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Gut commensal bacteria could play a role in influencing the outcome of oral BCG vaccination
Field trials recommended by the EU would have to be extremely large to show a benefit of vaccination, researchers say
The mutation accumulation theory of senescence predicts that age-related deterioration of fitness can be exaggerated when inbreeding causes homozygosity for deleterious alleles. A vital component of fitness, in natural populations, is the incidence and progression of disease. Evidence is growing...
Increasing crossbreeding of relatives promotes inbreeding which, in turn, can cause a reduction in fitness and the emergence of a phenomenon known as inbreeding depression. Benton et al., [Benton, C. H., 2018] used the badger (Meles meles) - Mycobacterium bovis model system to study the...
Estimates of disease prevalence in any host population are complicated by uncertainty in the outcome of diagnostic tests on individuals. In the absence of gold standard diagnostics (tests that give neither false positives nor false negatives), Bayesian latent class inference can be applied to...