40.

Baek BK; Chin CM; Kim BS; Kim JH; Cho CH; Rhee JM; Jung BT, 1989. Study on the antigenicity of Anaplasma marginale parasite in Korean native cattle. Korean Journal of Veterinary Public Health, 13(3):233-240; 26 ref.

Baek BK; Jin CM; Seo SY; Seo YW; Kim DS; Kakoma I, 1994. A study on the epidemiology of caprine anaplasmosis in Korea, I. Electron microscopic characterization of the etiologic agent. Korean Journal of Veterinary Research, 34(2):381-386; 24 ref.

Baek BK; Kim JH; Chin CM; Kim BS; Choi IH; Rhee JK; Rim BM, 1989. Ultrastructure of Anaplasma marginale in Korean native cattle. Korean Journal of Veterinary Public Health, 13(3):241-246; 14 ref.

Baek BK; Son KR, 1995. Study on the epidemiology of caprine anaplasmosis in Korea. III. Seasonal variation in haematological profiles. Korean Journal of Veterinary Research, 35(1):137-142; 35 ref.

Barré N, 1997. The ticks of ruminants of the Lesser Antilles: their biology, their economic importance and defensive strategies. Productions Animales, 10(1):111-119; 27 ref.

Barry DM; Niekerk CHvan, 1990. Anaplasmosis in improved Boer goats in South Africa artificially infected with Anaplasma ovis.. Small Ruminant Research, 3(2):191-197; 6 ref.

Behymer DE; Reimann HP; Utterback W; Elmi CD; Franti CE, 1991. Mass screening of cattle sera against 14 infectious disease agents, using an ELISA system for monitoring health in livestock. American Journal of Veterinary Research, 52(10):1699-1705; 5 ref.

Belem AMG; Mattioli RC; Jean O, 1994. Note on the prevalence of blood parasites (Babesia, Theileria, Anaplasma, and microfilariae) in wild animals from the Nazinga Game Ranch in Burkina Faso. Bulletin of Animal Health and Production in Africa, 42(3):183-186; 12 ref.

Benesi FJ, Howard DL et al. , 1999. A case of transplacental transmission of bovine anaplasmosis. Clinical and laboratory observations. Revista Brasileira de Ciencia Veterinaria, 6(3):175-176.

Berdie J; Cardozo H; Nari A; Solari M; Meeusen E, 1979. Prevalencia de Anaplasma marginale en un área del departamento Rivera, mediante la prueba de aglutinación en placa. Veterinaria (Montevideo), 15:55-59.

Berry S; Ibata G; Edwards S, 1981. Antibody formation to Babesia bovis and Anaplasma marginale in calves in Bolivia. Tropical Animal Health and Production, 13(4):240-241.

Bock R; Jackson L; Vos Ade; Jorgensen W, 2004. Babesiosis of cattle. Parasitology, 129(Supplement):S247-S269.

Bock RE; Kingston TG; Vos AJde, 1999. Effect of breed of cattle on innate resistance to infection with Anaplasma marginale transmitted by Boophilus microplus. Australian Veterinary Journal, 77(11):748-751; 27 ref.

Bock RE; Vos AJde; Kingston TG; McLellan DJ, 1997. Effect of breed of cattle on innate resistance to infection with Babesia bovis, B. bigemina and Anaplasma marginale. Australian Veterinary Journal, 75(5):337-340; 23 ref.

Borko C, 1997. Pathogenic bacteria and their tick vectors: a perfect parasitic balance?. Veterinarske Novice, 23(9):305-309; 31 ref.

Braccini GL; Chaplin EL; Stobbe NS; Araújo FAP; Santos NR, 1992. Protozoology and rickettsial findings of the laboratory of the Veterinary Faculty of the Federal University of Rio Grande Do Sul, Brazil, 1986-1990. Arquivos da Faculdade de Veterinária, UFRGS, 20:134-149; 11 ref.

Brizuela CM; Ortellado CA; Sanabria E; Torres O; Ortigosa D, 1998. The safety and efficacy of Australian tick-borne disease vaccine strains in cattle in Paraguay. Veterinary Parasitology, 76(1/2):27-41; 12 ref.

Bundy DA; Hylton GA; Wagner GG, 1983. Bovine haemoparasitic diseases in Jamaica. Tropical Animal Health and Production, 15(1):47-48.

Buriro SN; Phulan MS; Arijo AH; Memon AB, 1994. Incidence of some haemo-protozoans in Bos indicus and Bubalis bubalis in Hyderabad. Pakistan Veterinary Journal, 14(1):28-29; 17 ref.

Bäumgartner W; Schlerka G; Fumicz M; Stöger J; Awad-Masalmeh M; Schuller W; Weber P, 1992. Seroprevalence survey for Anaplasma marginale-infection of Austrian cattle. Journal of Veterinary Medicine. Series B, 39(2):97-104; 33 ref.

Callow LL, 1984. Arthropod-borne rickettsias of the blood. In: Anon, ed. Animal Health in Australia, Protozoal and rickettsial diseases. Canberra, Australian Bureau of Animal Health, AGPS, 177-202.

Camus E; Barré N, 1995. Vector situation of tick-borne diseases in the Caribbean islands. Veterinary Parasitology, 57(1/3):167-176; 35 ref.

Camus E; Montenegro-James S, 1994. Bovine anaplasmosis and babesiosis in the Lesser Antilles: risk assessment of an unstable epidemiologic situation. Veterinary Research, 25(2/3):313-317; 13 ref.

Cardozo H; Solari MA; Petraccia C; Nari A, 1981. Estudio epizootiologico de los hematozoarios transmitidos por Boophilus microplus en una area enzootica del Uruguay. IX Jornadas Uruguayas de Buiatria, Paysandu.

Carmichael IH; Hobday E, 1975. Blood parasites of some wild bovidae in Botswana. Onderstepoort Journal of Veterinary Research, 42(2):55-62.

Carrique Mas JJ; Widdowson MA; Cuellar AM; Ribera H; Walker AR, 2000. Risk of babesiosis and anaplasmosis in different ecological zones of Santa Cruz department, Bolivia. Veterinary Parasitology, 93(1):29-38.

Cavazzani AH, 1989. Epizootiological aspects of Anaplasma marginale in Mexico. FAO Animal Production and Health Paper, No. 75:310-314; 7 ref.

Ceci L; Brown D; Carelli G; Kirvar E; Sasanelli M; Sparagano O, 1997. Bovine theileriosis in Apulia caused by Theileria buffeli/orientalis. Atti della Società Italiana di Buiatria, 29:399-404; 10 ref.

Ceci L; Carelli G, 1999. Tick-borne diseases of livestock in Italy: general review and results of recent studies carried out in the Apulia region. Parassitologia, 41(Suppl. 1):25-29.

Ceci L; Kirvar E; Carelli G; Brown D; Sasanelli M; Sparagano O, 1997. Evidence of Theileria buffeli infection in cattle in southern Italy. Veterinary Record, 140(22):581-583; 12 ref.

cetindag M, 1996. The important ticks, tick-borne diseases and helminth infections of livestock in Turkey. Türkiye Parazitoloji Dergisi, 20(2):293-300; 54 ref.

Chansiri L, 1997. Tick-borne diseases in Thailand. Tropical Animal Health and Production, 29(4 (supplement)):52S.

Charyev OCh, 1992. Morphology and biology of piroplasms in sheep and in ticks. Izvestiya Akademii Nauk Turkmenistana. Seriya Biologicheskikh Nauk, No. 4:78-80; 3 ref.

Chitravel V; Lourdsamy M; Ravindranath TK; Prabhakaran V; Kokilaprabhakaran S, 1998. A report on the incidence of anaplasmosis in Jersey bulls. Indian Veterinary Journal, 75(3):256-257; 6 ref.

Chollet JY, 1995. High serological prevalence rates of bovine anaplasmosis in Northern Cameroon. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 48(1):17-18; 1 ref.

Chomel BB; Carniciu ML; Kasten RW; Castelli PM; Work TM; Jessup DA, 1994. Antibody prevalence of eight ruminant infectious diseases in California mule and black-tailed deer (Odocoileus hemionus). Journal of Wildlife Diseases, 30(1):51-59; 40 ref.

Clark RK; Boyce WM; Jessup DA; Elliott LF, 1993. Survey of pathogen exposure among population clusters of bighorn sheep (Ovis canadensis) in California. Journal of Zoo and Wildlife Medicine, 24(1):48-53; 19 ref.

Connell M; Hall WT, 1972. Transmission of Anaplasma marginale by the cattle tick Boophilus microplus. Australian Veterinary Journal, 48(8):477.

Connell ML, 1974. Transmission of Anaplasma marginale by the cattle tick Boophilus microplus. Queensland Journal of Agricultural and Animal Sciences, 31:185-193.

Cordoves CO; Arrieta M; Serrano E; Mesejo J; Fregel N; Fadraga M, 1989. Prognosis, surveillance and control of bovine anaplasmosis in Cuba. Revista Cubana de Ciencias Veterinarias, 20(1):17-36; 5 ref.

Cordovés CO; Fregel N; Camacho A; Leyva A, 1991. System for monitoring and control of haemoparasites in Cuba. Revista Cubana de Ciencias Veterinarias, 22(3):197-232; 3 ref.

Corrier DE, Vizcaino O et al. , 1980. Comparison of three methods of immunization against bovine anaplasmosis: an examination of postvaccinal effects. American Journal of Veterinary Research, 41(7):1062-1065.

Corrier DE; Guzman S, 1977. The effect of natural exposure to Anaplasma and Babesia infections on native calves in an endemic area of Colombia. Tropical Animal Health and Production, 9(1):47-51.

Corrier DE; Kuttler KL; Terry MK, 1983. Observations on anaplasmosis following field exposure to heavy and light infestations with Boophilus microplus.. Veterinary Parasitology, 13(2):187-190; 13 ref.

Cossío-Bayúgar R; Rodríguez SD; García-Ortiz MA; García-Tapia D; Aboytes-Torres R, 1997. Bovine anaplasmosis prevalence in northern Veracruz state, Mexico. Preventive Veterinary Medicine, 32(3/4):165-170; 22 ref.

Cuéllar AM, Carrique JJ et al. , 1998. Serological evaluation of babesiosis and anaplasmosis in the department of Santa Cruz. Summary 16th Panam. Congr. Vet. Sci, Santa Cruz de la Sierra, Spain.

Dalagnol CA; Martins E; Madruga CR, 1995. Prevalência de anticorpos contra Babesia bovis, Babesia bigemina, Anaplasma marginale em bovinos de corte na região de clima Cfb. Revista Brasileira de Parasitologia Veterinaria, 4(2):220.

Dantas MDO, Nascimento GAJD et al. , 1999. Estudo do complexo tristeza parasitaria bovina e seu quadro eritrocitário. An. 16 Congr. Est. Med. Vet., Gramado.

Davis HE; Dimopoullos GT; Roby TO, 1970. Anaplasmosis transmission: Inoculation by the ocular route. Research in Veterinary Science, 11:594-595.

Deem SL; Perry BD; Katende JM; McDermott JJ; Mahan SM; Maloo SH; Morzaria SP; Musoke AJ; Rowlands GJ, 1993. Variations in prevalence rates of tick-borne diseases in Zebu cattle by agroecological zone: implications for East Coast fever immunization. Preventive Veterinary Medicine, 16(3):171-187; 33 ref.

Delgado A; Fernadez A; Fregel N, 1976. Anaplasmose et piroplasmose bovines. Considérations épizootiologiques et mesures de lutte dans la République de Cuba. Bulletin de L'Office International des Epizootics, 86:117-121.

Descazeaux MJ, 1924. L´anaplasmose au Chili. Bulletin de la Société de Pathologie exotique, 17:639-642.

Dissamarn R; Aranyakananda P; Thirapat K, 1968. Anaplasmosis and the prophylactic measures in Thailand. Bulletin of Epizootic Diseases of Africa, 16(1):65-70.

Dreyer K; Fourie LJ; Kok DJ, 1998. Epidemiology of tick-borne diseases of cattle in Botshabelo and Thaba Nchu in the Free State Province. Onderstepoort Journal of Veterinary Research, 65(4):285-289; 24 ref.

Egbe-Nwiyi TN; Salako MA; Otukonyong EE, 1997. Observations on naturally occurring bovine anaplasmosis in arid zone of North-Eastern Nigeria: prevalence, haematological and pathological changes. Studies and Researches in Veterinary Medicine, 5:95-99; 30 ref.

Elliott LF; Boyce WM; Clark RK; Jessup DA, 1994. Geographic analysis of pathogen exposure in bighorn sheep (Ovis canadensis). Journal of Wildlife Diseases, 30(3):315-318; 10 ref.

El-Metenawy TM, 2000. Prevalence of blood parasites among cattle at the central area of Saudi Arabia. Veterinary Parasitology, 87(2/3):231-236; 6 ref.

El-Seify MA; Eissa NA, 1990. Some clinico-pathological studies on cattle naturally infected with blood parasites in Beni-Suef Governorate. Egyptian Journal of Comparative Pathology and Clinical Pathology, 3(1):37-43; 22 ref.

Ewing SA; Panciera RJ; Kocan KM; Ge NL; Welsh RD; Olson RW; Barker RW; Rice LE, 1997. A winter outbreak of anaplasmosis in a nonendemic area of Oklahoma: a possible role for Dermacentor albipictus. Journal of Veterinary Diagnostic Investigation, 9(2):206-208; 18 ref.

Fadraga M; Cordovés CO; Puentes T, 1991. Circulation of antibodies to haemoparasites in cattle (Bos taurus) of high genetic value in Cuba. Revista Cubana de Ciencias Veterinarias, 22(3):249-255; 7 ref.

Fanikiso M; Ndzinge IT, 1992. Situation report on tick infestation of livestock, tick-borne disease and tick control methods in Botswana. Insect Science and its Application, 13(4):645-648; 2 ref.

FAO, 1975. Sanidad animal. Bolivia. Enfermedades transmitidas por la garrapata.: FAO, Inf. Técn, AG:DP/BOL/73/012.

Figueroa Millán JV; Cantó Alarcón GJ; Ramos Aragón JA; Rojas Ramírez EE; Santiago Valencia C; Granjeno Colín G; García Ortiz MA; Parrodi F, 1999. Evaluation of an inactivated Anaplasma marginale vaccine (Plazvax) under field conditions. Veterinaria México, 30(3):221-225; 8 ref.

Foil LD, 1989. Tabanids as vectors of disease agents. Parasitology Today, 5(3):88-96; 63 ref.

Fragoso Sánchez H, 1991. La anaplasmosis bovina en México. 2do Sem. Int. Parasitol, Oaxtepec, 153-160.

Franzolin Neto R; Dell´Porto A; Lacaz Ruiz R, 1989. Anaplasmosis and babesiosis: a clinical case in buffalo (Bubalus bubalis) calf in Brazil. Buffalo Bulletin, 8(3).

Fumicz M, 1991. Serological survey for Anaplasma marginale infection among cattle in Austria. Wiener Tierärztliche Monatsschrift, 78(4):136; [Abstract of Dissertation, University of Veterinary Medicine, Vienna, Austria.].

Gale KR; Dimmock CM; Gartside M; Leatch G, 1996. Anaplasma marginale: detection of carrier cattle by PCR-ELISA. International Journal for Parasitology, 26(10):1103-1109; 25 ref.

