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CAB Reviews

A reviews journal covering agriculture, global health, nutrition, natural resources and veterinary science

CAB Review

The application of RNA interference libraries to functional genomics studies in mammals.

Abstract

RNA interference (RNAi) technology is a gene-silencing tool with high specificity and efficiency for gene function studies. The use of RNAi libraries, which is based on this technology, promotes the significance of RNAi in gene silencing, and furthermore it provides a basis for the large-scale gene function analyses and high-throughput gene scan studies. This paper reviews the several types of RNAi library preparation, their respective construction approaches and some critical issues during RNAi library construction.

CAB Review details

  • History
  • Published: 26 May 2010
  • ISSN
  • 1749-8848
  • Publisher information
  • CABI Wallingford UK
  • Record Number
  • 20103129288