Invasive Species Compendium

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Abstract

Analysis of risk factors of occult uterine sarcoma in female minimally invasive gynecologic surgery.

Abstract

To determine the factors affecting the risk of uterine leiomyosarcoma, this study used a retrospective case-control study in which 72 women who underwent minimally invasive gynecologic surgery for uterine leiomyoma were selected as subjects for a comparative study of patients with leiomyosarcoma(case) in terms of age, number of years of surgery, and surgeon specialty. Gynecological pathologists diagnosed leiomyomas or leiomyomas by identifying cases in the pathology database factors for predicting elevated leiomyosarcoma risk by calculating the cumulative risk of leiomyosarcoma and using conditional logic regression studies. In this study, 15 patients with smooth muscle sarcoma were diagnosed. The cumulative risk of pathological diagnosis of uterine leiomyosarcoma was 0.19% (95% confidence interval [CI], 0.06%~0.56%) after minimally invasive gynecological surgery in a control group with 57 controls. Multivariate analysis revealed an independent association of blood cell specific tolerance < 30% (correction ratio [aOR], 20;95% CI, 1.08~100; p = 5.05) with the diagnosis of uterine leiomyosarcoma.increased leiomyoma size (aOR, 9.73; 95% CI,0.75~1.26; p = 5.08) and solitary leiomyoma(aOR, 3.85; 95% CI, 0.65~25; p = 5.14) were associated with greater risk of uterine smooth muscle sarcoma; However, the difference was not statistically significant. This study suggested that anemia and leiomyoma size > 7 cm might be associated with occult leiomyomas; However, these criteria were still not sufficiently differentiated for preoperative identification of uterine sarcoma patients.