A clinical trial comparing oxytetracycline, foot trimming and flunixine meglumine on time to recovery in sheep with footrot.
A randomized factorial clinical trial comparing treatments for footrot was run on 53 sheep. All received topical oxytetracycline, then sheep were given one or more of long-acting oxytetracycline, flunixine meglumine, no foot trimming, or foot trimming on day 1 or day 6 after treatment. The order of rate of recovery by 10 days was injectable antibiotic (90%), sprayed only (60%), injected and foot trimmed (50%), then foot trimmed and sprayed (25%). We hypothesise that intramuscular oxytetracycline penetrated the epidermis/dermis and killed D. nodosus allowing the foot to heal and conformation to return to normal, whilst foot trimming delayed healing.