Gale KR; Leatch G; DeVos AJ; Jorgensen WK, 1996. Anaplasma marginale: effect of challenge of cattle with varying doses of infected erythrocytes. International Journal for Parasitology, 26(12):1417-1420; 18 ref.

Ge NieLin; Kocan KM; Ewing SA; Blouin EF; Edwards WL; Murphy GL; Dawson LJ, 1997. Use of a non-radioactive DNA probe for detection of Anaplasma marginale infection in field cattle: comparisons with complement fixation serology and microscopic examination. Journal of Veterinary Diagnostic Investigation, 9(1):39-43; 25 ref.

Gitau GK; Perry BD; Katende JM; McDermott JJ; Morzaria SP; Young AS, 1997. The prevalence of serum antibodies to tick-borne infections in cattle in smallholder dairy farms in Murang'a District, Kenya; a cross-sectional study. Preventive Veterinary Medicine, 30(2):95-107; 24 ref.

Gloss RM, 1964. Experiências com o Anaplasma centrale com finalidade de facilitar o serviço de premunição. Anais: III Conferência da SOVERGS, Porto Alegre, 65-71.

Goff WL; Winward LD, 1985. Detection of geographic isolates of Anaplasma marginale, using polyclonal bovine antisera and microfluorometry. American Journal of Veterinary Research, 46(11):2399-2400; 9 ref.

Gonçalves PM, 2000. Epidemiology and control of bovine babesiosis and anaplasmosis in southeast Brazil. Ciência Rural, 30(1):187-194; 44 ref.

Gonzalez EF; Long RF; Todorovic RA, 1978. Comparisons of the complement-fixation, indirect fluorescent antibody, and card agglutination tests for the diagnosis of bovine anaplasmosis. American Journal of Veterinary Research, 39(9):1538-1541.

Gueye A; Mbengue M; Diouf A, 1989. Ticks and haemoparasitoses of livestock in Senegal. III. The North Sudanian zone. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 42(3):411-420; 8 ref.

Gueye A; Mbengue M; Diouf A, 1989. Ticks and haemoparasitoses of livestock in Senegal. IV. The south-Sudanian zone. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 42(4):517-528; 14 ref.

Gueye A; Mbengue M; Diouf A, 1994. Ticks and haemoparasitoses among livestock in Senegal. VI. The Sudano-Sahelian zone. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 47(1):39-46; 13 ref.

Gueye A; Mbengue M; Diouf A; Sonko ML, 1993. Ticks and haemoparasitoses of livestock in Senegal. V. The North-Guinean zone. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 46(4):551-561; 14 ref.

Guglielmone AA, 1994. Epidemiología y control de los hemoparásitos (Babesia y Anaplasma) de los vacunos en la Argentina. In: Fiel C, Nari A, eds. Enfermedades parasitarias de importancia económica en la Argentina y el Uruguay. Montevideo, Editorial Hemisferio Sur, 461-479.

Guglielmone AA, 1995. Epidemiology of babesiosis and anaplasmosis in South and Central America. Veterinary Parasitology, 57(1/3):109-119; 4 pp. of ref.

Guglielmone AA; Abdala AA; Anziani O; Mangold AJ; Volpogni MM; Vanzini VR, 1997. Different seasonal occurrence of anaplasmosis outbreaks in beef and dairy cattle in an area of Argentina free of Boophilus microplus ticks. Veterinary Quarterly, 19(1):32-33; 12 ref.

Guido MC; Dell'Porto A; Fujii TU; Artes R, 1994. Prevalence of hemoparasites in buffaloes from Ribeira Valley, south coast of Sao Paulo state - Brazil. Proceedings 4th World Buffalo Congress, Sao Paulo, Brazil, 27-30 June, 1994: Volume 2., 325-327; 7 ref.

Ha Thuy Hanh; Nguyen Dang Khai; Pham Sy Lang; Phan Dich Lan; Nguyen Duc Tan; Hoang Manh Lam, 1997. Blood parasites of cattle in Daklak province, Vietnam. Khoa Hoc Ky Thuat Thu Y, 4(4):50-53.

Ha^dot under~ Thúy Ha^dot under~nh; Nguyên Dang Kha^dot over~i; Phan Di^dot under~ch Lân; Pha^dot under~m Sy Lang, 1996. Observations on hemosporidian infections in dairy cattle in the Hanoi area. Khoa Hoc Ky Thuat Thu Y, 3(2):61-64; 7 ref.

Hart LT; Todd WJ; Luther DG; Hoyt PG; Morris NG; McDonough KC; Hoyt MJ, 1987. Progress toward an improved vaccine for anaplasmosis. Louisiana Agriculture, 31(1):3, 6.

Hashemi-Fesharki R, 1997. Tick-borne diseases of sheep and goats and their related vectors in Iran. Parassitologia (Roma), 39(2):115-117; 6 ref.

Henry ET; Norman BB; Fly DE; Wichmann RW; York SM, 1983. Effects and use of a modified live Anaplasma marginale vaccine in beef heifers in California. Journal of the American Veterinary Medical Association, 183(1):66-69.

Hermans P; Dwinger RH; Buening GM; Herrero MV, 1994. Seasonal incidence and hemoparasite infection rates of ixodid ticks (Acari: Ixodidae) detached from cattle in Costa Rica. Revista de Biología Tropical, 42(3):623-632; 19 ref.

Herrero MV; Perez E; Goff WL; Torioni de Echaide S; Knowles DP; McElwain TF; Alvarez V; Alvarez A; Buening GM, 1998. Prospective study for the detection of Anaplasma marginale Theiler, 1911 (Rickettsiales: Anaplasmataceae) in Costa Rica. Annals of the New York Academy of Sciences, 849:226-233; 22 ref.

Hidalgo RJ; Palmer GH; Jones EW; Brown JE; Ainsworth AJ, 1989. Infectivity and antigenicity of Anaplasma marginale from tick cell culture. American Journal of Veterinary Research, 50(12):2033-2036; 9 ref.

Hoffmann G; Horchner F; Schein E; Gerber HC, 1971. Seasonal appearance of ticks and piroplasms in domestic animals in the Asiatic provinces of Turkey. Berl Munch Tierarztl Wochenschr, 84(8):152-156.

Horn S, 1983. Prováveis prejuízos causados pelos carrapatos. Brasília: Bol. Defesa Sanitária Animal, No. Especial.

Hugh-Jones ME; Hubbert W, 1988. Seroconversion rates to bovine leukosis virus, bluetongue virus, Leptospira hardjo and Anaplasma marginale infections in a random series of Louisiana beef cattle. Acta Veterinaria Scandinavica, Suppl. 84:107-109; [5th International Symposium on Veterinary Epidemiology and Economics, Copenhagen, Denmark, 25-29 July, 1988.]; 5 ref.

Hugh-Jones ME; Scotland K; Applewhaite LM; Alexander FM, 1988. Seroprevalence of anaplasmosis and babesiosis in livestock on St. Lucia, 1983. Tropical Animal Health and Production, 20(3):137-139; 4 ref.

Hungerford LL; Smith RD, 1996. Spatial and temporal patterns of bovine anaplasmosis as reported by Illinois veterinarians. Preventive Veterinary Medicine, 25(3/4):301-313; 21 ref.

Hungerford LL; Smith RD, 1997. Variations in seroprevalence and host factors for bovine anaplasmosis in Illinois. Veterinary Research Communications, 21(1):9-18; 24 ref.

Ilemobade AA, 1992. Anaplasmosis, babesiosis and cowdriosis in the West African sub-region: distribution, economic importance and control measures. Recent developments in the control of anaplasmosis, babesiosis and cowdriosis, 43-47; 3 ref.

James MA; Coronado A; Lopez W; Melendez R; Ristic M, 1985. Seroepidemiology of bovine anaplasmosis and babesiosis in Venezuela. Tropical Animal Health and Production, 17(1):9-18; 15 ref.

Jessup DA; Goff WL; Stiller D; Oliver MN; Bleich VC; Boyce WM, 1993. A retrospective serologic survey for Anaplasma spp. infection in three bighorn sheep (Ovis canadensis) populations in California. Journal of Wildlife Diseases, 29(4):547-554; 35 ref.

Jithendran KP, 1997. Blood protista of cattle and buffaloes in Kangra Valley, Himachal Pradesh. Indian Journal of Animal Sciences, 67(3):207-208; 3 ref.

Jones WE; Kliewer IO; Norman BB; Brock WE, 1968. Anaplasma marginale infection in young and aged cattle. American Journal of Veterinary Research, 29(3):535-544.

Jongejan F; Perry BD; Moorhouse PDS; Musisi FL; Pegram RG; Snacken M, 1988. Epidemiology of bovine babesiosis and anaplasmosis in Zambia. Tropical Animal Health and Production, 20(4):234-242; 18 ref.

Jorgensen W; Weilgama DJ; Navaratne M; Weerasinghe C; Perera PSG, 1988. Observations on the prevalence of Babesia and Anaplasma infections in some Government livestock farms in Sri Lanka. Sri Lanka Veterinary Journal, 36:56-57.

Jorgensen WK; Weilgama DJ; Navaratne M; Dalgliesh RJ, 1992. Prevalence of Babesia bovis and Anaplasma marginale at selected localities in Sri Lanka. Tropical Animal Health and Production, 24(1):9-14; 7 ref.

Kabagambe J; Nshimiyimana A; Muberuka J; Nyiligira JB, 1988. The enzootic diseases of cattle at Bugesera. Bulletin Agricole du Rwanda, 21(3):159-168; 3 ref.

Kano ES, Vidotto O et al. , 1999. Análise antigênica de isolados de Anaplasma marginale de diferentes regiões geográficas por western blotting. Anais do XI Seminário Brasileiro de Parasitologia Veterinária, Salvador, Brazil.

Keirans JE; Hutcheson HJ; Durden LA; Klompen JSH, 1996. Ixodes (Ixodes) scapularis (Acari: Ixodidae): redescription of all active stages, distribution, hosts, geographical variation, and medical and veterinary importance. Journal of Medical Entomology, 33(3):297-318; many ref.

Kessler RE; Sastre AM; Moreira MA; Madruga CR; Honer MR, 1991. Experiments in Brazil with live attenuated vaccines for Babesia bovis, B. bigemina, Anaplasma marginale and A. centrale preserved by freezing. Revista Cubana de Ciencias Veterinarias, 22(3):189-196; 5 ref.

Kessler RH; Madruga CR; Fabrício de Jesus E; Semprebom DV, 1987. Isolation of pure strains of Babesia bovis, Babesia bigemina and Anaplasma marginale from cattle in an enzootic area. Pesquisa Agropecuária Brasileira, 22(6):747-752; 19 ref.

Knowles D; Echaide STde; Palmer G; McGuire T; Stiller D; McElwain T, 1996. Antibody against an Anaplasma marginale MSP5 epitope common to tick and erythrocyte stages identifies persistently infected cattle. Journal of Clinical Microbiology, 34(9):2225-2230; 24 ref.

Knowles RT, Montrose M et al. , 1982. Clinical and serological evidence of bovine babesiosis and anaplasmosis in St. Lucia. Veterinary Parasitology, 10(4):307-311.

Kocan KM, 1994. Anaplasmosis in Oklahoma and the South Central United States. Proceedings of the United States Animal Health Association, 98:216-222; 28 ref.

Kocan KM, 1995. Targeting ticks for control of selected hemoparasitic diseases of cattle. Veterinary Parasitology, 57(1/3):121-151; 12 pp. of ref.

Kocan KM; Fuente Jde la; Blouin EF; Garcia-Garcia JC, 2004. Anaplasma marginale (Rickettsiales: Anaplasmataceae): recent advances in defining host-pathogen adaptations of a tick-borne rickettsia. Parasitology, 129(Supplement):S285-S300.

Kocan KM; Fuente Jde la; Guglielmone AA; Meléndez RD, 2003. Antigens and alternatives for control of Anaplasma marginale infection in cattle. Clinical Microbiology Reviews, 16(4):698-712.

Kocan KM; Goff WL; Stiller D; Edwards W; Ewing SA; Claypool PL; McGuire TC; Hair JA; Barron SJ, 1993. Development of Anaplasma marginale in salivary glands of male Dermacentor andersoni.. American Journal of Veterinary Research, 54(1):107-112; 28 ref.

Kocan KM; Stiller D; Goff WL; Claypool PL; Edwards W; Ewing SA; McGuire TC; Hair JA; Barron SJ, 1992. Development of Anaplasma marginale in male Dermacentor andersoni transferred from parasitemic to susceptible cattle. American Journal of Veterinary Research, 53(4):499-507; 28 ref.

Kreier JP; Ristic M, 1963. Anaplasmosis. Morphological characteristics of the parasites present in the blood of calves infected with the Oregon strain of Anaplasma marginale. American Journal of Veterinary Research, 24:676-687.

Kreier JP; Ristic M, 1972. Definition and taxonomy of Anaplasma species with emphasis on morphologic and immunologic features. Zeitschrift Fur Tropenmedizin Und Parasitologie, 23:88-98.

Kutschera G, 1995. Epidemiological study of anaplasmosis in cattle herds in Steiermark, Austria. Wiener Tierärztliche Monatsschrift, 82(6):197; [Abstract of Dissertation, Veterinary Medical University, Vienna, Austria.].

Kuttler KL, 1967. A study of the immunological relationship of Anaplasma marginale and Anaplasma centrale. Research in Veterinary Science, 8(4):467-471.

Kuttler KL, 1979. Current anaplasmosis control techniques in the United States. Journal of the South African Veterinary Association, 50(4):314-320.

Kuttler KL; Adams LG; Zaraza H, 1970. Estudio epizotiológico del Anaplasma marginale y del Trypanosoma theileri en Colombia. Revista Institituto Colombiano Agropecuario, 5:127-148.

Kuttler KL; Zaugg JL; Johnson LW, 1984. Serologic and clinical responses of premunized, vaccinated, and previously infected cattle to challenge exposure by two different Anaplasma marginale isolates. American Journal of Veterinary Research, 45(11):2223-2226; 13 ref.

Lagaggio VRA, Correa GLB et al. , 1997. Confrimacao de diagnóstico de tristeza parasitária bovina entre 1987 e 1996. Revista Brasileira de Parasitologia Veterinaria, 6(Suppl. 1):312.

Latif AA; Rowlands GJ; Punyua DK; Hassan SM; Capstick PB, 1995. An epidemiological study of tick-borne diseases and their effects on productivity of zebu cattle under traditional management on Rusinga Island, western Kenya. Preventive Veterinary Medicine, 22(3):169-181; 22 ref.

Lawrence JA; Musisi FL; Mfitilodze MW; Tjornehoj K; Whiteland AP; Kafuwa PT; Chamambala KE, 1996. Integrated tick and tick-borne disease control trials in crossbred dairy cattle in Malawi. Tropical Animal Health and Production, 28(4):280-288; 10 ref.

Lawrence JA; Norval RAI, 1987. A history of ticks and tick-borne diseases of cattle in Rhodesia. Historia Medicinae Veterinariae, 12(4):89-101; 16 ref.

