A long-range repeat cluster in chromosome 1 of the house mouse, Mus musculus, and its relation to a germline homogeneously staining region.
The C57BL genome was shown to contain about 50 copies of a long-range repeat DNA family clustered in the C-D region of chromosome 1. The repeat length was more than 50 kb, and included sequences homologous to at least 2 mRNAs. There were small differences in the copies of this repeat family, such as restriction site mutations, and gross differences like rearrangements and insertions of LINE 1 (long interspersed) elements. A germ-line, homogeneously staining region occurring as a chromosome-1 polymorphism in many feral populations of the house mouse is an amplified version of this long-range repeat cluster.