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CAB eBooks

Ebooks on agriculture and the applied life sciences from CAB International

CABI Book Chapter

Parasitic nematodes: molecular biology, biochemistry and immunology.

Book cover for Parasitic nematodes: molecular biology, biochemistry and immunology.


Inclusive of 20 chapters subdivided into 4 parts, this book's second edition covers latest updates in the current understanding of the molecular biology, biochemistry and immunology of parasitic nematodes of humans, domestic animals and plants. Specific topics discussed in each chapter include horizontal gene transfer, immune expulsion mechanisms, genetics of human susceptibility to nematode infec...


Chapter 16 (Page no: 308)

The Wolbachia bacterial endosymbionts of filarial nematodes.

This chapter discusses the symbiotic relationship between Wolbachia and filarial nematodes as indicated by antibiotic treatments and the combined analyses of the completed genomes of Wolbachia and its Brugia malayi host. Potential mechanisms that explain how Wolbachia activate innate and adaptive inflammatory responses associated with driving disease pathogenesis are described, as well as relevant molecular ligands and immunological pathways leading to disease pathogenesis.

Other chapters from this book

Chapter: 1 (Page no: 1) The genome of Pristionchus pacificus and the evolution of parasitism. Author(s): Sommer, R. J. Ogawa, A.
Chapter: 2 (Page no: 15) Life-history plasticity and responses to host defence. Author(s): Viney, M. E.
Chapter: 3 (Page no: 30) The complex armoury of plant-parasitic nematodes. Author(s): Bird, D. M. DiGennaro, P. M.
Chapter: 4 (Page no: 42) Innate immunity in Caenorhabditis elegans and other nematodes. Author(s): Rosso, M. N. Pujol, N. Ewbank, J. J.
Chapter: 5 (Page no: 67) Nematodes and regulatory T cells. Author(s): Smith, K. A. Maizels, R. M.
Chapter: 6 (Page no: 84) The alternatively activated macrophage. Author(s): Rückerl, D. Jenkins, S. Allen, J. E.
Chapter: 7 (Page no: 106) Regulation of immunity and inflammation following intestinal helminth infection. Author(s): Hepworth, M. R. Grencis, R. K. Artis, D.
Chapter: 8 (Page no: 130) Influence of nematodes on Mycobacterium tuberculosis and related mycobacteriae: from disease outcome to immune responses. Author(s): Subash Babu Nutman, T. B.
Chapter: 9 (Page no: 144) Modulation of autoimmune and allergic responses by defined nematode molecules. Author(s): Harnett, W. Al-Riyami, L. Rzepecka, J. Harnett, M. M.
Chapter: 10 (Page no: 156) Genetics and mechanisms of drug resistance in nematodes. Author(s): Prichard, R. Lespine, A.
Chapter: 11 (Page no: 184) Genetics of resistance to hookworm infection. Author(s): Quinnell, R. J. Behnke, J. M.
Chapter: 12 (Page no: 209) Vaccination against filarial nematodes. Author(s): Lustigman, S. Klei, T. R.
Chapter: 13 (Page no: 245) A vaccine against Haemonchus contortus: current status and future possibilities. Author(s): Knox, D.
Chapter: 14 (Page no: 261) Nematodes and human therapeutic trials. Author(s): Elliott, D. E. Pritchard, D. Brown, A. Weinstock, J. V.
Chapter: 15 (Page no: 279) Nematode neuropeptide communication systems. Author(s): Mousley, A. McVeigh, P. Dalzell, J. J. Maule, A. G.
Chapter: 17 (Page no: 337) The nematode cuticle: synthesis, modification and turnover. Author(s): Page, A. P.
Chapter: 18 (Page no: 351) Proteases of nematodes: from free-living to parasite. Author(s): Britton, C.
Chapter: 19 (Page no: 375) Nematode allergens. Author(s): Steinfelder, S. Rausch, S. Lucius, R. Hartmann, S.
Chapter: 20 (Page no: 397) The unusual lipid-binding proteins of nematodes: NPAs, nemFABPs and FARs. Author(s): Kennedy, M. W. Córsico, B. Cooper, A. Smith, B. O.