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Abstract

Mx proteins are antiviral GTPases, which are induced by type I IFN and virus infection. Analysis of the Atlantic salmon genome revealed the presence of 9 Mx genes localized to three chromosomes. A cluster of three Mx genes (SsaMx1-SsaMx3), which includes previously cloned Mx genes, is present on...

Author(s)
Robertsen, B.; Greiner-Tollersrud, L.; Jørgensen, L. G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Developmental and Comparative Immunology, 2019, 90, pp 80-89
Abstract

IFN-kappa (IFN-κ) is a type I IFN expressed by keratinocytes, monocytes and dendritic cells with important roles during the innate immune response period. This research was conducted to elaborate the evolution and characteristics of IFN-κ in poultry. Chicken IFN-κ is located on the sex-determining...

Author(s)
Gao MingChun; Guo YongLi; Du JiWen; Song ZhiFeng; Luo XiuXin; Wang JunWei; Han WenYu
Publisher
Elsevier Ltd, Oxford, UK
Citation
Developmental and Comparative Immunology, 2018, 89, pp 44-53
Abstract

Interferons (IFNs) are essential components of the host innate immune system and define first-line of defence against pathogens. In mammals, several type I IFNs are identified, however, only limited data is available on the repertoire of IFNs in avian species. Here we report the characterization of ...

Author(s)
Santhakumar, D.; Iqbal, M.; Nair, V.; Munir, M.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2017, 7, 6, pp 2719
Abstract

Background: The interferon-induced transmembrane (IFITM) protein family comprises a class of restriction factors widely characterised in humans for their potent antiviral activity. Their biological activity is well documented in several animal species, but their genetic variation and biological...

Author(s)
Bassano, I.; Ong SweeHoe; Sanz-Hernandez, M.; Vinkler, M.; Kebede, A.; Hanotte, O.; Onuigbo, E.; Fife, M.; Kellam, P.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2019, 20, 272, pp (5 April 2019)
Abstract

Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription factors in the Janus kinase (JAK)/STAT signaling pathway, and it was previously considered as acute phase response factor. A number of interleukins (ILs) such as IL-5, IL-6, IL-9, IL-10, IL-12, and IL-22...

Author(s)
Bathige, S. D. N. K.; Thulasitha, W. S.; Umasuthan, N.; Jayasinghe, J. D. H. E.; Wan Qiang; Nam BoHye; Lee JeHee
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2017, 186, pp 29-40
Abstract

Brevibacillus laterosporus is a spore-forming bacterium that causes a secondary infection in beehives following European Foulbrood disease. To better understand the contributions of Brevibacillus bacteriophages to the evolution of their hosts, five novel phages (Jenst, Osiris, Powder, SecTim467,...

Author(s)
Berg, J. A.; Merrill, B. D.; Crockett, J. T.; Esplin, K. P.; Evans, M. R.; Heaton, K. E.; Hilton, J. A.; Hyde, J. R.; McBride, M. S.; Schouten, J. T.; Simister, A. R.; Thurgood, T. L.; Ward, A. T.; Breakwell, D. P.; Hope, S.; Grose, J. H.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2016, 11, 6, pp e0156838
Abstract

The complement components C1r and C1s play a crucial role in innate immunity via activation of the classical complement cascade system. As initiators of the pathogen-induced signaling cascade, C1r and C1s modulate innate immunity. In order to understand the immune responses of teleost C1r and C1s, ...

Author(s)
Godahewa, G. I.; Bathige, S. D. N. K.; Herath, H. M. L. P. B.; Noh JaeKoo; Lee JeHee
Publisher
Elsevier Ltd, Oxford, UK
Citation
Fish & Shellfish Immunology, 2015, 46, 2, pp 656-668
Abstract

Duck is susceptible to many pathogens, such as duck hepatitis virus, duck enteritis virus (DEV), duck tembusu virus, H5N1 highly pathogenic avian influenza virus (HPAIV) in particular. With the significant role of duck in the evolution of H5N1 HPAIV, control and eradication of H5N1 HPAIV in duck...

Author(s)
Zou Zhong; Hu Yong; Liu ZhiGang; Zhong Wei; Cao HangZhou; Chen HuanChun; Jin MeiLin
Publisher
BioMed Central Ltd, London, UK
Citation
Veterinary Research, 2015, 46, 42, pp (16 April 2015)
Abstract

This issue is comprised of 24 papers on host-microbe interactions, focusing on fungi, parasites and viruses. The topics reviewed in the first section on fungi (9 papers) include vesicle trafficking, organelle functions and unconventional secretion in fungal physiology and pathogenicity, endocytosis ...

Author(s)
Dunlap, J. C.; Latgé, J. P.; Duraisingh, M.; Guillén, N.; Saleh, M. C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Current Opinion in Microbiology, 2014, 20, pp 1-175
Abstract

Background: The genus Spiroplasma contains a group of helical, motile, and wall-less bacteria in the class Mollicutes. Similar to other members of this class, such as the animal-pathogenic Mycoplasma and the plant-pathogenic 'Candidatus Phytoplasma', all characterized Spiroplasma species were found ...

Author(s)
Lo WenSui; Chen LingLing; Chung WanChia; Gasparich, G. E.; Kuo ChihHorng
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2013, 14, 22, pp (16 January 2013)

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