Invasive Species Compendium

Detailed coverage of invasive species threatening livelihoods and the environment worldwide

Abstract

Anti-ulcerogenic evaluation of the methanolic extracts of some indigenous medicinal plants of Pakistan in aspirin-ulcerated rats.

Abstract

Anti-ulcerogenic activities of the methanolic extracts of 4 medicinal plants (collected from the botanical garden of PCSIR laboratories at Peshawar), against aspirin-induced gastric ulcers, were studied in rats. Their effects on the volume of gastric juice secreted, acid output, peptic activity, mucin activity and curative ratio were recorded. Bauhinia racemosa (flower buds; extract administered orally at 2 g/kg) significantly decreased the ulcer index, and Moringa pterygosperma [M. oleifera] (flower buds; 4 g/kg) showed some decrease in the ulcer index. Trianthema pentandra (whole plant; 1 g/kg) did not show any decrease in the acid or pepsin content or any increase in mucin; however, it showed a highly significant decrease in the ulcer index. Cordia latifolia (ripened fruits; 4 g/kg) did not decrease the ulcer index.