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Abstract

Recent studies suggest that badgers may be a potential reservoir of Mycobacterium bovis infection for cattle in Northern Spain. The objective of this study was to investigate potential epidemiological links between cattle and badgers. Culture and molecular typing data were available for cattle...

Author(s)
Balseiro, A.; González-Quirós, P.; Rodríguez, Ó.; Copano, M. F.; Merediz, I.; Juan, L. de; Chambers, M. A.; Delahay, R. J.; Marreros, N.; Royo, L. J.; Bezos, J.; Prieto, J. M.; Gortázar, C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2013, 197, 3, pp 739-745
Abstract

European badgers (Meles meles) are a wildlife reservoir for Mycobacterium bovis (M. bovis) in parts of England, Wales and Ireland, constituting a potential source of tuberculosis (TB) infection for cattle. Vaccination of badgers against TB is one of the tools available for helping reduce the...

Author(s)
Perrett, S.; Lesellier, S.; Rogers, F.; Williams, G. A.; Gowtage, S.; Palmer, S.; Dalley, D.; Davé, D.; Weyer, U.; Wood, E.; Salguero, F. J.; Nunez, A.; Reed, N.; Chambers, M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2018, 36, 15, pp 1990-1995
Abstract

We describe epidemiological trends in Mycobacterium bovis infection in an undisturbed wild badger (Meles meles) population. Data were derived from the capture, clinical sampling and serological testing of 1803 badgers over 9945 capture events spanning 24 years. Incidence and prevalence increased...

Author(s)
Delahay, R. J.; Walker, N.; Smith, G. S.; Wilkinson, D.; Clifton-Hadley, R. S.; Cheeseman, C. L.; Tomlinson, A. J.; Chambers, M. A.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Epidemiology and Infection, 2013, 141, 7, pp 1445-1456
Abstract

The behaviour of certain infected individuals within socially structured populations can have a disproportionately large effect on the spatio-temporal distribution of infection. Endemic infection with Mycobacterium bovis in European badgers (Meles meles) in Great Britain and Ireland is an important ...

Author(s)
Tomlinson, A. J.; Chambers, M. A.; Carter, S. P.; Wilson, G. J.; Smith, G. C.; McDonald, R. A.; Delahay, R. J.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Epidemiology and Infection, 2013, 141, 7, pp 1458-1466
Abstract

In developing an oral bait BCG vaccine against tuberculosis in badgers we wanted to understand the conditions of the gastrointestinal tract and their impact on vaccine viability. Conditions mimicking stomach and small-intestine caused substantial reduction in BCG viability. We performed in vivo...

Author(s)
Williams, G. A.; Koenen, M. E.; Havenaar, R.; Wheeler, P.; Gowtage, S.; Lesellier, S.; Chambers, M. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 4, pp e0214859
Abstract

In the UK and the Republic of Ireland, the European badger (Meles meles) is a maintenance host for Mycobacterium bovis, and may transmit the infection to cattle causing bovine tuberculosis (TB). Vaccination of badgers using an injectable Bacillus Calmette-Guerin (BCG) vaccine is undertaken in some...

Author(s)
Robertson, A.; Delahay, R. J.; McDonald, R. A.; Aylett, P.; Henderson, R.; Gowtage, S.; Chambers, M. A.; Carter, S. P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2016, 135, pp 95-101
Abstract

The European badger (Meles meles) is a reservoir host of Mycobacterium bovis and responsible for a proportion of the tuberculosis (TB) cases seen in cattle in the United Kingdom and Republic of Ireland. An injectable preparation of the bacillus Calmette-Guérin (BCG) vaccine is licensed for use in ...

Author(s)
Chambers, M. A.; Aldwell, F.; Williams, G. A.; Palmer, S.; Gowtage, S.; Ashford, R.; Dalley, D. J.; Davé, D.; Weyer, U.; Salguero, F. J.; Nunez, A.; Nadian, A. K.; Crawshaw, T.; Corner, L. A. L.; Lesellier, S.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Cellular and Infection Microbiology, 2017, 7, January, pp 6
Abstract

Bovine tuberculosis (TB) continues to be an intractable problem in many countries, particularly where "test and slaughter" policies cannot be implemented or where wildlife reservoirs of Mycobacterium bovis infection serve as a recurrent source of infection for domestic livestock. Alternative...

Author(s)
Buddle, B. M.; Vordermeier, H. M.; Chambers, M. A.; Klerk-Lorist, L. M. de
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, October, pp 259
Abstract

The diagnosis and control of Mycobacterium bovis infection (bovine tuberculosis: TB) continues to present huge challenges to the British cattle industry. A clearer understanding of the magnitude and duration of immune response to M. bovis infection in the European badger (Meles meles) - a wildlife...

Author(s)
Buzdugan, S. N.; Chambers, M. A.; Delahay, R. J.; Drewe, J. A.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Epidemiology and Infection, 2017, 145, 15, pp 3204-3213
Abstract

The oral vaccination of wild badgers (Meles meles) with live Bacillus Calmette-Guérin (BCG) is one of the tools being considered for the control of bovine tuberculosis (caused by Mycobacterium bovis) in the UK. The design of a product for oral vaccination requires that numerous, and often...

Author(s)
Gowtage, S.; Williams, G. A.; Henderson, R.; Aylett, P.; MacMorran, D.; Palmer, S.; Robertson, A.; Lesellier, S.; Carter, S. P.; Chambers, M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2017, 35, 6, pp 987-992

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