Lee JooMook; Kwon OhDeog; Song HeeJong; Park JinHo; Choi KyoungSeong, 1997. Anaplasma marginale infection in Holstein calves during winter. Korean Journal of Veterinary Research, 37(4):911-916; 38 ref.

Levasseur G, 1991. Bovine babesiosis in France. Bovine anaplasmosis. Bulletin des G.T.V., No. 6:163-169; 11 ref.

Lora CA; Koechlin A, 1969. An attenuated Anaplasma marginale vaccine in Peru. American Journal of Veterinary Research, 30(11):1993-1998.

Lu WenShun; Lu WenXiang; Zhang QiCai; Yu Feng; Dou HuiFang; Yin Hong, 1997. Ovine anaplasmosis in northwest China. Tropical Animal Health and Production, 29(4 (supplement)):16S-18S.

Lu WenXiang; Lu WanShun; Zhang QiCai; Luo JianXun; Yin Hong; Dou HuiFang, 1995. Survey of the species of tick-transmitted haemocytozoa of cattle and the distribution features in China. Chinese Journal of Veterinary Science and Technology, 25(8):13-16; 6 ref.

Lu WS; Zhang QC; Lu WX; Dou HF; Yu F; Ji ZD; Hu TY; Song BG; Hang JY; Gao DF; Bao YT, 1989. Studies on anaplasmosis in goat: distrubtion of Anaplasma ovis in northwest China. Chinese Journal of Veterinary Science and Technology, 21(3):3-5; [1 tab.]; 4 ref.

Luther DG; Hart LT; Morris NG; McRae B; Todd WJ, 1990. Field trial of an experimental anaplasmosis vaccine in Louisiana. Proceedings - Annual Meeting of the United States Animal Health Association, 94:35-38.

Luther DG; Hart LT; Morris NG; Todd WJ, 1990. An experimental anaplasmosis vaccine for cattle. Louisiana Agriculture, 33(3):16-17.

Maas J; Buening GM; Porath W, 1981. Serologic evidence of Anaplasma marginale infection in white-tailed deer (Odocoileus virginianus) in Missouri. Journal of Wildlife Diseases, 17(1):45-47.

Maas J; Lincoln SD; Coan ME; Kuttler KL; Zaugg JL; Stiller D, 1986. Epidemiologic aspects of bovine anaplasmosis in semiarid range conditions of south central Idaho. American Journal of Veterinary Research, 47(3):528-533; 26 ref.

Madruga CR; Aycardi E; Putt N, 1983. Epidemiology of bovino anaplasmosis and babesiosis in the Savannah region of the Mato Grosso do Sul State (Brazil). I. Prevalence. Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, 35(5):631-640; 24 ref.

Madruga CR; Gomes RF; Shenk MAM, 1984. Etiologia de algumas doenças de bezerros de corte no estado de Mato Grosso do Sul. Campo Grande, Brazil: EMBRAPA-CNPGC.

Madruga CR; Honer MR; Schenk MAM; Curvo JBE, 1987. Preliminary analysis of epidemiological parameters of tickborne diseases of cattle in Mato Grosso do Sul. Pesquisa em Andamento, Centro Nacional de Pesquisa de Gado de Corte, EMBRAPA, Brazil, No. 38:7 pp.

Madruga CR; Kessler RH; Gomes A; Schenk MAM; Andrade DFde, 1985. Levels of antibodies and Anaplasma marginale parasitaemia in Nelore, Ibage and Nelore crossbred calves in an endemic area. Pesquisa Agropecuária Brasileira, 20(1):135-142; 32 ref.

Magonigle RA; Eckblad WP; Lincoln SD; Frank FW, 1981. Anaplasma ovis in Idaho sheep. American Journal of Veterinary Research, 42(2):199-201.

Majaj-Büscher H, 1992. Ectoparasites and blood parasites of goats in Jordan. Untersuchungen zum Befall von Ziegen mit Ektoparasiten und Blutparasiten in Jordanien., 119 pp.; 15 pp. of ref.

Marutyan EM; Zaratsyan AA, 1986. Epizootic course of bovine anaplasmosis in Armenia. Veterinariya, Moscow, USSR, No.12:46-47.

Massard CL, 1986. Progresos en las investigaciones de hemoparásitos en la UFRJ, Rio de Janeiro. 2do Seminário Garrapatas, enfermedades transmitidas por e insectos nocivos para los bovinos en los países sudamericanos del cono sur, Porot Alegre, Brazil.

Mattioli RC; Bah M; Faye J; Kora S; Cassama M, 1993. A comparison of field tick infestation on N'Dama, zebu and N'Damazebu crossbred cattle. Veterinary Parasitology, 47(1-2):139-148; 31 ref.

Mattioli RC; Janneh L; Corr N; Faye JA; Pandey VS; Verhulst A, 1997. Seasonal prevalence of ticks and tick-transmitted haemoparasites in traditionally managed N'Dama cattle with reference to strategic tick control in the Gambia. Medical and Veterinary Entomology, 11(4):342-348; 38 ref.

McCauley EH; Pérez E, 1980. Investigaciones sobre el control de garrapatas y de las enfermedades por ellas transmitidas en Costa Rica: evaluación económica. Ciencias Veterinarias, 2:219-223.

McGinnis B; Zingeser J; Grant G; Hugh-Jones ME, 1988. Bovine anaplasmosis in Jamaica. Tropical Animal Health and Production, 20(1):42-44; 3 ref.

McGuire TC; Davis WC; Brassfield AL; McElwain TF; Palmer GH, 1991. Identification of Anaplasma marginale long-term carrier cattle by detection of serum antibody to isolated MSP-3. Journal of Clinical Microbiology, 29(4):788-793; 47 ref.

McHardy N, 1984. Immunization against anaplasmosis- a review. Preventive Veterinary Medicine, 2:135-146.

Mekonnen S; Castro J; Gebre S; Hussein I; Regassa A, 1992. Ticks, tick-borne diseases and their control in western Ethiopia. Insect Science and its Application, 13(4):661-664; 2 ref.

Meléndez RD; Forlano M, 1997. Seroprevalence and incidence of babesiosis and anaplasmosis in a Carora breed herd from Venezuela. Revista Brasileira de Parasitologia Veterinária, 6(2):105-109; 14 ref.

Melo MAD; Rocha JMD; Alves LC, 1993. Diagnóstico da situacao da anaplasmose bovina no município de Garanhuns/Pernambuco. Revista Brasileira de Parasitologia Veterinaria, 2(Suppl. 1):103.

Melo VSP; Passos LMF; Facury Filho EJ; Ribeiro MFB, 1999. Infecao natural por Anaplasma marginale em bezerras de fazendas leiteiras da regiao Metalúrgica de Minas Gerais. An. 11. Seminário Brasileiro de Parasitologia Veterinária, Salvador, Brazil, 243-244.

Miranpuri GS, 1988. Ticks parasitizing the Indian buffalo (Bubalus bubalis) and their possible role in disease transmission. Veterinary Parasitology, 27(3-4):357; 12 ref.

Mirón CA, 1978. Prevalencia de la anaplasmosis bovina en el departamento de San Miguel. Agric. El Salvador, 17:12-24.

Misraulia KS; Sisodia RS; Mehta HK, 1988. Incidence of anaplasmosis in exotic and crossbred cattle in and around Indore and Mhow, Madhya Pradesh. Indian Veterinary Journal, 65(7):574-576; 8 ref.

Mohan RN; Pathak RC, 1967. Prevalence of anaplasmosis in ruminants in Northern India. American Journal of Veterinary Research, 28(123):599-601.

Molina J; Montenegro M, 1997. Case report - Anaplasmosis in two Philippine cows. Philippine Journal of Veterinary Medicine, 26(1-2):181-187.

Molloy JB; Bowles PM; Knowles DP; McElwain TF; Bock RE; Kingston TG; Blight GW; Dalgliesh RJ, 1999. Comparison of a competitive inhibition ELISA and the card agglutination test for detection of antibodies to Anaplasma marginale and Anaplasma centrale in cattle. Australian Veterinary Journal, 77(4):245-249; 13 ref.

Montenegro-James S, 1992. Distribution, economic importance and control measures for anaplasmosis and babesiosis in South America. Recent developments in the control of anaplasmosis, babesiosis and cowdriosis: Proceedings of a Workshop held at ILRAD, Nairobi, Kenya 13-15 May 1991., 29-42; 47 ref.

Morel PC, 1967. Etude sur les tiques du bétail en Guadeloupe et Martinique. II. Agents pathogèns transmis par les tiques. Revue D Élevage et de Médecine Véterinaire des Pays Tropicaux, 20:291-299.

Morley RS; Hugh-Jones ME, 1989. Seroprevalence of anaplasmosis in the Red River Plains and South-east areas of Louisiana. Veterinary Research Communications, 13(4):287-296; 15 ref.

Morley RS; Hugh-Jones ME, 1989. The cost of anaplasmosis in the Red River plains and south-east areas of Louisiana. Veterinary Research Communications, 13(5):349-358; 17 ref.

Movsum-zade A; Agaev A, 1976. The control of parasitic diseases of cattle. Veterinariya, 4:66-67.

Nakamura Y; Kawazu S; Minami T, 1993. Antigen profiles of Anaplasma ovis and A. mesaeterum and cross infection trials with them and A. marginale. Veterinary Microbiology, 37(1/2):19-30; 19 ref.

Nari A; Solari M; Cardozo H, 1979. Hemovacuna para el control de Babesia spp. y Anaplasma marginale en el Uruguay. Veterinaria (Montevideo, Uruguay), 15:137-148.

Ndahiriwe M, 1999. Tick-borne diseases in eastern Zaire [Congo Democratic Republic]. Tick and tick-borne disease control in East, Central and Southern Africa, 1991-1994. Proceedings of a joint OAU, FAO and ILRAD workshop held in Lilongwe, Malawi, 25-28 April 1994., 48-49.

Ndarathi CM; Waghela S; Semenye PP, 1989. Prevalence of ticks on rangeland domestic ruminants in Kajiado district, Kenya. Bulletin of Animal Health and Production in Africa, 37(3):209-212; 10 ref.

Ndi C; Bayemi PH; Ekue FN; Tarounga B, 1991. Preliminary observations on ticks and tick-borne diseases in the North West Province of Cameroon. I. Babesiosis and anaplasmosis. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 44(3):263-265; 17 ref.

Ndung'u LW; Aguirre C; Rurangirwa FR; McElwain TF; McGuire TC; Knowles DP; Palmer GH, 1995. Detection of Anaplasma ovis infection in goats by major surface protein 5 competitive inhibition enzyme-linked immunosorbent assay. Journal of Clinical Microbiology, 33(3):675-679; 33 ref.

Nguyen Van Hau; Nhu Van Thu; Ha Thuy Hanh; Le Minh Sat, 1999. A preliminary study on application of polymerase chain reaction in diagnosis of haemosporidiosis in cattle. Khoa Hoc Ky Thuat Thu Y (Veterinary Sciences and Techniques), 6(1):48-52.

Nicholls MJ; Ibata G; Rodas FV, 1980. Prevalence of antibodies to Babesia bovis and Anaplasma marginale in dairy cattle in Bolivia. Tropical Animal Health and Production, 12(1):48-49.

Nogueira FRC; Massard CL; Barreira JD, 1991. Parasitic diseases of cattle. Epidemiology, clinical signs, diagnosis, control measures and prophylaxis. Circular Técnica - Empresa de Pesquisa Agropecuária do Estado do Rio de Janeiro, 12:5-14; 16 ref.

Norval RAI; Fivaz BH; Lawrence JA; Brown AF, 1984. Epidemiology of tick-borne diseases of cattle in Zimbabwe. II. Anaplasmosis. Tropical Animal Health and Production, 16(2):63-70; 29 ref.

Obaldía NIII, 1992. History of tickborne diseases of animals in Panama. Notas Veterinarias, 2(1):15-17; 17 ref.

Office International des Epizooties, 1999. World Animal Health in 1999. Paris, France: OIE.

OIE Handistatus, 2002. World Animal Health Publication and Handistatus II (dataset for 2001). Paris, France: Office International des Epizooties.

OIE Handistatus, 2003. World Animal Health Publication and Handistatus II (dataset for 2002). Paris, France: Office International des Epizooties.

OIE Handistatus, 2004. World Animal Health Publication and Handistatus II (data set for 2003). Paris, France: Office International des Epizooties.

OIE Handistatus, 2005. World Animal Health Publication and Handistatus II (data set for 2004). Paris, France: Office International des Epizooties.

OIE, 2012. World Animal Health Information Database. Version 2. World Animal Health Information Database. Paris, France: World Organisation for Animal Health. http://www.oie.int/wahis_2/public/wahid.php/Wahidhome/Home

Oliveira AAde; Padreira PAS; Almeida MFRSde, 1992. Calf diseases. II. Epidemiology of anaplasmosis in the state of Sergipe. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 44(5):377-386; 11 ref.

Oliveira JB; Madruga CR; Schenck MAM; Massard CL, 1999. Caracterização antigênica de isolados de Anaplasma marginale dos Estados de Pernambuco e Mato Grosso do Sul. Anais do XI Seminário Brasileiro de Parasitologia Veterinária, Salvador, 245-246.

Osman AM, 1997. Major tick-borne diseases of sheep and goats in the Sudan. Parassitologia (Roma), 39(2):143-144; 8 ref.

Osorno MB; Solana PM; Perez JM; Lopez TR, 1975. Study of an attenuated Anaplasma marginale vaccine in Mexico natural challenge of immunity in an enzootic area. American Journal of Veterinary Research, 36(5):631-6333.

Otim C; Wilson AJ; Campbell RS, 1980. A comparative study of experimental anaplasmosis in Bos indicus and Bos taurus cattle. Australian Veterinary Journal, 56(6):262-266.

Otte E; Kiltz HH, 1969. Anaplasmosis in Taiwan. II. Import of exotic cattle and premunition with Anaplasma centrale. Proceedings of the Annual Meeting of the United States Animal Health Association, 73:113-114.

Owen IL, 1990. Blood parasites of cattle in Papua New Guinea: a review. Papua New Guinea Journal of Agriculture, Forestry and Fisheries, 35(1-4):1-11; 45 ref.

Palmer GH, 1989. Anaplasma vaccines. Veterinary protozoan and hemoparasite vaccines., 1-29; 116 ref.

Palmer GH; Barbet AF; Kuttler KL; McGuire TC, 1986. Detection of an Anaplasma marginale common surface protein present in all stages of infection. Journal of Clinical Microbiology, 23(6):1078-1083; 32 ref.

Palmer GH; Rurangirwa FR; Kocan KM; Brown WC, 1999. Molecular basis for vaccine development against the ehrlichial pathogen Anaplasma marginale. Parasitology Today, 15(7):281-286; 44 ref.

Pangui LJ; Salifou S, 1992. Parasitological studies of tickborne haemoparasites in livestock in Benin. World Animal Review, 73(4):48-50; 4 ref.

Papadopoulos B; Brossard M; Perié NM, 1996. Piroplasms of domestic animals in the Macedonia region of Greece. 3. Piroplasms of small ruminants. Veterinary Parasitology, 63(1/2):67-74; 27 ref.

Parker RJ; Shepherd RK; Trueman KF; Jones GW; Kent AS; Polkinghorne IG, 1985. Susceptibility of Bos indicus and Bos taurus to Anaplasma marginale and Babesia bigemina infections. Veterinary Parasitology, 17(3):205-213; 17 ref.

