Efficacy of ribosomal vaccine prepared from Pasteurella piscicida against pseudotuberculosis in cultured yellowtail.
In a comparison of seven different antigen preparations, yellowtail (Seriola quinqueradiata) were immunized twice by i.p. injection and then challenged three weeks after the last injection by immersion in a suspension of virulent Pasteurella piscicida. The antigens used were ribosomal antigens P and S (RBP and RBS), outer membrane fraction, lipopolysaccharide (LPS), precipitated antigens, extracellular products, and formalin killed cells. The RBP preparation gave the greatest protection against challenge and the highest phagocytic activity, although it provided only low specific antibody against P. piscicida LPS.