Experimental camelpox infection in vaccinated and unvaccinated guanacos.
The susceptibility of guanacos (Lama guanicoe) to Orthopoxvirus cameli infections and the protection afforded by a live attenuated camelpox vacccine (Ducapox) against such infections were evaluated. Two healthy adult guanacos (a male and a pregnant female) were included in the study. The female guanaco was vaccinated subcutaneously with Ducapox. 17 days after, both animals were inoculated with camelpox field strain 202/95. The female guanaco did not develop any symptoms or lesions and gave birth to a healthy cria 3 weeks after. The animal seroconverted after the vaccination. 14 days after inoculation, the male guanaco developed pox lesions over its entire body, Two small lesions were also observed in the trachea. From all lesions, Orthopoxvirus was isolated. The male guanaco seroconverted 16 days after inoculation. The animal was euthanized 21 days after infection on humane grounds.