Patarroyo JH; Villa O; Diazgranados H, 1978. Epidemiology of cattle anaplasmosis in Colombia: I. prevalence and distribution of agglutinating antibodies. Tropical Animal Health and Production, 10(3):171-174.

Paull NI; Parker RJ; Wilson AJ; Campbell RS, 1980. Epidemiology of bovine anaplasmosis in beef calves in northern Queensland. Australian Veterinary Journal, 56(6):267-271.

Payne RC; Osorio O, 1990. Tick-borne diseases of cattle in Paraguay. I. Seroepidemiological studies on anaplasmosis and babesiosis. Tropical Animal Health and Production, 22(1):53-60; 17 ref.

Payne RC; Osorio O; Ybanez A, 1990. Tick-borne diseases of cattle in Paraguay. II. Immunisation against anaplasmosis and babesiosis. Tropical Animal Health and Production, 22(2):101-108; 17 ref.

Payne RC; Scott JM, 1982. Anaplasmosis and babesiosis in El Salvador. Tropical Animal Health and Production, 14(2):75-80.

Payne RC; Waltner-Toews D; Djauhari D; Jones TW, 1991. Trypanosoma evansi infection in swamp buffalo imported into Central Java. Preventive Veterinary Medicine, 11(2):105-114; 19 ref.

Payne RC; Ward DE; Usman M; Rusli A; Djauhari D; Husein A, 1988. Prevalence of bovine haemoparasites in Aceh Province of Northern Sumatra: implications for imported cattle. Preventive Veterinary Medicine, 6(4):275-283; 17 ref.

Pena Pina J; Spross S AK, 1991. Outbreak of acute anaplasmosis in cattle with chronic copper poisoning near Mexico City. Veterinaria México, 22(1):63-67; 18 ref.

Perez E; Herrero MV; Jimenez C; Carpenter TE; Buening GB, 1994. Epidemiology of bovine anaplasmosis and babesiosis in Costa Rica. Preventive Veterinary Medicine, 20(1/2):23-31; 19 ref.

Perez E; Herrero MV; Jimenez C; Hird D; Buening GB, 1994. Effect of management and host factors on seroprevalence of bovine anaplasmosis and babesiosis in Costa Rica. Preventive Veterinary Medicine, 20(1/2):33-46; 27 ref.

Perry BD; Randolph TF, 1999. Improving the assessment of the economic impact of parasitic diseases and of their control in production animals. Veterinary Parasitology, 84(3/4):145-168; 47 ref.

Peterson KJ; Raleigh RJ; Stroud RK; Goulding RL, 1977. Bovine anaplasmosis transmission studies conducted under controlled natural exposure in a Dermacentor andersoni = (venustus) indigenous area of eastern Oregon. American Journal of Veterinary Research, 38(3):351-354.

Pham Chien; Nguyen Duc Tan; Le Duc Quyet, 1999. Results of survey on blood parasites in cattle of M'Drac district, Daklak province, Vietnam. Khoa Hoc Ky Thuat Thu Y (Veterinary Sciences and Techniques), 6(1):53-56; 5 ref.

Pipano E, 1991. Observations on the seasonal distribution of blood parasites in sheep in Israel. Israel Journal of Veterinary Medicine, 46(1):37-38; 11 ref.

Pipano E; Krigel Y; Frank M; Markovics A; Mayer E, 1986. Frozen Anaplasma centrale vaccine against anaplasmosis in cattle. British Veterinary Journal, 142(6):553-556; 9 ref.

Poncet A, 1990. Clinical aspects of anaplasmosis in cattle. Bulletin Mensuel de la Société Vétérinaire Pratique de France, 74(5):271-281; 13 ref.

Potgieter FT, 1979. Epizootiology and control of anaplasmosis in South Africa. Journal of the South African Veterinary Association, 50(4):367-372.

Potgieter FT; Rensburg Lvan, 1987. Tick transmission of Anaplasma centrale. Onderstepoort Journal of Veterinary Research, 54(1):5-7; 16 ref.

Potgieter FT; Stoltsz WH, 1994. Bovine anaplasmosis. In: Coetzer J, Thomson G, Tustin R, eds. Infectious diseases of livestock. Capetown, Oxford University Press, 408-430.

Potgieter FT; Van Rensburg L, 1983. Infectivity virulence and immunogenicity of Anaplasma centrale live blood vaccine. Onderstepoort Journal of Veterinary Research, 50(1):29-31.

Poulin E; Prunaux O; Guignard A, 1991. Anaplasmosis: results of a serological survey on the Island of Reunion. Revue de Médecine Vétérinaire, 142(3):225-227; 6 ref.

Quintana S; Liuzzi B; Fabregas B, 1992. Babesiosis-Anaplasmosis in the area of influence of the Northwest Regional Laboratory of Paysandú. 1980-1990. Veterinaria (Montevideo), 28(115):5-6, 8-12; 23 ref.

Radostits OM, Gay CG et al. , 1999. Diseases caused by rickettsia. In: Radostits OM, Gay CC, Blood DC, Hinchcliffe KW, eds. Veterinary Medicine. London, UK: WB Saunders Company Ltd, 1261-1265.

Ramprabhu R; Priya WSS; Prathaban S; Dhanapalan P, 1999. Clinical and haematological profile of anaplasmosis in goats. Indian Journal of Small Ruminants, 5(1):49-51; 7 ref.

Ramsay GC, 1997. Setting animal health priorities: A veterinary and economic analysis with special reference to the control of Babesia bovis in central Queensland. PhD thesis. Brisbane, Australia: University of Queensland.

Rao VNA; Palaniswami KS; Ghellappa DJ; Joseph SA; Gnanabaranam JF, 1991. A report of concurrent haemoprotozoan and rickettsial infections in sheep. Indian Veterinary Journal, 68(5):487-488; 10 ref.

Ray B, 1992. Report on anaplasmosis in cattle in West Bengal. Indian Journal of Animal Health, 31(1):81.

Renshaw HW, Vaughn HW et al. , 1977. Evaluation of free-roaming mule deer as carriers of anaplasmosis in an area of Idaho where bovine anaplasmosis is enzootic. Journal of the American Veterinary Medical Association, 130(3):334-339.

Ribeiro MFB; Santos JLdos; Patarroyo Salcedo JH; Faria JEde, 1984. Epidemiology of bovine anaplasmosis in Minas Gerais State. I. Prevalence of agglutinating and fluorescent antibodies in the Mata zone. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 36(4):425-432; 14 ref.

Ribeiro MFV; Reis R, 1981. Prevalencia de anaplasmose en quatro regioes do estado de Minas Gerais. Arquivos Esc. Veterinaria da Universidade Federal do Minas Gerais, 33:57-62.

Richey EJ; Palmer GH, 1990. Bovine anaplasmosis. Compendium on Continuing Education for the Practicing Veterinarian, 12(11):1661-1668; 51 ref.

Rios LGde; Aguirre DH; Gaido AB, 1990. Natural infection with Anaplasma marginale in two herds with different levels of infestation by the tick Boophilus microplus.. Revue d'élevage et de Médecine Vétérinaire des Pays Tropicaux, 43(4):447-452; 28 ref.

Ristic M, 1968. Anaplasmosis. In: Weinman D, Ristic M, eds. Infectious blood diseases of man and animals. New York, USA: Academic Press, 473-542.

Ristic M, 1981. Anaplasmosis. In: Ristic M, McIntyre I, eds. Diseases of cattle in the tropics. The Hague, Netherlands, Martinus Nijhoff.

Ristic M; Kreier JP, 1984. Family III. Anaplasmataceae Philip 1957. In: Krieg N, Holt J, eds. Bergey's Manual of systematic bacteriology. Baltimore, USA: Williams and Wilkins, 719-729.

Ristic M; Sibinovic S; Welter CJ, 1968. An attenuated Anaplasma marginale vaccine. Proceedings of the Annual Meeting of the United States Animal Health Association, 72:56-69.

Roberts RH; Love JN, 1977. Infectivity of Anaplasma marginale after ingestion by potential insect vectors. American Journal of Veterinary Research, 38(10):1629-1630.

Rodgers SJ; Welsh RD; Stebbins ME, 1994. Seroprevalence of bovine anaplasmosis in Oklahoma from 1977 to 1991. Journal of Veterinary Diagnostic Investigation, 6(2):200-206; 17 ref.

Rodriguez ON; Espaine L; Rivas A; Rodriguez P, 1989. Epidemiology of cattle diseases caused by haemoparasites in Cuba. Revista Cubana de Ciencias Veterinarias, 20(1):37-56; 22 ref.

Rodriguez ON; Rodriguez P; Espaine L; Rivas A, 1989. Frequency of haemoparasites in sheep in Cuba. Revista Cubana de Ciencias Veterinarias, 20(1):57-70; 12 ref.

Rogers RJ; Blight GW; Knott SG, 1978. A study of the epidemiology of Anaplasma marginale infections of cattle in southern Queensland: clinical disease and the prevalence of complement fixing antibodies. Australian Veterinary Journal, 54(3):115-120.

Rogers RJ; Dimmock CK; Vos AJde; Rodwell BJ, 1988. Bovine leucosis virus contamination of a vaccine produced in vivo against bovine babesiosis and anaplasmosis. Australian Veterinary Journal, 65(9):285-287; 18 ref.

Rogers RJ; Shiels IA, 1979. Epidemiology and control of anaplasmosis in Australia. Journal of the South African Veterinary Association, 50(4):363-366.

Roman Suárez HdlN, 1984. Los hemoparásitos como causa de abortos. Ciencias Técnica Agric. Veterinarias, 6:123-128.

Rosa F; Crespo MV; Dias JATS, 1998. Some ectoparasites and protozoans of cattle in the Republic of Guinea-Bissau. Garcia de Orta. Série de Zoologia, 22(1/2):59-61; [4 pl.]; 15 ref.

Sahibi H; Rhalem A; Berrag B; Goff WL, 1998. Seroprevalence of bovine anaplasmosis in Morocco. Annals of the New York Academy of Sciences, 849:427-429; 6 ref.

Santos HQ; Madruga CR; Marques APC; Queiroz RA, 1998. Prevalence of Anaplasma marginale in dairy herds of Goiania microregion by indirect fluorescent antibody technique and enzyme linked immunosorbent assay. 16th Panam. Congr. Vet. Sci., Santa Cruz de la Sierra, Spain.

Sayin F; Dyncer S; Karaer Z; cakmak A; Yukary BA; Eren H; Deger S; Nalbantoglu S, 1997. Status of the tick-borne diseases in sheep and goats in Turkey. Parassitologia (Roma), 39(2):153-156; 23 ref.

Schlichting H; Rehbein G; Merker M; Hörchner F; Sahein E, 1983. The distribution of Theileriae and Anaplasma marginale in calves in Burundi. Annales de la Société Belge de Médecine Tropicale, 63(3):259-266; 17 ref.

Schoepf K; Mustafa Mohamed HA; Katende JM, 1984. Observations on blood-borne parasites of domestic livestock in the Lower Juba region of Somalia. Tropical Animal Health and Production, 16(4):227-232; 22 ref.

Schofield LN; Saunders JR, 1987. Attempted transmission to cattle of Anaplasma marginale from overwintered Dermacentor andersoni ticks. Canadian Journal of Veterinary Research, 51(3):379-382; 18 ref.

Schroeder WF; León CE; López R, 1970. Estudio de la epizootiologia de la anaplasmosis en Venezuela por medio de la prueba de aglutinacion en tubo capilar. Boletín del instituto De Investigaciones Veterinárias, 14(29):3-14.

Serra-Freire NMda; Nuernberg S, 1995. The cattle tick and babesiosis-anaplasmosis in Santa Catarina State, Brazil. Revista Brasileira de Medicina Veterinária, 17(6):257-259; 11 ref.

Shen YinSheng, 1998. Distribution and control of haemosporidiosis in Shaanxi, China. Chinese Journal of Veterinary Medicine, 24(9):12-13.

Sherkov S; El-Rabie Y; Kokash L, 1977. A survey of parasitic blood diseases 'tickborne fever' in domestic animals in Jordan. Egyptian Journal of Veterinary Science, 13(1):29-35.

Shkap V; Bin H; Ungar-Waron H; Pipano E, 1990. An enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to Anaplasma centrale and Anaplasma marginale.. Veterinary Microbiology, 25(1):45-53; 21 ref.

Shkap V; Pipano E; McGuire TC; Palmer GH, 1991. Identification of immunodominant polypeptides common between Anaplasma centrale and Anaplasma marginale.. Veterinary Immunology and Immunopathology, 29(1-2):31-40; 23 ref.

Singh BB; Mbemba ZZ; Welu M; Butera M; Tolenga K, 1988. Epidemiological study of bovine piroplasmosis in north-eastern Zaire, particularly the north Kivu and Ituri subregions. Premières Journées Vétérinaires Africaines, Hammamet, Tunisie, 31 mai - 2 juin 1987., 127-139; 13 ref.

Siswansyah DD, 1990. Prevalence of theileriosis, babesiosis and anaplasmosis in cattle and buffaloes in South Kalimantan. Penyakit Hewan, 22(39):50-54; 5 ref.

Smith RD; Woolf A; Hungerford LL; Sundberg JP, 1982. Serologic evidence of Anaplasma marginale infection in Illinois white-tailed deer. Journal of the American Veterinary Medical Association, 181(11):1254-1256.

Solari MA, 1994. Epidemiología y prevención de los hemoparásitos (Babesia y Anaplasma) en el Uruguay. In: Fiel C, Nari A, eds. Enfermedades parasitarias de importancia económica en la Argentina y el Uruguay. Montevideo, Uruguay: Editorial Hemisferio Sur, 481-507.

Solomon G; Kaaya GP; Gebreab F; Gemetchu T; Tilahun G, 1998. Ticks and tick-borne parasites associated with indigenous cattle in Didtuyura Ranch, southern Ethiopia. Insect Science and its Application, 18(1):59-66; 31 ref.

Souza JCP; Soares CO; Madruga CR; Massard CL, 2000. Prevalência de anticorpos anti Anaplasma marginale (Ricketsiales: anaplasmatacea) em bovinos na mesoregião do Médio Paraíba. Ciência Rura, 30(4) (in press).

Spath EJA, 1986. Un estudio epidemiológico de babesiosis y anaplasmosis en el Valle de Lerma, provincia de Salta. Revista de Medicina Veterinaria Buenos Aires, 67:274-281.

Späth EJA, 1987. Estimation of the economic losses caused by bovine anaplasmosis and babesiosis in the Lerma Valley dairying area, Salta Province, Argentina. Revista de Medicina Veterinaria (Buenos Aires), 68(6):277-282,284-286; 15 ref.

Späth EJA; Guglielmone AA; Signorini AR; Mangold AJ, 1990. Estimation of the economic losses due to the tick Boophilus microplus and associated diseases in Argentina. Revista Argentina de Producción Animal, 10(Suplemento 1):76.

Srinivasan EVR; Rajendran MP; Anbumani SP, 1995. A report on the incidence of anaplasmosis in sheep in Tamil Nadu. Indian Veterinary Journal, 72(12):1307; 3 ref.

