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Improving lives by solving problems in agriculture and the environment

Antimicrobial Stewardship

Antimicrobial Stewardship

Principles and Practice

December 2016 / Hardback / 450 Pages / 9781780644394 £150.00 / €195.00 / $250.00
With 10% online discount: £135.00 / €175.50 / $225.00
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Main Description

In an age where antimicrobial resistance amongst pathogens grows more prevalent, particularly in the hospital setting, antimicrobial stewardship is an evidence-based, proven measure in the battle against resistance and infection.

This single comprehensive, definitive reference work is written by an international team of acknowledged experts in the field. The authors explore the effective use of coordinated antimicrobial interventions to change prescribing practice and help slow the emergence of antimicrobial resistance, ensuring that antimicrobials remain an effective treatment for infection.

Amongst the first of its kind, this book provides infectious disease physicians, administrators, laboratory, pharmacy, nursing and medical staff with practical guidance in setting up antimicrobial stewardship programs in their institutions with the aim of selecting the optimal antimicrobial drug regimen, dose, duration of therapy, and route of administration.


Suitable for researchers and practitioners of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology and infectious diseases.

    • Part I: Overview of Antibiotic Stewardship
  • Ch.1: Principles of Antimicrobial Stewardship
  • Ch 2: Clinical Perspective of Antimicrobial Stewardship
  • Ch 3: History of Antimicrobial Stewardship
  • Ch 4: The Importance of Education in Antimicrobial Stewardship
    • Part II: Antibiotic Resistance Principles in Antibiotic Stewardship
  • Ch 5: Intrinsic and Acquired Mechanisms of Resistance
  • Ch 6: Antimicrobial Resistance: Selection vs. Induction
  • Ch 7: Colonization and its importance for emergence of clinical resistance
  • Ch 8: Antibiotic Resistance: associations and implications for antibiotic usage strategies to control multi-resistant bacteria
    • Part III: Microbiology Laboratory Role in Antibiotic Stewardship
  • Ch 9: The role of active surveillance in the prevention of healthcare-acquired infections and antibiotic stewardship
  • Ch 10: Role of Antibiogram in Antibiotic Stewardship
  • Ch 11: Selective Reporting and Antimicrobial Stewardship
  • Ch 12: Role of New Diagnostics to Enhance Antibiotic Stewardship Efforts
    • Part IV: Infection Control Aspects of Antibiotic Stewardship
  • Ch 13: Epidemiology of S aureus and enterococci in children and an overview of antimicrobial resistance
  • Ch 14: Epidemiology of multi-drug resistant gram-negative organisms
  • Ch 15: Pathogenesis and Epidemiology of Clostridium difficile Infection: Implications for Antibiotic Stewardship
  • Ch 16: Role of the Hospital Epidemiologist in Supporting Antimicrobial Stewardship
    • Part V: Pharmacokinetic (PK) & Pharmacodynamic (PD) Aspects of Antibiotic Dosing in Antibiotic Stewardship
  • Ch 17: Principles of Pharmacokinetic / Pharmacodynamic Optimization for Antibiotic Dosing
  • Ch 18: Optimal use of Gram-negative antibiotics in the real world: providing effective therapy while minimizing resistance
  • Ch19: Optimal Use of Fluoroquinolones
  • Ch 20: Optimal Use of Beta-lactam Antibiotics
  • Ch 21: Current Approach to Optimal Use and Dosing of Vancomycin in Adult Patients
  • Ch 22: Principles of IV to PO Switch
    • Part VI: Pharmacy Department Role in Antibiotic Stewardship
  • Ch 23: Role of Pharmacists in Antimicrobial Stewardship
  • Ch 24: Formulary Management and Economic Considerations; Bridging the Gap between Quality Care and Cost
  • Ch 25: Approaches in benchmarking
  • Ch 26: Development and execution of stewardship interventions
  • Ch 27: Technologic support for antimicrobial stewardship
    • Part VII: Measuring Outcomes in Antibiotic Stewardship Programs
  • Ch 28: Role of Guidelines and Statistical Milestones for Antimicrobial Stewardship
  • Ch 29: Economic considerations of Antimicrobial Stewardship Programs
  • Ch 30: Pharmacoeconomic Implications of Antimicrobial Adverse Events
  • Ch 31: Antimicrobial stewardship programs in areas of increased pathogen resistance
    • Part VIII: Antimicrobial Stewardship and Various Practice Sites
  • Ch 32: Role of Antimicrobial Stewardship in Pediatrics
  • Ch 33: Antimicrobial Stewardship in the Intensive Care Unit
  • Ch 34: Role of Antimicrobial Stewardship in a Community Hospital
  • Ch 35: Outpatient Parenteral Antimicrobial Therapy (OPAT)
  • Ch 36: The Importance of Interdisciplinary Collaboration in Antimicrobial Stewardship: Immersion of Future Healthcare Professionals
  • Ch 37: Antimicrobial Stewardship and the Importance of Working with the Government and Pharmaceutical Industry
  • Ch 38: Hospitalist Perspective on the Role of Antimicrobial Stewardship

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