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Abstract

SOX proteins constitute a large family of diverse, well-conserved transcription factors present in vertebrates and invertebrates, and also implicated in control of many developmental processes. Our objectives have been to identify Sox14 gene of goat (Capra hircus), cow (Bos taurus) and rat (Rattus...

Author(s)
Popovic, J.; Stevanovic, M.
Publisher
Indian Academy of Sciences, Bangalore, India
Citation
Journal of Genetics, 2009, 88, 1, pp 15-24
Abstract

Motivation: Evolutionary conservation of DNA sequences provides a tool for the identification of functional elements in genomes. We have created a database of evolutionary conserved regions (ECRs) in vertebrate genomes, entitled ECRbase, which is constructed from a collection of whole-genome...

Author(s)
Loots, G.; Ovcharenko, I.
Publisher
Oxford University Press, Oxford, UK
Citation
Bioinformatics, 2007, 23, 1, pp 122-124
Abstract

Background: A number of vertebrate highly conserved elements (HCEs) have been detected and their genomic interval distances have been reported to be more conserved than protein coding genes among mammalian genomes. A characteristic of the human - non-mammalian comparisons is a bimodal distribution...

Author(s)
Sun Hong; Skogerbø, G.; Zheng XiaoHui; Liu Wei; Li YiXue
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2009, 10, 133, pp (27 March 2009)
Abstract

Dogs and rats have a highly developed capability to detect and identify odorant molecules even at minute concentrations. Previous analyses have shown that the olfactory receptors (ORs) that specifically bind odorant molecules are encoded by the largest gene family sequenced in mammals so far. Five...

Author(s)
Quignon, P.; Giraud, M.; Rimbault, M.; Lavigne, P.; Tacher, S.; Morin, E.; Retout, E.; Valin, A. S.; Lindblad-Toh, K.; Nicolas, J.; Galibert, F.
Publisher
BioMed Central Ltd, London, UK
Citation
Genome Biology, 2005, 6, 10, pp R83
Abstract

We describe a whole-genome comparative analysis of the human, mouse, and rat genomes to describe the average substitution patterns of four genomic regions: ancient repeats, rodent-specific DNA, exons, and conserved (coding and noncoding) regions, and to identify rodent evolutionary hotspots. In all ...

Author(s)
Yap, V. B.; Pachter, L.
Publisher
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, USA
Citation
Genome Research, 2004, 14, 4, pp 574-579
Abstract

Completion of the Rattus norvegicus genome sequence enabled a global inventory and analysis of the nuclear receptors (NRs) in three mammalian species. Forty-nine NR members were found in mouse, 48 in human. Forty-seven were found in the rat, with gaps at the locations expected for the other two....

Author(s)
Zhang, Z. D.; Burch, P. E.; Cooney, A. J.; Lanz, R. B.; Pereira, F. A.; Wu, J. Q.; Gibbs, R. A.; Weinstock, G.; Wheeler, D. A.
Publisher
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, USA
Citation
Genome Research, 2004, 14, 4, pp 580-590
Abstract

We have determined the sequence of a 4-Mb interval on rat chromosome 20p12 that encompasses the rat major histocompatibility complex (MHC). This is the first report of a finished sequence for a segment of the rat genome and constitutes one of the largest contiguous sequences thus far for rodent...

Author(s)
Hurt, P.; Walter, L.; Sudbrak, R.; Klages, S.; Müller, I.; Shiina, T.; Inoko, H.; Lehrach, H.; Günther, E.; Reinhardt, R.; Himmelbauer, H.
Publisher
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, USA
Citation
Genome Research, 2004, 14, 4, pp 631-639
Abstract

Rattus norvegicus is an important experimental organism and interesting to evolutionary biologists. The recently published d raft rat genome sequence provides us with insights into both the rat's evolution and its physiology. We learn more about genome evolution and, in particular, the adaptive...

Author(s)
Hancock, J. M.
Publisher
John Wiley and Sons, Inc, New York, USA
Citation
BioEssays, 2004, 26, 10, pp 1039-1042
Abstract

The availability of the rat genome sequence, and detailed three-way comparison of the rat, mouse and human genomes, is revealing a great deal about mammalian genome evolution. Together with recent developments in cloning technologies, this heralds an important phase in rat research.

Author(s)
Mullins, L. J.; Mullins, J. J.
Publisher
BioMed Central Ltd, London, UK
Citation
Genome Biology, 2004, 5, 5, pp 221-221.3
Abstract

We conducted a comprehensive search for conserved elements in vertebrate genomes, using genome-wide multiple alignments of five vertebrate species (human, mouse, rat, chicken, and Fugu rubripes). Parallel searches were performed with multiple alignments of four insect species (three species of ...

Author(s)
Siepel, A.; Bejerano, G.; Pedersen, J. S.; Hinrichs, A. S.; Hou, M. M.; Rosenbloom, K.; Clawson, H.; Spieth, J.; Hillier, L. W.; Richards, S.; Weinstock, G. M.; Wilson, R. K.; Gibbs, R. A.; Kent, W. J.; Miller, W.; Haussler, D.
Publisher
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, USA
Citation
Genome Research, 2005, 15, 8, pp 1034-1050

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