Ssenyonga GSZ; Kakoma I; Montenegro-James S; Nyeko PJ; Buga R, 1991. Anaplasmosis in Uganda. II. Prevalence of bovine anaplasmosis in Uganda. Annals of Tropical Medicine and Parasitology, 85(3):305-308; 10 ref.

Ssenyonga GSZ; Kakoma I; Nyeko JP; Buga R; Hansen R, 1992. Anaplasmosis in Uganda. III. Parasitological and serological evidence of Anaplasma infection in Ugandan goats. Onderstepoort Journal of Veterinary Research, 59(2):161-162; 8 ref.

Stauber EH; Autenrieth R; Markham OD; Whitbeck V, 1980. A seroepidemiologic survey of three pronghorn (Antilocapra americana) populations in southeastern Idaho, 1975-1977. Journal of Wildlife Diseases, 16(1):109-115.

Stewart CG; Immelman A; Grimbeek P; Grib D, 1979. The use of a short and a long acting oxytetracycline for the treatment of Anaplasma marginale in splenectomized calves. Journal of the South African Veterinary Association, 50(2):83-85.

Stiller D; Coan ME, 1995. Recent developments in elucidating tick vector relationships for anaplasmosis and equine piroplasmosis. Veterinary Parasitology, 57(1/3):97-108; 4 pp. of ref.

Stoltsz WH, 1994. Ovine and caprine anaplasmosis. In: Coetzer J, Thomson G, Tustin R, eds. Infectious diseases of livestock. Capetown, Oxford University Press, 431-438.

Su JF; Hsu FS, 1993. Serological assays and seroprevalence of ruminant Anaplasma marginale infection in Taiwan. Journal of the Chinese Society of Veterinary Science, 19(2):79-89; 20 ref.

Surendran NS; Bhaskara Rao P, 1989. Anaplasmosis in sheep in Andhra Pradesh. Indian Veterinary Journal, 66(7):672; 3 ref.

Sweet VH; Stauber EH, 1978. Anaplasmosis: a regional serologic survey and oral antibiotic therapy in infected herds. Journal of the American Veterinary Medical Association, 172(11):1310-1312.

Tapia DG; Rojas ML; Bayúgar RC; Ortiz MAG; Jalil PD; Torres RA, 1996. Serological prevalence of bovine anaplasmosis in 18 districts of northern Veracruz, Mexico. Técnica Pecuaria en México, 34(1):38-45; 21 ref.

Tarmudji; Ketaren K; Siswansyah DD; Achmad, 1990. Preliminary study on a farming system of swamp buffaloes and identification of blood parasites. Penyakit Hewan, 22(40):106-111; 9 ref.

Taylor SK; Lane VM; Hunter DL; Eyre KG; Kaufman S; Frye S; Johnson MR, 1997. Serologic survey for infectious pathogens in free-ranging American bison. Journal of Wildlife Diseases, 33(2):308-311; 13 ref.

Teclaw RF; Romo S; Garcia Z; Wagner GG, 1985. A serological survey for anaplasmosis in cattle in the Mexican states of Nuevo Leon, Tamaulipas and Coahuila using the card test. Preventive Veterinary Medicine, 3(5):417-425; 15 ref.

Theiler A, 1912. Gallsickness in imported cattle and the protective inoculation against this disease. Agricultural Journal of the Union of South Africa, 3:1-2.

Tjornehoj K; Lawrence JA; Kafuwa PT; Whiteland AP; Chimera BAR, 1997. Immunisation of smallholder dairy cattle against anaplasmosis and babesiosis in Malawi. Tropical Animal Health and Production, 29(2):77-82; 5 ref.

Tokarnia CJ; Döbereiner J, 1962. A importância da anaplasmose em nossos bezerros e as medidas de seu controle. Veterinária, 15(3-4):11-19.

Torioni de Echaide S; Knowles DP; McGuire TC; Palmer GH; Suarez CE; McElwain TF, 1998. Detection of cattle naturally infected with Anaplasma marginale in a region of endemicity by nested PCR and a competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5. Journal of Clinical Microbiology, 36(3):777-782; 45 ref.

Travassos Santos Dias JA, 1988. Veterinary parasitological survey of Timor. Garcia de Orta. Série de Zoologia, 15(2):67-88; 12 ref.

Turton JA; Katsande TC; Matingo MB; Jorgensen WK; Ushewokunze-Obatolu U; Dalgliesh RJ, 1998. Observations on the use of Anaplasma centrale for immunization of cattle against anaplasmosis in Zimbabwe. Onderstepoort Journal of Veterinary Research, 65(2):81-86; 18 ref.

Uilenberg G; Rombach MC; Perié NM; Zwart D, 1980. Blood parasites of sheep in the Netherlands. II. Babesia motasi (Sporozoa, Babesiidae). Tijdschrift Voor Diergeneeskunde, 105(2):3-14.

Uilenberg G; van Vorstenbosch CJ; Perie NM, 1979. Blood parasites of sheep in the Netherlands. I. Anaplasma mesaeterum spn. (Rickettsiales, Anaplasmataceae). Tijdschr Diergeneeskd, 104(2):14-22.

Verhulst A; Mahin L; Thys E; Witt KJde, 1983. Prevalence of antibodies to Anaplasma marginale in cattle from various African biotopes in Central Morocco, North Cameroon and South Eastern Zaire. Zentralblatt für Veterinärmedizin, B, 30(7):537-540; 7 ref.

Vidotto MC; Vidotto O; Andrade GM; Palmer G; McElwain T; Knowles DP, 1998. Seroprevalence of Anaplasma marginale in cattle in Parana State, Brazil, by MSP-5 competitive ELISA. Annals of the New York Academy of Sciences, 849:424-426; 13 ref.

Vidotto O, Yamamura MH et al. , 1995. Ocorrência de Babesia bigemina, Babesia bovis e Anaplasma marginale em rebanhos de bovinos leiteiros da região de Londrina. Revista Brasileira de Parasitologia Veterinaria, 4(2):184.

Vidotto O; Andrade GM; Amaral CHS; Barbosa CS; Freire RL; Rocha MA; Vidotto MC, 1997. Frequency of antibodies against Babesia bigemina, B. bovis and Anaplasma marginale in dairy herds in the Londrina region, Paraná State, Brazil. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 49(5):655-659; 8 ref.

Vizcaino O, Corrier DE et al. , 1980. Comparison of three methods of immunization against bovine anaplasmosis: evaluation of protection afforded against field challenge exposure. American Journal of Veterinary Research, 41(7):1066-1068.

Vos AJde; McGregor W; Stewart NP; Dalgliesh RJ; Barry DN, 1987. Influence of imidocarb prophylaxis on the pathogenicity and immunogenicity of Anaplasma marginale infections in cattle. Australian Veterinary Journal, 64(3):83-85; 15 ref.

Waldrup KA; Collisson E; Bentsen SE; Winkler CK; Wagner GG, 1989. Prevalence of erythrocytic protozoa and serologic reactivity to selected pathogens in deer in Texas. Preventive Veterinary Medicine, 7(1):49-58; 36 ref.

Wilson AJ, 1979. Observations on the pathogenesis of anaplasmosis in cattle with particular reference to nutrition, breed and age. Journal of the South African Veterinary Association, 50:293-295.

Wilson AJ; Parker R; Trueman KF, 1980. Susceptibility of Bos indicus crossbred and Bos taurus cattle to Anaplasma marginale infection. Tropical Animal Health and Production, 12(2):90-94.

Woodford JD; Gayer JG; Dolan TT; Morzaria SP, 1989. An East Coast fever immunization trial on Pemba Island, Zanzibar. Theileriosis in eastern, central and southern Africa. Proceedings of a workshop on East Coast fever immunization held in Lilongwe, Malawi 20-22 September 1988, 80-82; 1 ref.

Wright IG; Leatch G, 1996. Bovine anaplasmosis. In: Manual of standards for diagnostic tests and vaccines. Paris, France: Office International des Épizooties, 295-304.

Wu JianSan; Zhang XiaoZheng; Wu ShiYou, 1997. Detection of Anaplasma marginale DNA by using the polymerase chain reaction technique. Chinese Journal of Veterinary Science, 17(3):238-240; 5 ref.

Yilma JM; Daniel WS; Dorchies P, 1995. Survey of ticks infesting domestic ruminants in South Wollo region of Ethiopia. Revue de Médecine Vétérinaire, 146(3):213-220; 31 ref.

Zararaz HO; Parra DG, 1977. Estudio de la patogenicidad de dos cepas de Anaplasma marginale de Colombia. Revista Institituto Colombiano Agropecuario, 12(4):457-471.

Zaugg JL, 1985. Bovine anaplasmosis: transplacental transmission as it relates to stage of gestation. American Journal of Veterinary Research, 46(3):570-572; 13 ref.

Zaugg JL, 1987. Ovine anaplasmosis: in utero transmission as it relates to stage of gestation. American Journal of Veterinary Research, 48(1):100-103; 22 ref.

Zaugg JL, 1990. Seasonality of natural transmission of bovine anaplasmosis under desert mountain range conditions. Journal of the American Veterinary Medical Association, 196(7):1106-1109; 17 ref.

Zaugg JL; Kuttler KL, 1985. Anaplasma marginale infections in American bison: experimental infection and serologic study. American Journal of Veterinary Research, 46(2):438-441; 23 ref.

Distribution References

Aguirre A A, McLean R G, Cook R S, Quan T J, 1992. Serologic survey for selected arboviruses and other potential pathogens in wildlife from Mexico. Journal of Wildlife Diseases. 28 (3), 435-442.

Ahmadu B, Zulu L N K, Tuchili L M, Samui K L, 1997. The possible causes of calf mortality in Namwala district of Zambia. International Journal of Animal Sciences. 12 (1), 49-52.

Ajayi S A, Dipeolu O O, 1986. Prevalence of Anaplasma marginale, Babesia bigemina and B. bovis in Nigerian cattle using serological methods. Veterinary Parasitology. 22 (1/2), 147-149. DOI:10.1016/0304-4017(86)90017-8

Akinboade O A, Dipeolu O O, 1984. Comparison of blood smear and indirect fluorescent antibody techniques in detection of haemoparasite infections in trade cattle in Nigeria. Veterinary Parasitology. 14 (2), 95-104. DOI:10.1016/0304-4017(84)90116-X

Akinboade O A, Sadiq N A, Akinrinmade J F, Dipeolu O O, Nwufor K J, 1986. Anaplasmosis of small ruminants in Nigeria: incidence and parasite identification through blood smear and latex agglutination test (LAT). International Journal of Zoonoses. 13 (3), 210-214.

Alfaro C, Toro Benitez M, García F, Valle A, 1998. Epidemiology of bovine anaplasmosis in the state of Monagas, Venezuela. Relationship with extrinsic and intrinsic characteristics of the host. (Epidemiología de la anaplasmosis bovina en el estado Monagas. Asociación con factores extrínsecos e intrínsecos del hospedor.). Veterinaria Tropical. 23 (1), 65-79.

Alonso M, Camus E, Rodriguez Diego J, Bertaudière L, Tatareau J C, Liabeuf J M, 1992. Current position of bovine haemoparasitoses in Martinique (French West Indies). (Situation actuelle des hémoparasitoses bovines en Martinique (Antilles françaises).). Revue d'Élevage et de Médecine Vétérinaire des Pays Tropicaux. 45 (1), 9-14.

Amaral LBS, Valente FAT, 1971. (Ocorrência de moléstias nos rebanhos bovinos do Estado de São Paulo, no triênio 1965/1967. V. Piroplasmose e anaplasmose nas regiões de Campinas e Vale do Paraíba, São Paulo). In: O Biológico, 37 56-61.

Andel J M van, Dwinger R H, Alvarez J A, 1997. Study of Anaplasma and Babesia infection rates of cattle and associated ticks in the south coast of Guatemala. Revue d'Élevage et de Médecine Vétérinaire des Pays Tropicaux. 50 (4), 285-292.

Araújo F R, Madruga C R, Leal C R B, Bastos P A S, Marques A P C, 1998. Prevalence of antibodies to Anaplasma marginale in dairy herds in Bahia State, Brazil. (Freqüencia de anticorpos anti-Anaplasma marginale em rebanhos leiteiros da Bahia.). Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 50 (3), 243-246.

Artemenko L P, 1973. A study of the epizootiology and prevention of anaplasmosis in cattle in the forested regions of the Ukraine. (Dosvid vprovadzhennya kompleksu zakhodiv po borot'bi z anaplazmozom.). Veterinariya, Kiev. 91-94.

Artemko L P, 1977. Economic losses on farms where bovine anaplasmosis is endemic. Byulleten Vsesoyuznogo Instituta Eksperimental'noi Veterinarii. 42-43.

Athayde CR, Silva WW, Cavalcanti FRT, 1994. (Surto epizoótico de babesiose e anaplasmose em bovinos na região de Patos). [Anais: XXIII Congresso Brasileiro de Medicina Veterinaria, Olinda, Brazil],

Azuara LVM, Olguin YBA, Guerrero MC, 1993. (Frecuencia de anaplasmosis clínica en bovinos de dos edades diferentes en tres ranchos del municipio de Tanima en Veracruz)., Mérida, Mexico: Res. 3er Congreso Parasitología Veterinaria.

Baek B K, Chin C M, Kim B S, Kim J H, Cho C H, Rhee J M, Jung B T, 1989. Study on the antigenicity of Anaplasma marginale parasite in Korean native cattle. Korean Journal of Veterinary Public Health. 13 (3), 233-240.

Baek B K, Jin C M, Seo S Y, Seo Y W, Kim D S, Kakoma I, 1994. A study on the epidemiology of caprine anaplasmosis in Korea, I. Electron microscopic characterization of the etiologic agent. Korean Journal of Veterinary Research. 34 (2), 381-386.

Baek B K, Son K R, 1995. Study on the epidemiology of caprine anaplasmosis in Korea. III. Seasonal variation in haematological profiles. Korean Journal of Veterinary Research. 35 (1), 137-142.

Barré N, 1997. The ticks of ruminants of the Lesser Antilles: their biology, their economic importance and defensive strategies. (Les tiques des ruminants dans les Petites Antilles: biologie, importance économique, principes de lutte.). Productions Animales. 10 (1), 111-119.

Barry D M, Niekerk C H van, 1990. Anaplasmosis in improved Boer goats in South Africa artificially infected with Anaplasma ovis. Small Ruminant Research. 3 (2), 191-197. DOI:10.1016/0921-4488(90)90093-L

Behymer D E, Reimann H P, Utterback W, Elmi C D, Franti C E, 1991. Mass screening of cattle sera against 14 infectious disease agents, using an ELISA system for monitoring health in livestock. American Journal of Veterinary Research. 52 (10), 1699-1705.

Berdie J, Cardozo H, Nari A, Solari M A, Meeusen E, 1979. Prevalence of Anaplasma marginale in cattle in an area of the Rivera Department of Uruguay, as shown by the plate agglutination test. (Prevalencia de Anaplasma marginale en un area del Departamento de Rivera, mediante la prueba de aglutinacion en placa.). Veterinaria, Montevideo, Uruguay. 15 (70), 55-59.

Borko Č, 1997. Pathogenic bacteria and their tick vectors: a perfect parasitic balance? (Patogene bakterije in njihovi prenašalci klopi - dovršeno zajedavsko ravnovesje?). Veterinarske Novice. 23 (9), 305-309.

