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Abstract

In the present study, we have annotated both the immunoglobulin heavy (IgH) and light (IgL) chain genes in the stickleback (Gasterosteus aculeatus), based on the recently released genome data. The IgH gene locus is arranged in a configuration of (Vn-D-J-Cζ-D3-J4-Cμ-Cδ)3-V6-D-J-Cζ, which is...

Author(s)
Bao YongHua; Wang Tao; Guo YongChen; Zhao ZhiHui; Li Ning; Zhao YaoFeng
Publisher
Elsevier Ltd, Oxford, UK
Citation
Fish & Shellfish Immunology, 2010, 28, 1, pp 40-48
Abstract

Background: Interferon regulatory factors (IRFs), which can be identified based on a unique helix-turn-helix DNA-binding domain (DBD) are a large family of transcription factors involved in host immune response, haemotopoietic differentiation and immunomodulation. Despite the identification of 10...

Author(s)
Huang Bei; Qi, Z. T.; Xu Zhen; Nie Pin
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Immunology, 2010, 11, 22, pp (5 May 2010)
Abstract

Background: The development of large genomic resources has become a prerequisite to elucidate the wide scale evolution of genomes and the molecular basis of complex traits. Linkage maps represent a first level of integration and utilization of such resources and the primary framework for molecular...

Author(s)
Guyomard, R.; Mauger, S.; Tabet-Canale, K.; Martineau, S.; Genet, C.; Krieg, F.; Quillet, E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2006, 7, 302, pp (30 November 2006)
Abstract

HOX genes specify cell fate in the anterior-posterior axis of animal embryos. Invertebrate chordates have 1 HOX cluster, but mammals have 4; it has been suggested that cluster duplication facilitated the evolution of vertebrate body plans. In the present work amplification and sequencing of...

Author(s)
Amores, A.; Force, A.; Yan YiLin; Joly, L.; Amemiya, C.; Fritz, A.; Ho, R. K.; Langeland, J.; Prince, V.; Wang YanLing; Westerfield, M.; Ekker, M.; Postlethwait, J. H.
Citation
Science (Washington), 1998, 282, 5394, pp 1711-1714
Abstract

Vertebrate ancestors probably had single copies of genes now found in multiple copies in vertebrates; previous gene mapping studies have suggested that gene duplication occurred by polyploidization. 144 zebrafish (Danio rerio) genes were mapped and the results compared with mammalian maps. Large...

Author(s)
Postlethwait, J. H.; Yan YiLin; Gates, M. A.; Horne, S.; Amores, A.; Brownlie, A.; Donovan, A.; Egan, E. S.; Force, A.; Gong, ZhiYuan; Goutel, C.; Fritz, A.; Kelsh, R.; Knapik, E.; Liao, E.; Paw, B.; Ransom, D.; Singer, A.; Thomson, M.; Abduljabbar, T. S.; Yelick, P.; Beier, D.; Joly, J. S.; Larhammar, D.; Rosa, F.; Westerfield, M.
Citation
Nature Genetics, 1998, 18, 4, pp 345-349

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