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Abstract

Background: Bovine tuberculosis (bTB) caused by Mycobacterium bovis is the most serious endemic disease affecting livestock in the UK. The European badger (Meles meles) is the most important wildlife reservoir of bTB transmission to cattle, making eradication particularly difficult. In this...

Author(s)
Stedman, A.; Motes, C. M. de; Lesellier, S.; Dalley, D.; Chambers, M.; Gutierrez-Merino, J.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Microbiology, 2018, 18, 74, pp (13 July 2018)
Abstract

European badgers (Meles meles) are considered to be an important reservoir of infection for Mycobacterium bovis and are implicated in the transmission of tuberculosis to cattle in Ireland and Great Britain. Accurate tests are required for tuberculosis surveillance in badger populations and to...

Author(s)
Lesellier, S.; Corner, L.; Costello, E.; Sleeman, P.; Lyashchenko, K.; Greenwald, R.; Esfandiari, J.; Mahavir Singh; Hewinson, R. G.; Chambers, M.; Gormley, E.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2008, 122, 1/2, pp 35-45
Abstract

European badgers (Meles meles) are a reservoir host of Mycobacterium bovis and are implicated in the transmission of tuberculosis to cattle in Ireland and Great Britain. The development of a vaccine for use in badgers is considered a key element of any campaign to eradicate the disease in livestock ...

Author(s)
Lesellier, S.; Corner, L.; Costello, E.; Lyashchenko, K.; Greenwald, R.; Esfandiari, J.; Mahavir Singh; Hewinson, R. G.; Chambers, M.; Gormley, E.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Vaccine, 2009, 27, 3, pp 402-409
Abstract

The control of tuberculosis (TB) in cattle in the UK and Ireland is compromised by transmission of Mycobacterium bovis to cattle from the European badger (Meles meles), which acts as a wildlife reservoir. Vaccination of badgers could potentially contribute to TB control but the only licensed...

Author(s)
Palphramand, K.; Delahay, R.; Robertson, A.; Gowtage, S.; Williams, G. A.; McDonald, R. A.; Chambers, M.; Carter, S. P.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2017, 35, 34, pp 4402-4407
Abstract

In this paper we report the development of a sensitive and specific assay for the detection of tuberculosis (TB) in European badgers (Meles meles), based on the stimulation of lymphocytes in whole-blood culture and the subsequent detection of gamma-interferon (IFNγ) by sandwich ELISA. The...

Author(s)
Dalley, D.; Davé, D.; Lesellier, S.; Palmer, S.; Crawshaw, T.; Hewinson, R. G.; Chambers, M.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Tuberculosis, 2008, 88, 3, pp 235-243

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