Invasive Species Compendium

Detailed coverage of invasive species threatening livelihoods and the environment worldwide

Abstract

Research advances and risk management of gene drives.

Abstract

Gene drives, a natural phenomenon, means a specific gene can be biased to next generation. Thisphenomenon has recently become one of the new research hotspots in field of biology. It could be used to controlpests and infectious diseases, and also to clear away invasive species and so on. It was verified in laboratory thatgene drives based on CRISPR/Cas9 system has been successfully enhanced the heritability of specific genes. Although gene drives has many potential benefits, it faces great challenges in terms of ethics and social security. Thispaper reviewed the principle of gene drives, research progress and applications in recent years, and the technicalproblems faced by this technology including risks and governance of gene drives.