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Abstract

There is increasing evidence that dosage compensation is not a ubiquitous feature following sex chromosome evolution, especially not in organisms where females are the heterogametic sex, like in birds. Even when it occurs, compensation can be incomplete and limited to dosage-sensitive genes....

Author(s)
Uebbing, S.; Konzer, A.; Xu LuoHao; Backström, N.; Brunström, B.; Bergquist, J.; Ellegren, H.
Publisher
Oxford University Press, Oxford, UK
Citation
Molecular Biology and Evolution, 2015, 32, 10, pp 2716-2725
Abstract

Insight into the molecular evolution of birds has been offered by the steady accumulation of avian DNA sequence data, recently culminating in the first draft sequence of an avian genome, that of chicken. By studying avian molecular evolution we can learn about adaptations and phenotypic evolution...

Author(s)
Ellegren, H.
Publisher
S Karger AG, Basel, Switzerland
Citation
Cytogenetic and Genome Research, 2007, 117, 1/4, pp 120-130
Abstract

Resolving the phylogenetic relationships among birds is a classical problem in systematics, and this is particularly so when it comes to understanding the relationships among Neoaves. Previous phylogenetic inference of birds has been limited to mitochondrial genomes or a few nuclear genes. Here, we ...

Author(s)
Nabholz, B.; Künstner, A.; Wang, R.; Jarvis, E. D.; Ellegren, H.
Publisher
Oxford University Press, Oxford, UK
Citation
Molecular Biology and Evolution, 2011, 28, 8, pp 2197-2210
Abstract

It has been speculated that the sex chromosomes of mammals and birds share a common chromosomal ancestry. It was shown that the 2 genes, ATP5A1 and CHD1, so far assigned to the female-specific W chromosome of birds, both had very closely related copies on the Z chromosome but were not...

Author(s)
Fridolfsson, A. K.; Cheng, H.; Copeland, N. G.; Jenkins, N. A.; Liu HsiaoChing; Raudsepp, T.; Woodage, T.; Chowdhary, B.; Halverson, J.; Ellegren, H.
Citation
Proceedings of the National Academy of Sciences of the United States of America, 1998, 95, 14, pp 8147-8152
Abstract

The powerful pressures of sexual and natural selection associated with species recognition and reproduction are thought to manifest in a faster rate of evolution in sex-biased genes, an effect that has been documented particularly for male-biased genes expressed in the reproductive tract. However,...

Author(s)
Mank, J. E.; Hultin-Rosenberg, L.; Axelsson, E.; Ellegren, H.
Publisher
Society for Molecular Biology and Evolution, Lawrence, USA
Citation
Molecular Biology and Evolution, 2007, 24, 12, pp 2698-2706
Abstract

Our knowledge of avian genomics has increased rapidly over the past few years, culminating in the recent publication of a draft sequence of the chicken genome, a milestone event in avian genetics and evolutionary biology. Comparative analysis reveals a compact avian genome structure containing a...

Author(s)
Ellegren, H.
Publisher
Elsevier Science Ltd, London, UK
Citation
Trends in Ecology & Evolution, 2005, 20, 4, pp 180-186
Abstract

A distinctive feature of the avian genome is the large heterogeneity in the size of chromosomes, which are usually classified into a small number of macrochromosomes and numerous microchromosomes. These chromosome classes show characteristic differences in a number of interrelated features that...

Author(s)
Axelsson, E.; Webster, M. T.; Smith, N. G. C.; Burt, D. W.; Ellegren, H.
Publisher
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, USA
Citation
Genome Research, 2005, 15, 1, pp 120-125
Abstract

The human X chromosome exhibits four "evolutionary strata," interpreted to represent distinct steps in the process whereby recombination became arrested between the proto X and proto Y. To test if this is a general feature of sex chromosome evolution, we studied the Z-W sex chromosomes of birds,...

Author(s)
Handley, L. J. L.; Ceplitis, H.; Ellegren, H.
Publisher
Genetics Society of America, Bethesda, USA
Citation
Genetics, 2004, 167, 1, pp 367-376
Abstract

The vast majority of the mammalian genome does not code for proteins, and a fundamental question in genomics is: What proportion of the noncoding mammalian genome is functional? Most attempts to address this issue use sequence comparisons between highly diverged mammals such as human and mouse to...

Author(s)
Smith, N. G. C.; Brandström, M.; Ellegren, H.
Publisher
Elsevier, New York, USA
Citation
Genomics (San Diego), 2004, 84, 5, pp 806-813
Abstract

Birds are characterized by female heterogamety; females carry the Z and W sex chromosomes, while males have two copies of the Z chromosome. We suggest here that full differentiation of the Z and W sex chromosomes of birds did not take place until after the split of major contemporary lineages, in...

Author(s)
Ellegren, H.; Carmichael, A.
Publisher
Genetics Society of America, Bethesda, USA
Citation
Genetics, 2001, 158, 1, pp 325-331

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