Braccini G L, Chaplin E L, Stobbe N S, Araújo F A P, Santos N R, 1992. Protozoology and rickettsial findings of the laboratory of the Veterinary Faculty of the Federal University of Rio Grande Do Sul, Brazil, 1986-1990. (Resultados de exames laboratoriais realizados no setor de protozoologia da faculdade de veterinária da Universidade Federal do Rio Grande Do Sul, Porto Alegre, nos anos 1986 a 1990.). Arquivos da Faculdade de Veterinária, UFRGS. 134-149.

Bundy D A P, Hylton G A, Wagner G G, 1983. Bovine haemoparasitic diseases in Jamaica. Tropical Animal Health and Production. 15 (1), 47-48. DOI:10.1007/BF02250762

Buriro S N, Phulan M S, Arijo A H, Memon A B, 1994. Incidence of some haemo-protozoans in Bos indicus and Bubalis bubalis in Hyderabad. Pakistan Veterinary Journal. 14 (1), 28-29.

CABI, Undated. Compendium record. Wallingford, UK: CABI

CABI, Undated a. CABI Compendium: Status inferred from regional distribution. Wallingford, UK: CABI

CABI, Undated b. CABI Compendium: Status as determined by CABI editor. Wallingford, UK: CABI

Callow LL, 1984. Arthropod-borne rickettsias of the blood. In: Animal Health in Australia, Protozoal and rickettsial diseases, [ed. by Anon]. Canberra, Australian Bureau of Animal Health, AGPS. 177-202.

Camus E, Barré N, 1995. Vector situation of tick-borne diseases in the Caribbean islands. Veterinary Parasitology. 57 (1/3), 167-176. DOI:10.1016/0304-4017(94)03118-G

Camus E, Montenegro-James S, 1994. Bovine anaplasmosis and babesiosis in the Lesser Antilles: risk assessment of an unstable epidemiologic situation. In: Veterinary Research [International Symposium on ecopathology and animal health management, Clermont-Ferrand, 18-20 October 1993.], 25 (2/3) 313-317.

Cardozo H, Solari MA, Petraccia C, Nari A, 1981. (Estudio epizootiologico de los hematozoarios transmitidos por Boophilus microplus en una area enzootica del Uruguay). In: IX Jornadas Uruguayas de Buiatria, Paysandu,

Carmichael I H, Hobday E, 1975. Blood parasites of some wild bovidae in Botswana. Onderstepoort Journal of Veterinary Research. 42 (No.2), 55-62.

Cavazzani A H, 1989. Epizootiological aspects of Anaplasma marginale in Mexico. (Aspectos epidemiologícas de la anaplasmosis en México.). FAO Animal Production and Health Paper. 310-314.

Chansiri L, 1997. Tick-borne diseases in Thailand. Tropical Animal Health and Production. 29 (4 (supplement)), 52S. DOI:10.1007/BF02632924

Chitravel V, Lourdsamy M, Ravindranath T K, Prabhakaran V, Kokilaprabhakaran S, 1998. A report on the incidence of anaplasmosis in Jersey bulls. Indian Veterinary Journal. 75 (3), 256-257.

Chomel B B, Carniciu M L, Kasten R W, Castelli P M, Work T M, Jessup D A, 1994. Antibody prevalence of eight ruminant infectious diseases in California mule and black-tailed deer (Odocoileus hemionus). Journal of Wildlife Diseases. 30 (1), 51-59.

Clark R K, Boyce W M, Jessup D A, Elliott L F, 1993. Survey of pathogen exposure among population clusters of bighorn sheep (Ovis canadensis) in California. Journal of Zoo and Wildlife Medicine. 24 (1), 48-53.

Cordoves C O, Arrieta M, Serrano E, Mesejo J, Fregel N, Fadraga M, 1989. Prognosis, surveillance and control of bovine anaplasmosis in Cuba. (Pronóstico, vigilancia y control de la anaplasmosis en la República de Cuba.). Revista Cubana de Ciencias Veterinarias. 20 (1), 17-36.

Cordovés C O, Fregel N, Camacho A, Leyva A, 1991. System for monitoring and control of haemoparasites in Cuba. (Sistema de vigilancia y control de las hemoparasitosis en la República de Cuba.). Revista Cubana de Ciencias Veterinarias. 22 (3), 197-232.

Corrier D E, Guzman S, 1977. The effect of natural exposure to Anaplasma and Babesia infections on native calves in an endemic area of Colombia. Tropical Animal Health and Production. 9 (1), 47-51. DOI:10.1007/BF02297391

Corrier D E, Kuttler K L, Terry M K, 1983. Observations on anaplasmosis following field exposure to heavy and light infestations with Boophilus microplus. Veterinary Parasitology. 13 (2), 187-190. DOI:10.1016/0304-4017(83)90079-1

Cossío-Bayúgar R, Rodríguez S D, García-Ortiz M A, García-Tapia D, Aboytes-Torres R, 1997. Bovine anaplasmosis prevalence in northern Veracruz state, Mexico. Preventive Veterinary Medicine. 32 (3/4), 165-170. DOI:10.1016/S0167-5877(97)00016-0

Dalagnol CA, Martins E, Madruga CR, 1995. (Prevalência de anticorpos contra Babesia bovis, Babesia bigemina, Anaplasma marginale em bovinos de corte na região de clima Cfb). In: Revista Brasileira de Parasitologia Veterinaria, 4 (2) 220.

Deem S L, Perry B D, Katende J M, McDermott J J, Mahan S M, Maloo S H, Morzaria S P, Musoke A J, Rowlands G J, 1993. Variations in prevalence rates of tick-borne diseases in Zebu cattle by agroecological zone: implications for East Coast fever immunization. Preventive Veterinary Medicine. 16 (3), 171-187. DOI:10.1016/0167-5877(93)90064-Z

Delgado A, Fernadez A, Fregel N, 1976. (Anaplasmose et piroplasmose bovines. Considérations épizootiologiques et mesures de lutte dans la République de Cuba). In: Bulletin de L'Office International des Epizootics, 86 117-121.

Dissamarn R, Aranyakananda P, Thirapat K, 1968. Anaplasmosis and the prophylactic measures in Thailand. In: Bulletin of Epizootic Diseases of Africa, 16 (1) 65-70.

Dreyer K, Fourie L J, Kok D J, 1998. Epidemiology of tick-borne diseases of cattle in Botshabelo and Thaba Nchu in the Free State Province. Onderstepoort Journal of Veterinary Research. 65 (4), 285-289.

Egbe-Nwiyi T N, Salako M A, Otukonyong E E, 1997. Observations on naturally occurring bovine anaplasmosis in arid zone of North-Eastern Nigeria: prevalence, haematological and pathological changes. Studies and Researches in Veterinary Medicine. 95-99.

Elliott L F, Boyce W M, Clark R K, Jessup D A, 1994. Geographic analysis of pathogen exposure in bighorn sheep (Ovis canadensis). Journal of Wildlife Diseases. 30 (3), 315-318.

El-Metenawy T M, 2000. Prevalence of blood parasites among cattle at the central area of Saudi Arabia. Veterinary Parasitology. 87 (2/3), 231-236. DOI:10.1016/S0304-4017(99)00158-2

El-Seify M A, Eissa N A, 1990. Some clinico-pathological studies on cattle naturally infected with blood parasites in Beni-Suef Governorate. Egyptian Journal of Comparative Pathology and Clinical Pathology. 3 (1), 37-43.

Ewing S A, Panciera R J, Kocan K M, Ge N L, Welsh R D, Olson R W, Barker R W, Rice L E, 1997. A winter outbreak of anaplasmosis in a nonendemic area of Oklahoma: a possible role for Dermacentor albipictus. Journal of Veterinary Diagnostic Investigation. 9 (2), 206-208.

Fadraga M, Cordovés C O, Puentes T, 1991. Circulation of antibodies to haemoparasites in cattle (Bos taurus) of high genetic value in Cuba. (Circulación de anticuerpos de hemoparásitos en ganado (Bos taurus) de alto valor genético en la República de Cuba.). Revista Cubana de Ciencias Veterinarias. 22 (3), 249-255.

Fanikiso M, Ndzinge I T, 1992. Situation report on tick infestation of livestock, tick-borne disease and tick control methods in Botswana. Insect Science and its Application. 13 (4), 645-648.

Fragoso Sánchez H, 1991. (La anaplasmosis bovina en México). In: 2do Sem. Int. Parasitol, Oaxtepec, Mexico: 153-160.

Franzolin Neto R, Porto A, Lacaz Ruiz R, 1989. Anaplasmosis and babesiosis: a clinical case in buffalo (Bubalus bubalis) calf in Brazil. In: Buffalo Bulletin, 8 (3)

Ge NieLin, Kocan K M, Ewing S A, Blouin E F, Edwards W L, Murphy G L, Dawson L J, 1997. Use of a non-radioactive DNA probe for detection of Anaplasma marginale infection in field cattle: comparisons with complement fixation serology and microscopic examination. Journal of Veterinary Diagnostic Investigation. 9 (1), 39-43.

Gitau G K, Perry B D, Katende J M, McDermott J J, Morzaria S P, Young A S, 1997. The prevalence of serum antibodies to tick-borne infections in cattle in smallholder dairy farms in Murang'a District, Kenya; a cross-sectional study. Preventive Veterinary Medicine. 30 (2), 95-107. DOI:10.1016/S0167-5877(96)01100-2

Gloss RM, 1964. (Experiências com o Anaplasma centrale com finalidade de facilitar o serviço de premunição). In: Anais: III Conferência da SOVERGS, Porto Alegre, 65-71.

Goff W L, Winward L D, 1985. Detection of geographic isolates of Anaplasma marginale, using polyclonal bovine antisera and microfluorometry. American Journal of Veterinary Research. 46 (11), 2399-2400.

Guglielmone A A, 1995. Epidemiology of babesiosis and anaplasmosis in South and Central America. Veterinary Parasitology. 57 (1/3), 109-119. DOI:10.1016/0304-4017(94)03115-D

Guglielmone A A, Abdala A A, Anziani O, Mangold A J, Volpogni M M, Vanzini V R, 1997. Different seasonal occurrence of anaplasmosis outbreaks in beef and dairy cattle in an area of Argentina free of Boophilus microplus ticks. Veterinary Quarterly. 19 (1), 32-33.

Guglielmone AA, 1994. (Epidemiología y control de los hemoparásitos (Babesia y Anaplasma) de los vacunos en la Argentina). In: Enfermedades parasitarias de importancia económica en la Argentina y el Uruguay, [ed. by Fiel C, Nari A]. Montevideo, Editorial Hemisferio Sur. 461-479.

Guido M C, Dell'Porto A, Fujii T U, Artes R, 1994. Prevalence of hemoparasites in buffaloes from Ribeira Valley, south coast of São Paulo state - Brazil. In: Proceedings 4th World Buffalo Congress, Sao Paulo, Brazil, 27-30 June, 1994: Volume 2. [Proceedings 4th World Buffalo Congress, Sao Paulo, Brazil, 27-30 June, 1994: Volume 2.], 325-327.

Ha Thuy Hanh, Nguyen Dang Khai, Pham Sy Lang, Phan Dich Lan, Nguyen Duc Tan, Hoang Manh Lam, 1997. Blood parasites of cattle in Daklak province, Vietnam. (Mot so nhan xet ve tinh hinh nhiem cac bao tu trung mau (haemosporidia) o bo tinh Dac Lac.). Khoa Hoc Ky Thuat Thu Y. 4 (4), 50-53.

Hashemi-Fesharki R, 1997. Tick-borne diseases of sheep and goats and their related vectors in Iran. In: Parassitologia (Roma) [Proceedings of the FAO Expert Consultation on ticks and tick-borne diseases of sheep and goats, Rome, Italy, 29-30 September 1994.], 39 (2) [ed. by Maroli M, Ghirotti M, De Castro J J]. 115-117.

Hidalgo R J, Palmer G H, Jones E W, Brown J E, Ainsworth A J, 1989. Infectivity and antigenicity of Anaplasma marginale from tick cell culture. American Journal of Veterinary Research. 50 (12), 2033-2036.

Horn S, 1983. (Prováveis prejuízos causados pelos carrapatos)., Brasília: Bol. Defesa Sanitária Animal, No. Especial.

Hugh-Jones M E, Hubbert W, 1988. Seroconversion rates to bovine leukosis virus, bluetongue virus, Leptospira hardjo and Anaplasma marginale infections in a random series of Louisiana beef cattle. Acta Veterinaria Scandinavica. 107-109.

Hungerford L L, Smith R D, 1996. Spatial and temporal patterns of bovine anaplasmosis as reported by Illinois veterinarians. Preventive Veterinary Medicine. 25 (3/4), 301-313. DOI:10.1016/0167-5877(95)00507-2

Hungerford L L, Smith R D, 1997. Variations in seroprevalence and host factors for bovine anaplasmosis in Illinois. Veterinary Research Communications. 21 (1), 9-18. DOI:10.1023/B:VERC.0000009696.68224.a8

Ilemobade A A, 1992. Anaplasmosis, babesiosis and cowdriosis in the West African sub-region: distribution, economic importance and control measures. In: Recent developments in the control of anaplasmosis, babesiosis and cowdriosis, [ed. by Dolan T T]. Nairobi, Kenya: International Laboratory for Research on Animal Diseases. 43-47.

James M A, Coronado A, Lopez W, Melendez R, Ristic M, 1985. Seroepidemiology of bovine anaplasmosis and babesiosis in Venezuela. Tropical Animal Health and Production. 17 (1), 9-18. DOI:10.1007/BF02356127

Jessup D A, Goff W L, Stiller D, Oliver M N, Bleich V C, Boyce W M, 1993. A retrospective serologic survey for Anaplasma spp. infection in three bighorn sheep (Ovis canadensis) populations in California. Journal of Wildlife Diseases. 29 (4), 547-554.

Jithendran K P, 1997. Blood protista of cattle and buffaloes in Kangra Valley, Himachal Pradesh. Indian Journal of Animal Sciences. 67 (3), 207-208.

Jongejan F, Perry B D, Moorhouse P D S, Musisi F L, Pegram R G, Snacken M, 1988. Epidemiology of bovine babesiosis and anaplasmosis in Zambia. Tropical Animal Health and Production. 20 (4), 234-242. DOI:10.1007/BF02239989

Jorgensen W K, Weilgama D J, Navaratne M, Dalgliesh R J, 1992. Prevalence of Babesia bovis and Anaplasma marginale at selected localities in Sri Lanka. Tropical Animal Health and Production. 24 (1), 9-14. DOI:10.1007/BF02357227

Jorgensen W, Weilgama D J, Navaratne M, Weerasinghe C, Perera P S G, 1988. Observations on the prevalence of Babesia and Anaplasma infections in some Government livestock farms in Sri Lanka. In: Sri Lanka Veterinary Journal, 36 56-57.

Kabagambe J, Nshimiyimana A, Muberuka J, Nyiligira J B, 1988. The enzootic diseases of cattle at Bugesera. (Lés maladies enzootiques des bovins au Bugesera.). Bulletin Agricole du Rwanda. 21 (3), 159-168.

