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CABI Book Chapter

Tuberculosis, leprosy and mycobacterial diseases of man and animals: the many hosts of mycobacteria.

Book cover for Tuberculosis, leprosy and mycobacterial diseases of man and animals: the many hosts of mycobacteria.


Mycobacteria have been associated with human and animal disease for millennia. This book is founded on a principle of cross-disciplinary inclusion and the belief that by bringing together all members of the mycobacterial research community we could achieve a better understanding of mycobacteria and the diseases caused by them, and thus contribute to knowledge and the development of products to imp...


Chapter 2 (Page no: 17)

Comparative mycobacteriology of the Mycobacterium tuberculosis complex.

This chapter discusses current knowledge on the microbiology of Mycobacterium tuberculosis complex (MTBC), focusing mainly on comparisons between M, tuberculosis and M. bovis as examples of human- and animal-adapted strains, respectively. Evolutionary mechanisms of the MTBC to their specific hosts, as well as the emergence of host adaptation to these pathogens, are described.

Other chapters from this book

Chapter: 1 (Page no: 1) Introduction and epidemiology of Mycobacterium tuberculosis complex in humans. Author(s): Shamputa, I. C. Cho SangNae Lebron, J. Via, L. E.
Chapter: 3 (Page no: 30) Immunopathogenesis of tuberculosis in humans. Author(s): Rengarajan, J. Sia, J. K. Day, C. L.
Chapter: 4 (Page no: 72) Current methods for diagnosis of human tuberculosis and considerations for global surveillance. Author(s): Sakamuri, R. M. Moodley, P. Yusim, K. Feng, S. H. Sturm, A. W. Korber, B. T. M. Mukundan, H.
Chapter: 5 (Page no: 103) Development of next-generation TB vaccines: comparative approaches in humans and animals. Author(s): Brennan, M. J. Samad, S. Hewinson, R. G.
Chapter: 6 (Page no: 112) The continuing co-evolution of Mycobacterium tuberculosis and Homo sapiens. Author(s): Barry, C. E., III
Chapter: 7 (Page no: 124) The global distribution of Mycobacterium bovis. Author(s): Smith, N. H.
Chapter: 8 (Page no: 136) Immunopathogenesis of Mycobacterium bovis infection of cattle. Author(s): Waters, W. R. Hope, J. C. Hamilton, C. A. Palmer, M. V. McNair, J. Skuce, R. A. Allen, A. R. Buddle, B. M. Villarreal-Ramos, B. Vordermeier, H. M.
Chapter: 9 (Page no: 168) Diagnosis of Mycobacterium bovis infection in cattle. Author(s): Buddle, B. M. Lisle, G. W. de Waters, W. R. Vordermeier, H. M.
Chapter: 10 (Page no: 185) Vaccination of cattle against tuberculosis. Author(s): Vordermeier, H. M. Buddle, B. M. Villarreal-Ramos, B. Jones, G. J. Hewinson, R. G. Waters, W. R.
Chapter: 11 (Page no: 202) Mycobacterium bovis/M. caprae infection in goats and sheep: introduction, epidemiology and control measures. Author(s): Aranaz, A.
Chapter: 12 (Page no: 216) Mycobacterial infections in camelids. Author(s): Rhodes, S. Crawshaw, T. Rua-Domenech, R. de la Bradford, S. Lyashchenko, K. P. Mamo, G. Summers, D. Wernery, U. Zanolari, P.
Chapter: 13 (Page no: 235) Tuberculosis in companion animal species. Author(s): Gunn-Moore, D. A. Lalor, S.
Chapter: 14 (Page no: 259) Mycobacterial infections in elephants. Author(s): Mikota, S. K. Lyashchenko, K. P. Lowenstine, L. Agnew, D. Maslow, J. N.
Chapter: 15 (Page no: 277) Mycobacterial infections in other zoo animals. Author(s): Miller, M. A. Lyashchenko, K. P.
Chapter: 16 (Page no: 296) Tuberculosis in badgers (Meles meles). Author(s): Chambers, M. A. Gormley, E. Corner, L. A. L. Smith, G. C. Delahay, R. J.
Chapter: 17 (Page no: 313) Tuberculosis in pigs and wild boar. Author(s): Gortázar, C. Vicente, J. Fuente, J. de la Nugent, G. Nol, P.
Chapter: 18 (Page no: 325) Australian brushtail possum: a highly susceptible host for Mycobacterium bovis. Author(s): Buddle, B. M. Lisle, G. W. de Corner, L. A. L.
Chapter: 19 (Page no: 334) Tuberculosis in wild and captive deer. Author(s): Palmer, M. V. O'Brien, D. J. Griffin, J. F. Nugent, G. Lisle, G. W. de Ward, A. Delahay, R. J.
Chapter: 20 (Page no: 365) Tuberculosis in South African wildlife: lions, African buffalo and other species. Author(s): Michel, A. L. Klerk-Lorist, L. M. de Buss, P. Hofmeyr, M. Cooper, D. Bengis, R. G.
Chapter: 21 (Page no: 386) Novel Mycobacterium tuberculosis complex spp. in group-living African mammals. Author(s): Alexander, K. A. Sanderson, C. E. Laver, P. N.
Chapter: 22 (Page no: 402) Rabbit model of mycobacterial diseases. Author(s): Subbian, S. Karakousis, P. C. Kaplan, G.
Chapter: 23 (Page no: 419) Laboratory models of tuberculosis: guinea pigs. Author(s): Podell, B. K. Williams, A. Izzo, A. Basaraba, R.
Chapter: 24 (Page no: 433) Of mice and mycobacteria: lessons from a manipulatable model. Author(s): Cooper, A. M. Pearl, J. E.
Chapter: 25 (Page no: 451) Non-human primate laboratory models of tuberculosis. Author(s): Sharpe, S. Via, L. E. Verreck, F. A. W. Lin, P. L.
Chapter: 26 (Page no: 470) Mycobacterium leprae in humans. Author(s): Spencer, J. S. Wheat, W. H. Brennan, P. J. Barreto, J. G. Salgado, C. G.
Chapter: 27 (Page no: 491) Animal models for leprosy research. Author(s): Adams, L. B. Pena, M. T. Sharma, R. Lahiri, R. Truman, R. W.
Chapter: 28 (Page no: 512) Mycobacterium avium subsp. paratuberculosis infection, immunology and pathology of livestock. Author(s): Stabel, J. R. Bannantine, J. P. Hostetter, J.
Chapter: 29 (Page no: 538) Nontuberculous mycobacterial infections. Author(s): Falkinham, J. O., III

Chapter details

  • Author Affiliation
  • Veterinary Sciences Centre, School of Veterinary Medicine, University College Dublin (UCD), Belfield, Dublin, Irish Republic.
  • Year of Publication
  • 2015
  • ISBN
  • 9781780643960
  • Record Number
  • 20153322761