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Abstract

In the UK and Ireland, Bacille Calmette-Guérin (BCG) vaccination of badgers has been suggested as one of a number of strategies to control or even eradicate Mycobacterium bovis infection in badgers. In this manuscript, we present the results of a badger field trial conducted in Ireland and discuss...

Author(s)
Aznar, I.; Frankena, K.; More, S. J.; O'Keeffe, J.; McGrath, G.; Jong, M. C. M. de
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2018, 149, pp 29-37
Abstract

European badgers (Meles meles) are a wildlife reservoir for Mycobacterium bovis (M. bovis) in parts of England, Wales and Ireland, constituting a potential source of tuberculosis (TB) infection for cattle. Vaccination of badgers against TB is one of the tools available for helping reduce the...

Author(s)
Perrett, S.; Lesellier, S.; Rogers, F.; Williams, G. A.; Gowtage, S.; Palmer, S.; Dalley, D.; Davé, D.; Weyer, U.; Wood, E.; Salguero, F. J.; Nunez, A.; Reed, N.; Chambers, M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2018, 36, 15, pp 1990-1995
Abstract

European badgers (Meles meles) in Ireland and the UK are a reservoir for Mycobacterium bovis, the causative agent of bovine tuberculosis (TB). A number of interventions have been evaluated in attempts to control bovine TB within badger populations, and many of which rely on the capture of badgers....

Author(s)
Martin, L. E. R.; Byrne, A. W.; O'Keeffe, J.; Miller, M. A.; Olea-Popelka, F. J.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
European Journal of Wildlife Research, 2017, 63, 1, pp 30
Abstract

In the UK and the Republic of Ireland, the European badger (Meles meles) is a maintenance host for Mycobacterium bovis, and may transmit the infection to cattle causing bovine tuberculosis (TB). Vaccination of badgers using an injectable Bacillus Calmette-Guerin (BCG) vaccine is undertaken in some...

Author(s)
Robertson, A.; Delahay, R. J.; McDonald, R. A.; Aylett, P.; Henderson, R.; Gowtage, S.; Chambers, M. A.; Carter, S. P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2016, 135, pp 95-101
Abstract

Because biological systems are complex, management interventions occasionally have unintended adverse consequences. For example, attempts to control bovine tuberculosis (TB) by culling badgers Meles meles have, under some circumstances, inadvertently increased cattle TB risks. Such harmful effects...

Author(s)
Woodroffe, R.; Donnelly, C. A.; Ham, C.; Jackson, S. Y. B.; Moyes, K.; Chapman, K.; Stratton, N. G.; Cartwright, S. J.
Publisher
Wiley, Oxford, UK
Citation
Journal of Applied Ecology, 2017, 54, 3, pp 718-725
Abstract

Computer modeling has a long history of association with epidemiology, and has improved our understanding of the theory of disease dynamics and provided insights into wildlife disease management. A summary of badger bovine TB models and their role in decision making is presented, from a simple...

Author(s)
Smith, G. C.; Delahay, R. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, November, pp 276
Abstract

In developing an oral bait BCG vaccine against tuberculosis in badgers we wanted to understand the conditions of the gastrointestinal tract and their impact on vaccine viability. Conditions mimicking stomach and small-intestine caused substantial reduction in BCG viability. We performed in vivo...

Author(s)
Williams, G. A.; Koenen, M. E.; Havenaar, R.; Wheeler, P.; Gowtage, S.; Lesellier, S.; Chambers, M. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 4, pp e0214859
Abstract

Tuberculosis in animals is caused principally by infection with Mycobacterium bovis and the potential for transmission of infection to humans is often the fundamental driver for surveillance of disease in livestock and wild animals. However, with such a vast array of species susceptible to...

Author(s)
Gormley, E.; Corner, L. A. L.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, January, pp 247
Abstract

The oral vaccination of wild badgers (Meles meles) with live Bacillus Calmette-Guérin (BCG) is one of the tools being considered for the control of bovine tuberculosis (caused by Mycobacterium bovis) in the UK. The design of a product for oral vaccination requires that numerous, and often...

Author(s)
Gowtage, S.; Williams, G. A.; Henderson, R.; Aylett, P.; MacMorran, D.; Palmer, S.; Robertson, A.; Lesellier, S.; Carter, S. P.; Chambers, M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2017, 35, 6, pp 987-992
Abstract

A long-term research programme has been underway in Ireland to evaluate the usefulness of badger vaccination as part of the national bTB (bovine tuberculosis) control strategy. This culminated in a field trial which commenced in county Kilkenny in 2009 to determine the effects of badger vaccination ...

Author(s)
Aznar, I.; Frankena, K.; More, S. J.; Whelan, C.; Martin, W.; Gormley, E.; Corner, L. A. L.; Murphy, D.; Jong, M. C. M. de
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2014, 9, 7, pp e100139

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