Keirans J E, Hutcheson H J, Durden L A, Klompen J S H, 1996. Ixodes (Ixodes) scapularis (Acari: Ixodidae): redescription of all active stages, distribution, hosts, geographical variation, and medical and veterinary importance. Journal of Medical Entomology. 33 (3), 297-318. DOI:10.1093/jmedent/33.3.297

Kessler R E, Sastre A M, Moreira M A, Madruga C R, Honer M R, 1991. Experiments in Brazil with live attenuated vaccines for Babesia bovis, B. bigemina, Anaplasma marginale and A. centrale preserved by freezing. (Experiencias con vacunas vivas atenuadas de Babesia bovis, B. bigemina, Anaplasma marginale y A. centrale conservadas por congelación en Brasil.). Revista Cubana de Ciencias Veterinarias. 22 (3), 189-196.

Kessler R H, Madruga C R, Fabrício de Jesus E, Semprebom D V, 1987. Isolation of pure strains of Babesia bovis, Babesia bigemina and Anaplasma marginale from cattle in an enzootic area. (Isolamento de cepas puras de Babesia bovis, Babesia bigemina e Anaplasma marginale em área enzoótica.). Pesquisa Agropecuária Brasileira. 22 (6), 747-752.

Kocan K M, 1994. Anaplasmosis in Oklahoma and the South Central United States. Proceedings of the United States Animal Health Association. 216-222.

Kuttler KL, Adams LG, Zaraza H, 1970. (Estudio epizotiológico del Anaplasma marginale y del Trypanosoma theileri en Colombia). In: Revista Institituto Colombiano Agropecuario, 5 127-148.

Latif A A, Rowlands G J, Punyua D K, Hassan S M, Capstick P B, 1995. An epidemiological study of tick-borne diseases and their effects on productivity of zebu cattle under traditional management on Rusinga Island, western Kenya. Preventive Veterinary Medicine. 22 (3), 169-181. DOI:10.1016/0167-5877(94)00408-B

Lawrence J A, Musisi F L, Mfitilodze M W, Tjornehoj K, Whiteland A P, Kafuwa P T, Chamambala K E, 1996. Integrated tick and tick-borne disease control trials in crossbred dairy cattle in Malawi. Tropical Animal Health and Production. 28 (4), 280-288. DOI:10.1007/BF02240818

Lawrence J A, Norval R A I, 1987. A history of ticks and tick-borne diseases of cattle in Rhodesia. Historia Medicinae Veterinariae. 12 (4), 89-101.

Lee JooMook, Kwon OhDeog, Song HeeJong, Park JinHo, Choi KyoungSeong, 1997. Anaplasma marginale infection in Holstein calves during winter. Korean Journal of Veterinary Research. 37 (4), 911-916.

Levasseur G, 1991. Bovine babesiosis in France. Bovine anaplasmosis. (Babésiose bovine en France. Anaplasmose bovine.). Bulletin des G.T.V. 163-169.

Lora C A, Koechlin A, 1969. An attenuated Anaplasma marginale vaccine in Peru. American Journal of Veterinary Research. 1993-1998.

Lu WenShun, Lu WenXiang, Zhang QiCai, Yu Feng, Dou HuiFang, Yin Hong, 1997. Ovine anaplasmosis in northwest China. Tropical Animal Health and Production. 29 (4 (supplement)), 16S-18S.

Lu WenXiang, Lu WanShun, Zhang QiCai, Luo JianXun, Yin Hong, Dou HuiFang, 1995. Survey of the species of tick-transmitted haemocytozoa of cattle and the distribution features in China. Chinese Journal of Veterinary Science and Technology. 25 (8), 13-16.

Maas J, Buening G M, Porath W, 1981. Serologic evidence of Anaplasma marginale infection in white-tailed deer (Odocoileus virginianus) in Missouri. Journal of Wildlife Diseases. 17 (1), 45-47.

Maas J, Lincoln S D, Coan M E, Kuttler K L, Zaugg J L, Stiller D, 1986. Epidemiologic aspects of bovine anaplasmosis in semiarid range conditions of south central Idaho. American Journal of Veterinary Research. 47 (3), 528-533.

Madruga C R, Aycardi E, Putt N, 1983. Epidemiology of bovino anaplasmosis and babesiosis in the Savannah region of the Mato Grosso do Sul State (Brazil). I. Prevalence. (Epidemiologia da anaplasmose e babesiose em bovinos da Região de cerrado do estado de Mato Grosso do Sul. I. Prevalencia.). Arquivo Brasileiro de Medicina Veterinaria e Zootecnia. 35 (5), 631-640.

Madruga C R, Honer M R, Schenk M A M, Curvo J B E, 1987. Preliminary analysis of epidemiological parameters of tickborne diseases of cattle in Mato Grosso do Sul. (Avaliação preliminar de parâmetros epidemiolôgicos da tristeza parasitária bovina no Mato Grosso do Sul.). In: Pesquisa em Andamento, Centro Nacional de Pesquisa de Gado de Corte, EMBRAPA, Brazil, 7 pp.

Madruga C R, Kessler R H, Gomes A, Schenk M A M, Andrade D F de, 1985. Levels of antibodies and Anaplasma marginale parasitaemia in Nelore, Ibage and Nelore crossbred calves in an endemic area. (Niveis de anticorpos e parasitemia de Anaplasma marginale em area enzootica, nos bezerros da raca Nelore, Ibage e cruzamentos de Nelore.). Pesquisa Agropecuária Brasileira. 20 (1), 135-142.

Madruga CR, Gomes RF, Shenk MAM, 1984. (Etiologia de algumas doenças de bezerros de corte no estado de Mato Grosso do Sul)., Campo Grande, Brazil: EMBRAPA-CNPGC.

Magonigle R A, Eckblad W P, Lincoln S D, Frank F W, 1981. Anaplasma ovis in Idaho sheep. American Journal of Veterinary Research. 42 (2), 199-201.

Majaj-Büscher H, 1992. Ectoparasites and blood parasites of goats in Jordan. (Untersuchungen zum Befall von Ziegen mit Ektoparasiten und Blutparasiten in Jordanien.). Germany: Fachbereich Veterinärmedizin, Freie Universität, Berlin. 119 pp.

Marutyan E M, Zaratsyan A A, 1986. Epizootic course of bovine anaplasmosis in Armenia. Veterinariya, Moscow, USSR. 46-47.

Massard CL, 1986. (Progresos en las investigaciones de hemoparásitos en la UFRJ,). In: Rio de Janeiro. 2do Seminário Garrapatas, enfermedades transmitidas por e insectos nocivos para los bovinos en los países sudamericanos del cono sur, Porot Alegre, Brazil,

Mattioli R C, Bah M, Faye J, Kora S, Cassama M, 1993. A comparison of field tick infestation on N'Dama, zebu and N'Dama×zebu crossbred cattle. Veterinary Parasitology. 47 (1-2), 139-148. DOI:10.1016/0304-4017(93)90184-O

Mattioli R C, Janneh L, Corr N, Faye J A, Pandey V S, Verhulst A, 1997. Seasonal prevalence of ticks and tick-transmitted haemoparasites in traditionally managed N'Dama cattle with reference to strategic tick control in the Gambia. Medical and Veterinary Entomology. 11 (4), 342-348. DOI:10.1111/j.1365-2915.1997.tb00420.x

McGinnis B, Zingeser J, Grant G, Hugh-Jones M E, 1988. Bovine anaplasmosis in Jamaica. Tropical Animal Health and Production. 20 (1), 42-44. DOI:10.1007/BF02239644

Mekonnen S, Castro J, Gebre S, Hussein I, Regassa A, 1992. Ticks, tick-borne diseases and their control in western Ethiopia. Insect Science and its Application. 13 (4), 661-664.

Meléndez R D, Forlano M, 1997. Seroprevalence and incidence of babesiosis and anaplasmosis in a Carora breed herd from Venezuela. Revista Brasileira de Parasitologia Veterinária. 6 (2), 105-109.

Melo MAD, Rocha JMD, Alves LC, 1993. (Diagnóstico da situacao da anaplasmose bovina no município de Garanhuns/Pernambuco). In: Revista Brasileira de Parasitologia Veterinaria, 2 (1) 103.

Melo VSP, Passos LMF, Facury Filho EJ, Ribeiro MFB, 1999. (Infecao natural por Anaplasma marginale em bezerras de fazendas leiteiras da regiao Metalúrgica de Minas Gerais). In: An. 11. Seminário Brasileiro de Parasitologia Veterinária, Salvador, Brazil: 243-244.

Miranpuri G S, 1988. Ticks parasitizing the Indian buffalo (Bubalus bubalis) and their possible role in disease transmission. Veterinary Parasitology. 27 (3-4), 357. DOI:10.1016/0304-4017(88)90050-7

Mirón CA, 1978. (Prevalencia de la anaplasmosis bovina en el departamento de San Miguel). In: Agric. El Salvador, 17 12-24.

Misraulia K S, Sisodia R S, Mehta H K, 1988. Incidence of anaplasmosis in exotic and crossbred cattle in and around Indore and Mhow, Madhya Pradesh. Indian Veterinary Journal. 65 (7), 574-576.

Mohan RN, Pathak RC, 1967. Prevalence of anaplasmosis in ruminants in Northern India. In: American Journal of Veterinary Research, 28 (123) 599-601.

Molina J, Montenegro M, 1997. Case report - Anaplasmosis in two Philippine cows. In: Philippine Journal of Veterinary Medicine, 26 (1-2) 181-187.

Morel PC, 1967. (Etude sur les tiques du bétail en Guadeloupe et Martinique. II. Agents pathogèns transmis par les tiques). In: Revue D Élevage et de Médecine Véterinaire des Pays Tropicaux, 20 291-299.

Ndarathi C M, Waghela S, Semenye P P, 1989. Prevalence of ticks on rangeland domestic ruminants in Kajiado district, Kenya. Bulletin of Animal Health and Production in Africa. 37 (3), 209-212.

Ndung'u L W, Aguirre C, Rurangirwa F R, McElwain T F, McGuire T C, Knowles D P, Palmer G H, 1995. Detection of Anaplasma ovis infection in goats by major surface protein 5 competitive inhibition enzyme-linked immunosorbent assay. Journal of Clinical Microbiology. 33 (3), 675-679.

Nguyen Van Hau, Nhu Van Thu, Ha Thuy Hanh, Le Minh Sat, 1999. A preliminary study on application of polymerase chain reaction in diagnosis of haemosporidiosis in cattle. Khoa Hoc Ky Thuat Thu Y (Veterinary Sciences and Techniques). 6 (1), 48-52.

Nicholls M J, Ibata G, Rodas F V, 1980. Prevalence of antibodies to Babesia bovis and Anaplasma marginale in dairy cattle in Bolivia. Tropical Animal Health and Production. 12 (1), 48-49. DOI:10.1007/BF02242630

Nogueira F R C, Massard C L, Barreira J D, 1991. Parasitic diseases of cattle. Epidemiology, clinical signs, diagnosis, control measures and prophylaxis. (Tristeza parasitária bovina. Epidemiologia sinais clínicos, diagnóstico, medidas de controle e profilaxia.). In: Circular Técnica - Empresa de Pesquisa Agropecuária do Estado do Rio de Janeiro, 12 5-14.

Norval R A I, Fivaz B H, Lawrence J A, Brown A F, 1984. Epidemiology of tick-borne diseases of cattle in Zimbabwe. II. Anaplasmosis. Tropical Animal Health and Production. 16 (2), 63-70. DOI:10.1007/BF02239846

OIE Handistatus, 2005. World Animal Health Publication and Handistatus II (dataset for 2004)., Paris, France: Office International des Epizooties.

OIE, 2012. World Animal Health Information Database. Version 2., Paris, France: World Organisation for Animal Health. https://www.oie.int/wahis_2/public/wahid.php/Wahidhome/Home

Oliveira A A de, Padreira P A S, Almeida M F R S de, 1992. Calf diseases. II. Epidemiology of anaplasmosis in the state of Sergipe. (Doenças de bezerros. II. Epidemiologia da anaplasmose no estado de Sergipe.). Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 44 (5), 377-386.

Oliveira JB, Madruga CR, Schenck MAM, Massard CL, 1999. (Caracterização antigênica de isolados de Anaplasma marginale dos Estados de Pernambuco e Mato Grosso do Sul)., Salvador, Anais do XI Seminário Brasileiro de Parasitologia Veterinária. 245-246.

Osman A M, 1997. Major tick-borne diseases of sheep and goats in the Sudan. In: Parassitologia (Roma) [Proceedings of the FAO Expert Consultation on ticks and tick-borne diseases of sheep and goats, Rome, Italy, 29-30 September 1994.], 39 (2) [ed. by Maroli M, Ghirotti M, De Castro J J]. 143-144.

Otte E, Kiltz HH, 1969. Anaplasmosis in Taiwan. II. Import of exotic cattle and premunition with Anaplasma centrale. [Proceedings of the Annual Meeting of the United States Animal Health Association], 73 113-114.

Owen I L, 1990. Blood parasites of cattle in Papua New Guinea: a review. Papua New Guinea Journal of Agriculture, Forestry and Fisheries. 35 (1-4), 1-11.

Palmer G H, 1989. Anaplasma vaccines. In: Veterinary protozoan and hemoparasite vaccines. [ed. by Wright I G]. Boca Raton, Florida, USA: CRC Press, Inc. 1-29.

Palmer G H, Barbet A F, Kuttler K L, McGuire T C, 1986. Detection of an Anaplasma marginale common surface protein present in all stages of infection. Journal of Clinical Microbiology. 23 (6), 1078-1083.

Pangui L J, Salifou S, 1992. Parasitological studies of tickborne haemoparasites in livestock in Benin. (Enquêtes parasitologiques sur les hémoparasites des bovins transmis par les tiques au Bénin.). World Animal Review. 73 (4), 48-50.

Papadopoulos B, Brossard M, Perié N M, 1996. Piroplasms of domestic animals in the Macedonia region of Greece. 3. Piroplasms of small ruminants. Veterinary Parasitology. 63 (1/2), 67-74. DOI:10.1016/0304-4017(95)00846-2

Patarroyo J H, Villa O, Diazgranados H, 1978. Epidemiology of cattle anaplasmosis in Colombia: I. Prevalence distribution of agglutinating antibodies. Tropical Animal Health and Production. 10 (3), 171-174. DOI:10.1007/BF02235334

Payne R C, Osorio O, 1990. Tick-borne diseases of cattle in Paraguay. I. Seroepidemiological studies on anaplasmosis and babesiosis. Tropical Animal Health and Production. 22 (1), 53-60. DOI:10.1007/BF02243500

Payne R C, Scott J M, 1982. Anaplasmosis and babesiosis in El Salvador. Tropical Animal Health and Production. 14 (2), 75-80. DOI:10.1007/BF02282584

Payne R C, Waltner-Toews D, Djauhari D, Jones T W, 1991. Trypanosoma evansi infection in swamp buffalo imported into Central Java. Preventive Veterinary Medicine. 11 (2), 105-114. DOI:10.1016/S0167-5877(05)80032-7

Payne R C, Ward D E, Usman M, Rusli A, Djauhari D, Husein A, 1988. Prevalence of bovine haemoparasites in Aceh Province of Northern Sumatra: implications for imported cattle. Preventive Veterinary Medicine. 6 (4), 275-283. DOI:10.1016/0167-5877(88)90039-6

Peña Piña J, Spross S A K, 1991. Outbreak of acute anaplasmosis in cattle with chronic copper poisoning near Mexico City. (Anaplasmosis e intoxicación crónica por cobre en bovinos del Altiplano de México.). Veterinaria México. 22 (1), 63-67.

