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CABI Book Chapter

Tuberculosis: laboratory diagnosis and treatment strategies.

Book cover for Tuberculosis: laboratory diagnosis and treatment strategies.

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Chapter 3 (Page no: 34)

Improving on the LJ slope - automated liquid culture.

This chapter describes the different types of media for culture and isolation of mycobacteria, and discusses the adaptation of automated liquid culture systems for the qualitative and quantitative drug susceptibility testing of Mycobacterium tuberculosis and non-tuberculous mycobacteria.

Other chapters from this book

Chapter: 1 (Page no: 3) Improving on sputum smear microscopy for diagnosis of tuberculosis in resource-poor settings. Author(s): Ramsay, A. Steingart, K. R. Madhukar Pai
Chapter: 2 (Page no: 13) Molecular diagnosis of active pulmonary tuberculosis. Author(s): Bateson, A. L. Reddington, K. O'Grady, J.
Chapter: 4 (Page no: 46) Interferon-gamma release assays in the diagnosis of latent tuberculosis infection. Author(s): Ajit Lalvani Manish Pareek
Chapter: 5 (Page no: 67) Measuring tuberculosis immune responses in the lung - the correct target? Author(s): Breen, R. Lipman, M.
Chapter: 6 (Page no: 81) Sniffing out tuberculosis. Author(s): McNerney, R. Turner, C.
Chapter: 7 (Page no: 95) Role of phenotypic methods for drug susceptibility testing of M. tuberculosis isolates in the era of MDR and XDR epidemics. Author(s): Heifets, L.
Chapter: 8 (Page no: 108) Genotypic measures of antibiotic susceptibility. Author(s): Mathys, V. Mathema, B. Bifani, P.
Chapter: 9 (Page no: 125) Molecular tools for fast identification of resistance and characterization of MDR/XDR-TB. Author(s): Cadmus, S. Soolingen, D. van
Chapter: 10 (Page no: 139) Monitoring therapy by bacterial load. Author(s): O'Sullivan, D. M.
Chapter: 11 (Page no: 147) Modelling responses to tuberculosis treatment. Author(s): Davies, G. R.
Chapter: 12 (Page no: 164) Measuring gene expression by quantitative PCR (qPCR). Author(s): Honeyborne, I.
Chapter: 13 (Page no: 173) Transcriptomic approaches to mapping responses to drug therapy for tuberculosis. Author(s): Waddell, S. J. Butcher, P. D.
Chapter: 14 (Page no: 184) Mycobacterial lipid bodies and resuscitation-promoting factor dependency as potential biomarkers of response to chemotherapy. Author(s): Garton, N. J. Mukamolova, G. V. Barer, M. R.
Chapter: 15 (Page no: 197) Clinical trials in tuberculosis chemotherapy: the challenges. Author(s): Gillespie, S. H.
Chapter: 16 (Page no: 206) The identification of 2-aminothiazole-4-carboxylates (ATCs) as a new class of tuberculosis agent: a lesson in 'HIT' identification. Author(s): Coxon, G.
Chapter: 17 (Page no: 219) Rifamycins revisited. Author(s): Boeree, M. J.
Chapter: 18 (Page no: 232) Therapy of the XDR-TB patient with thioridazine - an old drug with new applications. Author(s): Amaral, L. Martins, M. Couto, I. Viveiros, M.
Chapter: 19 (Page no: 243) Vaccines for tuberculosis. Author(s): McShane, H.

Chapter details

  • Author Affiliation
  • Unit of Mycobacteriology, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa (IHMT/UNL), Rua da Junqueira, 100, 1349-008 Lisbon, Portugal.
  • Year of Publication
  • 2013
  • ISBN
  • 9781845938079
  • Record Number
  • 20133149035