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Abstract

In several mammalian species, including mice, round spermatids have been used to produce normal offspring by means of microinsemination techniques. In this study, we examined whether mouse round spermatids retrieved from immature testes undergoing the first wave of spermatogenesis had acquired...

Author(s)
Miki, H.; Lee JiYoung; Inoue, K.; Ogonuki, N.; Noguchi, Y.; Mochida, K.; Kohda, T.; Nagashima, H.; Ishino, F.; Ogura, A.
Publisher
Japanese Society of Animal Reproduction, Tokyo, Japan
Citation
Journal of Reproduction and Development, 2004, 50, 1, pp 131-137
Abstract

In micromanipulation experiments using immature oocytes, final ooplasmic maturation is often compromised because the oocytes are usually first freed from their nurturing cumulus cells. This study was undertaken to determine whether cumulus-free in vitro maturation (IVM) in mice could be improved by ...

Author(s)
Miki, H.; Ogonuki, N.; Inoue, K.; Baba, T.; Ogura, A.
Publisher
Japanese Society of Animal Reproduction, Tokyo, Japan
Citation
Journal of Reproduction and Development, 2006, 52, 2, pp 239-248
Abstract

Sertoli cells play a pivotal role in spermatogenesis through their interactions with germ cells. To set up a strategy for treating male infertility caused by Sertoli cell dysfunction, we developed a Sertoli cell gene transfer system by using an adenovirus vector, which maintained long-term...

Author(s)
Kanatsu-Shinohara, M.; Ogura, A.; Ikegawa, M.; Inoue, K.; Ogonuki, N.; Tashiro, K.; Toyokuni, S.; Honjo, T.; Shinohara, T.
Publisher
National Academy of Sciences, Washington, USA
Citation
Proceedings of the National Academy of Sciences of the United States of America, 2002, 99, 3, pp 1383-1388
Abstract

Mammalian diploid embryos are produced by fusion (fertilization) of specialized germ cells (gametes) from the male and female. The definitely differentiated male germ cells, the spermatozoa, gain the fertilizing ability after maturation in the epididymis. Therefore, under in vivo and conventional ...

Author(s)
Ogura, A.; Inoue, K.; Ogonuki, N.; Suzuki, O.; Mochida, K.; Matsuda, J.
Citation
Journal of Reproduction and Development, 1999, 45, Supplement, pp j37-j44

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