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Pepita, a 6-year-old sterilized European domestic cat, kept indoors, was referred to the Internal Medicine Unit of OVIPR due to an acute onset of lethargy, asthenia, and ventroflexion of the neck. The cat had a history of being regularly vaccinated, fed a commercial maintenance diet, and had been...

This article showcases the diverse research efforts at Purdue University College of Veterinary Medicine and their impact on improving animal and human health. The college employs a comparative medicine approach, which involves studying animal diseases to improve understanding and treatment while...

A 6-mo-old, intact male, domestic shorthair cat was referred with a history of poor growth, reluctance to move, and deformation of the nasal profile. The kitten had been fed a diet composed almost exclusively of a complementary pet food and tuna, which was similar to an all-meat diet. We detected...

Ferroptosis is a newly discovered programmed cell death pattern characterized by iron-dependent accumulation of lipid peroxidation. Iron metabolism disorder and oxidative stress play an important role in bacterial infection, and it has been proved that some bacteria could induce host cell death by...

The research was carried out at the Sarafanovo farm, in Chebarkul district, Chelyabinsk region. We established that postpartum endometritis in first-calf heifers is widespread in biogeochemical provinces that contain an excess of nickel and iron. This pathology demonstrates distinct violations of...

Hypocalcemia, defined as total blood calcium concentrations below 2.1 mM, has detrimental impacts on welfare, production and reproduction in dairy cattle. Yet, no cow-side test exists for testing total bovine blood calcium. Here, we modified the split trehalase complementation assay to detect total ...

A balanced diet is essential both for the development and maintenance of a healthy body and for the prevention of many problems such as gastrointestinal disorders, obesity, diabetes, mineral imbalances, or adverse reactions to food. To avoid these disorders, the feed given must be appropriate to...

Periparturient hypocalcemia is a frequently observed metabolic disorder in fresh cows. While the clinical form affects approximately 7% of German dairy cows, nearly half of the multiparous cows exhibit subclinical hypocalcemia. Although both diagnosis and therapy have not changed over the last...

Hypomagnesaemia (grass tetany) is a metabolic disorder of ruminants due to a reduced dietary intake of magnesium (primary deficiency), incorrect digestibility or associated metabolic factors reducing Mg intake (secondary deficiency). Grass tetany is a production disease responsible for important...