The acute toxicity of praziquantel to grass carp and golden shiners.
The acute toxicity and highest non-lethal concentration of praziquantel (LC0) were determined in the laboratory for grass carp (Ctenopharyngodon idella) and golden shiner (Notemigonus crysoleucas). These 2 cyprinids were known to harbour the Asian tapeworm, Bothriocephalus acheilognathi. Praziquantel was an anthelmintic used to treat fish with tapeworms. The 24- and 96-h LC50 values were 55.1 and 49.7 mg/litre for golden shiners (1.3 g) and 63.4 and 60.6 mg/litre for grass carp (9.1 g), respectively. The 24- and 96-h LC0 values were 50.0 and 45.0 mg/litre for golden shiners and 60.0 and 60.0 mg/litre for grass carp, respectively.