Peterson K J, Raleigh R J, Stroud R K, Goulding R L, 1977. Bovine anaplasmosis transmission studies conducted under controlled natural exposure in a Dermacentor andersoni = (venustus) indigenous area of eastern Oregon. American Journal of Veterinary Research. 38 (3), 351-354.

Pham Chien, Nguyen Duc Tan, Le Duc Quyet, 1999. Results of survey on blood parasites in cattle of M'Drac district, Daklak province, Vietnam. Khoa Hoc Ky Thuat Thu Y (Veterinary Sciences and Techniques). 6 (1), 53-56.

Pipano E, 1991. Observations on the seasonal distribution of blood parasites in sheep in Israel. Israel Journal of Veterinary Medicine. 46 (1), 37-38.

Poncet A, 1990. Clinical aspects of anaplasmosis in cattle. (Aspects cliniques de l'anaplasmose bovine.). Bulletin Mensuel de la Société Vétérinaire Pratique de France. 74 (5), 271-281.

Potgieter F T, 1979. Epizootiology and control of anaplasmosis in South Africa. Journal of the South African Veterinary Association. 50 (4), 367-372.

Poulin E, Prunaux O, Guignard A, 1991. Anaplasmosis: results of a serological survey on the Island of Reunion. (L'anaplasmose: résultats d'une enquête sérologique sur l'Ile de la Réunion.). Revue de Médecine Vétérinaire. 142 (3), 225-227.

Quintana S, Liuzzi B, Fabregas B, 1992. Babesiosis-Anaplasmosis in the area of influence of the Northwest Regional Laboratory of Paysandú. 1980-1990. (Babesiosis-Anaplasmosis en el área de acción del Laboratorio Regional Noroeste Paysandú. Período: 1980-1990.). Veterinaria (Montevideo). 28 (115), 5-6, 8-12.

Ramprabhu R, Priya W S S, Prathaban S, Dhanapalan P, 1999. Clinical and haematological profile of anaplasmosis in goats. Indian Journal of Small Ruminants. 5 (1), 49-51.

Rao V N A, Palaniswami K S, Ghellappa D J, Joseph S A, Gnanabaranam J F, 1991. A report of concurrent haemoprotozoan and rickettsial infections in sheep. Indian Veterinary Journal. 68 (5), 487-488.

Ray B, 1992. Report on anaplasmosis in cattle in West Bengal. Indian Journal of Animal Health. 31 (1), 81.

Ribeiro M F B, Reis R, 1981. [I] Prevalence of anaplasmosis in four regions of Minas Gerais State, Brazil. [II] Natural exposure of calves to Anaplasma marginale in endemic areas of Minas Gerais State, Brazil. ((I) Prevalencia da anaplasmose em quatro regioes do Estado de Minas Gerais. (II) Exposicao natural de bezerros, em area endemica de Anaplasma marginale, de Minas Gerais.). Arquivos da Escola de Veterinaria da Universidade Federal de Minas Gerais. 33 (1), 57-66.

Ribeiro M F B, Santos J L dos, Patarroyo Salcedo J H, Faria J E de, 1984. Epidemiology of bovine anaplasmosis in Minas Gerais State. I. Prevalence of agglutinating and fluorescent antibodies in the Mata zone. (Epidemiologia da anaplasmose bovina no Estado de Minas Gerais. I. Prevalencia de anticorpos aglutinantes e fluorescentes na Zona da Mata.). Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 36 (4), 425-432.

Rios L G de, Aguirre D H, Gaido A B, 1990. Natural infection with Anaplasma marginale in two herds with different levels of infestation by the tick Boophilus microplus. (Infection naturelle par Anaplasma marginale chez deux troupeaux de bovins avec différents niveaux d'infestation par la tique Boophilus microplus.). Revue d'Élevage et de Médecine Vétérinaire des Pays Tropicaux. 43 (4), 447-452.

Rodgers S J, Welsh R D, Stebbins M E, 1994. Seroprevalence of bovine anaplasmosis in Oklahoma from 1977 to 1991. Journal of Veterinary Diagnostic Investigation. 6 (2), 200-206.

Rogers R J, Blight G W, Knott S G, 1978. A study of the epidemiology of Anaplasma marginale infections of cattle in southern Queensland: clinical disease and the prevalence of complement fixing antibodies. Australian Veterinary Journal. 54 (3), 115-120. DOI:10.1111/j.1751-0813.1978.tb05521.x

Roman Suárez HdlN, 1984. (Los hemoparásitos como causa de abortos). In: Ciencias Técnica Agric. Veterinarias, 6 123-128.

Santos HQ, Madruga CR, Marques APC, Queiroz RA, 1998. Prevalence of Anaplasma marginale in dairy herds of Goiania microregion by indirect fluorescent antibody technique and enzyme linked immunosorbent assay., Santa Cruz de la Sierra, Spain: 16th Panam. Congr. Vet. Sci.

Schoepf K, Mustafa Mohamed H A, Katende J M, 1984. Observations on blood-borne parasites of domestic livestock in the Lower Juba region of Somalia. Tropical Animal Health and Production. 16 (4), 227-232. DOI:10.1007/BF02265329

Schofield L N, Saunders J R, 1987. Attempted transmission to cattle of Anaplasma marginale from overwintered Dermacentor andersoni ticks. Canadian Journal of Veterinary Research. 51 (3), 379-382.

Schroeder WF, León CE, López R, 1970. (Estudio de la epizootiologia de la anaplasmosis en Venezuela por medio de la prueba de aglutinacion en tubo capilar). In: Boletín del instituto De Investigaciones Veterinárias, 14 (29) 3-14.

Serra-Freire N M da, Nuernberg S, 1995. The cattle tick and babesiosis-anaplasmosis in Santa Catarina State, Brazil. (O carrapato e a tristeza parasitária bovina no Estado de Santa Catarina, Brasil.). Revista Brasileira de Medicina Veterinária. 17 (6), 257-259.

Shen YinSheng, 1998. Distribution and control of haemosporidiosis in Shaanxi, China. Chinese Journal of Veterinary Medicine. 24 (9), 12-13.

Sherkov S, El-Rabie Y, Kokash L, 1977. A survey of parasitic blood diseases 'tickborne fever' in domestic animals in Jordan. In: Egyptian Journal of Veterinary Science, 13 (1) 29-35.

Shkap V, Bin H, Ungar-Waron H, Pipano E, 1990. An enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to Anaplasma centrale and Anaplasma marginale. Veterinary Microbiology. 25 (1), 45-53. DOI:10.1016/0378-1135(90)90092-A

Shkap V, Pipano E, McGuire T C, Palmer G H, 1991. Identification of immunodominant polypeptides common between Anaplasma centrale and Anaplasma marginale. Veterinary Immunology and Immunopathology. 29 (1-2), 31-40. DOI:10.1016/0165-2427(91)90050-M

Siswansyah D D, 1990. Prevalence of theileriosis, babesiosis and anaplasmosis in cattle and buffaloes in South Kalimantan. (Prevalensi theileriosis, babesiosis dan anaplasmosis pada sapi dan kerbau di Kalimantan Selatan.). Penyakit Hewan. 22 (39), 50-54.

Smith R D, Woolf A, Hungerford L L, Sundberg J P, 1982. Serologic evidence of Anaplasma marginale infection in Illinois white-tailed deer. Journal of the American Veterinary Medical Association. 181 (11), 1254-1256.

Solari MA, 1994. (Epidemiología y prevención de los hemoparásitos (Babesia y Anaplasma) en el Uruguay). In: Enfermedades parasitarias de importancia económica en la Argentina y el Uruguay, [ed. by Fiel C, Nari A]. Montevideo, Uruguay: Editorial Hemisferio Sur. 481-507.

Solomon G, Kaaya G P, Gebreab F, Gemetchu T, Tilahun G, 1998. Ticks and tick-borne parasites associated with indigenous cattle in Didtuyura Ranch, southern Ethiopia. Insect Science and its Application. 18 (1), 59-66.

Souza JCP, Soares CO, Madruga CR, Massard CL, 2000. (Prevalência de anticorpos anti Anaplasma marginale (Ricketsiales: anaplasmatacea) em bovinos na mesoregião do Médio Paraíba). In: Ciência Rura, 30 (4)

Späth E J A, 1987. Estimation of the economic losses caused by bovine anaplasmosis and babesiosis in the Lerma Valley dairying area, Salta Province, Argentina. (Estimación de las pérdidas económicas producidas por la anaplasmosis y babesiosis bovina en la cuenca lechera del Valle de Lerma, Provincia de Salta.). Revista de Medicina Veterinaria (Buenos Aires). 68 (6), 277-282,284-286.

Späth E J A, Guglielmone A A, Signorini A R, Mangold A J, 1990. Estimation of the economic losses due to the tick Boophilus microplus and associated diseases in Argentina. (Estimación de las perdidas económicas producidas por la garrapata Boophilus microplus y las enfermedades asociadas en la Argentina.). Revista Argentina de Producción Animal. 10 (Suplemento 1), 76.

Srinivasan E V R, Rajendran M P, Anbumani S P, 1995. A report on the incidence of anaplasmosis in sheep in Tamil Nadu. Indian Veterinary Journal. 72 (12), 1307.

Ssenyonga G S Z, Kakoma I, Montenegro-James S, Nyeko P J, Buga R, 1991. Anaplasmosis in Uganda. II. Prevalence of bovine anaplasmosis in Uganda. Annals of Tropical Medicine and Parasitology. 85 (3), 305-308.

Ssenyonga G S Z, Kakoma I, Nyeko J P, Buga R, Hansen R, 1992. Anaplasmosis in Uganda. III. Parasitological and serological evidence of Anaplasma infection in Ugandan goats. Onderstepoort Journal of Veterinary Research. 59 (2), 161-162.

Stauber E H, Autenrieth R, Markham D O, Whitbeck V, 1980. A seroepidemiologic survey of three pronghorn (Antilocapra americana) populations in southeastern Idaho, 1975-1977. Journal of Wildlife Diseases. 16 (1), 109-115.

Stiller D, Coan M E, 1995. Recent developments in elucidating tick vector relationships for anaplasmosis and equine piroplasmosis. Veterinary Parasitology. 57 (1/3), 97-108. DOI:10.1016/0304-4017(94)03114-C

Su J F, Hsu F S, 1993. Serological assays and seroprevalence of ruminant Anaplasma marginale infection in Taiwan. Journal of the Chinese Society of Veterinary Science. 19 (2), 79-89.

Surendran N S, Bhaskara Rao P, 1989. Anaplasmosis in sheep in Andhra Pradesh. Indian Veterinary Journal. 66 (7), 672.

Sweet V H, Stauber E H, 1978. Anaplasmosis: a regional serologic survey and oral antibiotic therapy in infected herds. Journal of the American Veterinary Medical Association. 172 (11), 1310-1312.

Tapia D G, Rojas M L, Bayúgar R C, Ortiz M A G, Jalil P D, Torres R A, 1996. Serological prevalence of bovine anaplasmosis in 18 districts of northern Veracruz, Mexico. (Seroprevalencia de anaplasmosis en exploraciones bovinas de 18 municipios de la zona norte de Veracruz.). Técnica Pecuaria en México. 34 (1), 38-45.

Taylor S K, Lane V M, Hunter D L, Eyre K G, Kaufman S, Frye S, Johnson M R, 1997. Serologic survey for infectious pathogens in free-ranging American bison. Journal of Wildlife Diseases. 33 (2), 308-311.

Teclaw R F, Romo S, Garcia Z, Wagner G G, 1985. A serological survey for anaplasmosis in cattle in the Mexican states of Nuevo Leon, Tamaulipas and Coahuila using the card test. Preventive Veterinary Medicine. 3 (5), 417-425. DOI:10.1016/0167-5877(85)90002-9

Tjornehoj K, Lawrence J A, Kafuwa P T, Whiteland A P, Chimera B A R, 1997. Immunisation of smallholder dairy cattle against anaplasmosis and babesiosis in Malawi. Tropical Animal Health and Production. 29 (2), 77-82. DOI:10.1007/BF02632322

Tokarnia CJ, Döbereiner J, 1962. (A importância da anaplasmose em nossos bezerros e as medidas de seu controle). In: Veterinária, 15 (3-4) 11-19.

Travassos Santos Dias J A, 1988. Veterinary parasitological survey of Timor. (Reconhecimento nosoparasitológico veterinário em Timor.). Garcia de Orta. Série de Zoologia. 15 (2), 67-88.

Uilenberg G, Rombach M C, Perie N M, Zwart D, 1980. Blood parasites of sheep in the Netherlands. II. Babesia motasi (Sporozoa, Babesiidae). Veterinary Quarterly. 2 (1), 3-14.

Vidotto M C, Vidotto O, Andrade G M, Palmer G, McElwain T, Knowles D P, 1998. Seroprevalence of Anaplasma marginale in cattle in Parana State, Brazil, by MSP-5 competitive ELISA. In: Annals of the New York Academy of Sciences [Tropical veterinary medicine: molecular epidemiology, hemoparasites and their vectors, and general topics.], 849 [ed. by Jongejan F, Goff W, Camus E]. 424-426. DOI:10.1111/j.1749-6632.1998.tb11087.x

Vidotto O, Andrade G M, Amaral C H S, Barbosa C S, Freire R L, Rocha M A, Vidotto M C, 1997. Frequency of antibodies against Babesia bigemina, B. bovis and Anaplasma marginale in dairy herds in the Londrina region, Paraná State, Brazil. (Freqüência de anticorpos contra Babesia bigemina, B. bovis e Anaplasma marginale em rebanhos leiteiros de região de Londrina, Paraná.). Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 49 (5), 655-659.

Waldrup K A, Collisson E, Bentsen S E, Winkler C K, Wagner G G, 1989. Prevalence of erythrocytic protozoa and serologic reactivity to selected pathogens in deer in Texas. Preventive Veterinary Medicine. 7 (1), 49-58. DOI:10.1016/0167-5877(89)90036-6

Yilma J M, Daniel W S, Dorchies P, 1995. Survey of ticks infesting domestic ruminants in South Wollo region of Ethiopia. Revue de Médecine Vétérinaire. 146 (3), 213-220.

Zararaz HO, Parra DG, 1977. (Estudio de la patogenicidad de dos cepas de Anaplasma marginale de Colombia). In: Revista Institituto Colombiano Agropecuario, 12 (4) 457-471.

Zaugg J L, 1985. Bovine anaplasmosis: transplacental transmission as it relates to stage of gestation. American Journal of Veterinary Research. 46 (3), 570-572.

Zaugg J L, 1990. Seasonality of natural transmission of bovine anaplasmosis under desert mountain range conditions. Journal of the American Veterinary Medical Association. 196 (7), 1106-1109.

Zaugg J L, Kuttler K L, 1985. Anaplasma marginale infections in American bison: experimental infection and serologic study. American Journal of Veterinary Research. 46 (2), 438-441.

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