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Abstract

Bacillus Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis (M. bovis), is the lead candidate vaccine for control of bovine tuberculosis (TB) in cattle. However, BCG vaccination sensitises cattle to bovine tuberculin, thus compromising the use of the current bovine TB surveillance...

Author(s)
Jones, G. J.; Konold, T.; Hurley, S.; Holder, T.; Steinbach, S.; Coad, M.; Wedlock, D. N.; Buddle, B. M.; Singh, M.; Vordermeier, H. M.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2022, 12, 7,
Abstract

Cattle vaccination is an attractive approach in compliance with control and eradication programs against Bovine Tuberculosis (bTB). Today, there is no anti bTB vaccine licensed. Two vaccine candidates, Mb?mce2 and Mb?mce2-phoP previously designed were evaluated in BALB/c mice, including the...

Author(s)
Ferrara Muñiz, X.; García, E. A.; Blanco, F. C.; Bigi, F.; Zumárraga, M. J.; Cataldi, A. A.; Eirin, M. E.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Tuberculosis, 2022, 134,
Abstract

Bacille Calmette-Guerin (BCG) is a potential tool in the control of Mycobacterium bovis in European badgers (Meles meles). A five year Test and Vaccinate or Remove (TVR) research intervention project commenced in 2014 using two BCG strains (BCG) Copenhagen 1331 (Years 1-3/ Badger BCG) and BCG Sofia ...

Author(s)
Courcier, E. A.; Collins, S. F.; McCormick, C. M.; Arnold, M. E.; Corbett, D. M.; Ford, T.; McGeown, C. F.; Barry, C.; Kirke, R.; Menzies, F. D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2022, 40, 34, pp 4972-4978
AbstractFull Text

Culling the main wildlife host of bovine tuberculosis in Great Britain (GB) and Ireland, the European badger (Meles meles), has been employed in both territories to reduce infections in cattle. In GB, this has been controversial, with results suggesting that culling induces disturbance to badger...

Author(s)
Allen, A.; Milne, G.; McCormick, C.; Collins, S.; O'Hagan, M.; Skuce, R.; Trimble, N.; Harwood, R.; Menzies, F.; Byrne, A. W.
Publisher
British Ecological Society, London, UK
Citation
Ecological Solutions and Evidence, 2022, 3, e12165,
Abstract

Tick vaccines are necessary as part of a One Health approach for the control of tick infestations and tick-borne diseases. Subolesin (SUB, also known as 4D8) is a tick protective antigen that has shown efficacy in vaccine formulations for the control of ectoparasite infestations and pathogen...

Author(s)
Kasaija, P. D.; Contreras, M.; Kabi, F.; Mugerwa, S.; Garrido, J. M.; Gortazar, C.; Fuente, J. de la
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2022, 40, 32, pp 4564-4573
Abstract

Bovine tuberculosis is a costly disease shared by cattle and badgers, and to reduce the infection in cattle some form of badger management would be necessary. Here we compare the results of a badger field trial where test-postive badgers are culled and test-negative badgers vaccinated (a TVR...

Author(s)
Smith, G. C.; Budgey, R.; Gold, S.
Publisher
Society for Veterinary Epidemiology and Preventive Medicine, Belfast, UK
Citation
Proceedings of the Society for Veterinary Epidemiology and Preventive Medicine annual meeting, Belfast, Northern Ireland, UK, 23-25 March 2022 , 2022, pp 208-217
Abstract

In Europe, animal tuberculosis (TB) due to Mycobac-terium bovis involves multi-host communities that include cattle and wildlife species, such as wild boar (Sus scrofa), badgers (Meles meles) and red deer (Cervus elaphus). Red fox (Vulpes vulpes) infections have also been recently reported in some...

Author(s)
Richomme, C.; Lesellier, S.; Salguero, F. J.; Barrat, J. L.; Boucher, J. M.; Reyes-Reyes, J. D.; Hénault, S.; Cruz, K. de; Tambosco, J.; Michelet, L.; Boutet, J.; Elahi, R.; Lyashchenko, K. P.; O'Halloran, C.; Balseiro, A.; Boschiroli, M. L.
Publisher
International Fur Animal Scientific Association, Tjele, Denmark
Citation
Scientifur, 2022, 46, 2, pp 53-54
AbstractFull Text

Bovine tuberculosis (bTB) is a zoonotic disease caused mainly by Mycobacterium bovis, which is associated with major economic losses for milk and meat producers. The objective of this trial was to assess the efficacy of the BCG Russia strain in a cohort study performed under field conditions, with...

Author(s)
Ábalos, P.; Valdivieso, N.; Val, B. P. de; Vordermeier, M.; Benavides, M. B.; Alegría-Morán, R.; Saadi, K.; Wistuba, M.; Ortega, C.; Sánchez, N.; Retamal, P.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2022, 12, 9,
AbstractFull Text

Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components of bTB and initiates antigen-presenting cells to mediate humoral immunity. Evaluating the...

Author(s)
Song ShengNan; Zhang Qian; Yang Hang; Guo Jia; Xu MingGuo; Yang NingNing; Yi JihAi; Wang Zhen; Chen ChuangFu
Publisher
Korean Society of Veterinary Science, Seoul, Korea Republic
Citation
Journal of Veterinary Science, 2022, 23, 3,
Abstract

Bovine tuberculosis (bTB) continues to be a pathogen of concern in several countries globally. Analysis of areas that have higher incidences of bTB outbreaks has demonstrated how risk is not equally distributed, and local data collection, analysis and participatory engagement is required to develop ...

Author(s)
Clarke, A.; Byrne, A. W.; Maher, J.; Ryan, E.; Farrell, F.; McSweeney, C.; Barrett, D.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2022, 8, February,

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