Invasive Species Compendium

Detailed coverage of invasive species threatening livelihoods and the environment worldwide

Abstract

Hepatic tumors in the guppy (Lebistes reticulatus) induced by aflatoxin B1, dimethylnitrosamine and 2-acetylaminofluorine.

Abstract

Guppies were fed 0.6 mg aflatoxin B1/100 g powdered diet for several months. This and the other carcinogens used induced hepatic damage, hyperblastic nodules, and tumours of the liver, together with damage and tumourous lesions of other organs. Carcinogenesis in a small fish provides a suitable model for simplifying carcinogenic experiments, and the possible use of these fish to screen environmental carcinogens is discussed.