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CABI Book Info

Lyme disease: an evidence-based approach.

Book cover for Lyme disease: an evidence-based approach.

Description

This second edition provides up-to-date evidence-based research and covers the significant advances in our understanding of the disorders referred to as Lyme disease or Lyme borreliosis. Consisting of 17 chapters, this book explores the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, the role of host immunity on pathogenesis and long term prognosis. The authors provide balanced perspectives on all aspects of Lyme disease and explicitly review both the basic biology of the infection and practical clinical aspects. This new edition includes new borrelial pathogens that have been identified (B. miyamotoi, B. mayonii and B. bavariensis among others). It provides updated information on the molecular biology of the organism, neuroborreliosis, and the role of the C6 peptide in diagnosis. It also discusses the controversies about 'chronic Lyme disease', post Lyme disease syndrome, and other ongoing but non-specific symptoms that have been attributed to this infection. As the endemic footprint of Lyme disease continues to grow, this book provides a broad and detailed guide for clinicians and researchers involved with the diagnosis and treatment of the condition. Covering biology, epidemiology and therapeutics, it is also essential reading for students of global health and infectious disease.

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Book Chapters

Chapter: 1 (Page no: 1) Ticks: the vectors of Lyme disease. Author(s): Smith, R. P.
Chapter: 2 (Page no: 29) Biology of the Lyme disease agents: a selective survey of clinical and epidemiologic relevance. Author(s): Barbour, A. G.
Chapter: 3 (Page no: 45) Borreliella: interactions with the host immune system. Author(s): Sperber, K. Dattwyler, R. J.
Chapter: 4 (Page no: 58) Diagnostic testing for Lyme disease. Author(s): Auwaerter, P. G.
Chapter: 5 (Page no: 76) Global epidemiology of Borreliella burgdorferi infections. Author(s): Mead, P. S.
Chapter: 6 (Page no: 93) Antibiotic therapy for infection caused by Borrelia burgdorferi sensu lato. Author(s): Wormser, G. P.
Chapter: 7 (Page no: 105) Lyme borreliosis: the European perspective. Author(s): Strle, F. Stanek, G. Strle, K.
Chapter: 8 (Page no: 124) Lyme neuroborreliosis: a European perspective. Author(s): Dersch, R.
Chapter: 9 (Page no: 139) Medically unexplained symptoms and Lyme neuroborreliosis - not the same: a study in an endemic area of Norway. Author(s): Roaldsnes, E. Eikeland, R. Berild, D.
Chapter: 10 (Page no: 142) Erythema migrans. Author(s): Nadelman, R. B. Hu, L.
Chapter: 11 (Page no: 168) Lyme carditis. Author(s): Salik, J. R. Dudzinski, D. M.
Chapter: 12 (Page no: 180) The musculoskeletal manifestations of Lyme disease (infection with Borrelia burgdorferi). Author(s): Sigal, L. H.
Chapter: 13 (Page no: 202) Nervous system involvement. Author(s): Halperin, J. J.
Chapter: 14 (Page no: 216) Lyme disease in children. Author(s): Shapiro, E. D.
Chapter: 15 (Page no: 227) The psychology of 'post-Lyme disease syndrome' and 'not Lyme'. Author(s): Hassett, A. L. Sigal, L. H.
Chapter: 16 (Page no: 247) Chronic Lyme disease. Author(s): Marques, A.
Chapter: 17 (Page no: 262) Lyme disease: the great controversy. Author(s): Halperin, J. J. Baker, P. Wormser, G. P.