In vitro antimalarial activity of six medicinal plants.
Leaf extracts of Annona muricata, Ficus polita, Luffa aegyptiaca, Momordica charantia and Newbouldia laevis and extracts from the twigs and leaves of Moringa pterygosperma [M. oleifera] were screened for activity against Plasmodium falciparum cultured in vitro. All extracts inhibited growth in a dose-dependent manner. The IC50 values ranged from 12.6 µg/ml for N. laevis to 68.4 µg/ml for M. charantia. [For earlier work see Journal of Ethnopharmacology (1989) 25, 115-118].