Antibacterial properties of selected lignicolous mushrooms and fungi from Northern Serbia.
Antibacterial activity of organic extracts (70% methanol, 100% chloroform) from 10 lignicolous mushroom and fungal species - Meripilus giganteus, Laetiporus sulphureus, Coriolus versicolor, Flammulina velutipes, Ganoderma lucidum, G. applanatum, Pleurotus ostreatus, Piptoporus betulinus, Panus tigrinus, and Fistulina hepatica - was analyzed against 18 strains of bacteria using the agar-well diffusion assay. The level of antimicrobial effect was determined by dilution susceptibility tests in micro-plates. Antibiotic susceptibility assay of the bacterial strains to common antibiotics was done with the disk-diffusion method. The extracts of Piptoporus betulinus were the most active. The examined extracts, including M. giganteus and P. tigrinus, which were tested for the first time, inhibited mostly Gram-positive bacteria (Bacillus sp., Rhodococcus equi, and Staphylococcus aureus) resistant to common antibiotics. Minimal inhibitory concentrations ranged from 17.5 to 9000 µg/mL. The results demonstrate that lignicolous mushrooms and fungi may be rich sources for new biologically active products.