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CAB eBooks

Ebooks on agriculture and the applied life sciences from CAB International

CABI Book Chapter

Horse genetics.

Book cover for Horse genetics.

Description

The second edition of this book contains chapters on horse breeding and genetics, including the evolution and domestication of horses; genomics; the genetics of coat colour and pattern, diseases and performance; karyotypes and chromosome abnormalities; breeding programmes; epigenetics; genetic variation within and between breeds; the taxonomy of Equidae; questions and answers regarding the genetic...

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Chapter 6 (Page no: 53)

Tobiano, white, sabino, and roan (KIT).

KIT mutations play a key role in producing white spotting patterns in horses. However, not all white spotting patterns in horses are products of the KIT locus. The next few chapters describe the genetics of the traits gray, overo, splashed white and leopard, all of which are encoded by genes elsewhere in the genome. Nevertheless, the diversity of mutations and phenotypes that occur associated with KIT are remarkable. The association of KIT with white spotting is not confined to horses, of course, and we draw on a remarkable body of knowledge about the genetics of KIT and melanogenesis in other species, and especially from studies in mice (Geissler et al., 1988; Besmer et al., 1993; Johansson Moller et al., 1996). As noted above, we still have not identified the mutations responsible for sabino in draft horses, nor the mutations for roan patterns. The work of Marklund et al. (1999) indicated that at least one of the RN mutations is associated with KIT, but it remains possible that mutations in other genes can create the roan phenotype - or the sabino phenotype of draft horses.

Other chapters from this book

Chapter: 1 (Page no: 1) Evolution and domestication of horses. Author(s): Bailey, E. Brooks, S. A.
Chapter: 2 (Page no: 6) Basic horse genetics. Author(s): Bailey, E. Brooks, S. A.
Chapter: 3 (Page no: 27) Horse genomics. Author(s): Bailey, E. Brooks, S. A.
Chapter: 4 (Page no: 36) Black, bay, and chestnut (extension and agouti). Author(s): Bailey, E. Brooks, S. A.
Chapter: 5 (Page no: 42) Color diluting genes. Author(s): Bailey, E. Brooks, S. A.
Chapter: 7 (Page no: 65) Gray. Author(s): Bailey, E. Brooks, S. A.
Chapter: 8 (Page no: 69) Frame overo and splashed white. Author(s): Bailey, E. Brooks, S. A.
Chapter: 9 (Page no: 77) Leopard (Appaloosa) spotting. Author(s): Bailey, E. Brooks, S. A.
Chapter: 10 (Page no: 81) Putting it all together: color by design. Author(s): Bailey, E. Brooks, S. A.
Chapter: 11 (Page no: 86) Parentage testing. Author(s): Bailey, E. Brooks, S. A.
Chapter: 12 (Page no: 95) Medical genetics. Author(s): Bailey, E. Brooks, S. A.
Chapter: 13 (Page no: 112) The horse karyotype and chromosomal abnormalities. Author(s): Bailey, E. Brooks, S. A.
Chapter: 14 (Page no: 123) Genetics of performance. Author(s): Bailey, E. Brooks, S. A.
Chapter: 15 (Page no: 135) Pedigrees and breeding schemes. Author(s): Bailey, E. Brooks, S. A.
Chapter: 16 (Page no: 146) Y chromosomes, mitochondria, epigenetics, and incomplete penetrance. Author(s): Bailey, E. Brooks, S. A.
Chapter: 17 (Page no: 156) Genetic nature of breeds. Author(s): Bailey, E. Brooks, S. A.
Chapter: 18 (Page no: 166) Equus. Author(s): Bailey, E. Brooks, S. A.
Chapter: 19 (Page no: 175) Frequently asked questions. Author(s): Bailey, E. Brooks, S. A.
Chapter: 20 (Page no: 186) Where do we go from here? Author(s): Bailey, E. Brooks, S. A.