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Abstract

In developing an oral bait BCG vaccine against tuberculosis in badgers we wanted to understand the conditions of the gastrointestinal tract and their impact on vaccine viability. Conditions mimicking stomach and small-intestine caused substantial reduction in BCG viability. We performed in vivo...

Author(s)
Williams, G. A.; Koenen, M. E.; Havenaar, R.; Wheeler, P.; Gowtage, S.; Lesellier, S.; Chambers, M. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 4, pp e0214859
Abstract

European badgers (Meles meles) have been identified as wildlife reservoirs for Mycobacterium bovis in the UK and Ireland, and may also have a role in the epidemiology of animal tuberculosis in other European regions. Thus, detection of M. bovis-infected badgers may be required for the purposes of...

Author(s)
Infantes-Lorenzo, J. A.; Dave, D.; Moreno, I.; Anderson, P.; Lesellier, S.; Gormley, E.; Dominguez, L.; Balseiro, A.; Gortázar, C.; Dominguez, M.; Salguero, F. J.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2019, 5, 1, pp 61-69
Abstract

Background: Bovine tuberculosis (bTB, caused by infection with Mycobacterium bovis) is endemic in the Irish cattle population, and the subject of a national eradication programme since the late 1950s. During 2014, a substantial area-level bTB outbreak developing in north County Sligo, necessitating ...

Author(s)
Doyle, R.; Clegg, T. A.; McGrath, G.; Tratalos, J.; Barrett, D.; Lee, A.; More, S. J.
Publisher
BioMed Central Ltd, London, UK
Citation
Irish Veterinary Journal, 2018, 71, 24, pp (28 November 2018)
Abstract

Host resistance and infectivity are genetic traits affecting infectious disease transmission. This Perspective discusses the potential exploitation of genetic variation in cattle infectivity, in addition to resistance, to reduce the risk, and prevalence of bovine tuberculosis (bTB). In bTB,...

Author(s)
Tsairidou, S.; Allen, A.; Banos, G.; Coffey, M.; Anacleto, O.; Byrne, A. W.; Skuce, R. A.; Glass, E. J.; Woolliams, J. A.; Doeschl-Wilson, A. B.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, December, pp 310
Abstract

Computer modeling has a long history of association with epidemiology, and has improved our understanding of the theory of disease dynamics and provided insights into wildlife disease management. A summary of badger bovine TB models and their role in decision making is presented, from a simple...

Author(s)
Smith, G. C.; Delahay, R. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, November, pp 276
Abstract

Mycobacterium bovis infection was first described in free-ranging wildlife in France in 2001, with subsequent detection in hunter-harvested ungulates and badgers in areas where outbreaks of bovine tuberculosis (TB) were also detected in cattle. Increasing concerns regarding TB in wildlife led the...

Author(s)
Réveillaud, É.; Desvaux, S.; Boschiroli, M. L.; Hars, J.; Faure, É.; Fediaevsky, A.; Cavalerie, L.; Chevalier, F.; Jabert, P.; Poliak, S.; Tourette, I.; Hendrikx, P.; Richomme, C.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, October, pp 262
Abstract

Bovine tuberculosis (TB) continues to be an intractable problem in many countries, particularly where "test and slaughter" policies cannot be implemented or where wildlife reservoirs of Mycobacterium bovis infection serve as a recurrent source of infection for domestic livestock. Alternative...

Author(s)
Buddle, B. M.; Vordermeier, H. M.; Chambers, M. A.; Klerk-Lorist, L. M. de
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, October, pp 259
Abstract

Background: Bovine tuberculosis (bTB) is a zoonotic disease of cattle caused by Mycobacterium bovis, widespread in England and Wales. It has high incidence towards the South West of England and Wales, with much lower incidence to the East and North. A stochastic simulation model was developed to...

Author(s)
Birch, C. P. D.; Goddard, A.; Tearne, O.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2018, 14, 273, pp (4 September 2018)
Abstract

Mycobacterium bovis is the main cause of bovine tuberculosis and its eradication is proving difficult in many countries because of wildlife reservoirs, including European badgers (Meles meles) in the UK Ireland. Following the development of badger specific immunological reagents, many studies have...

Author(s)
Lesellier, S.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Comparative Immunology, Microbiology & Infectious Diseases, 2018, 61, pp 9-15
Abstract

In the French departments of Pyrénées-Atlantiques and Landes, bovine tuberculosis (bTB) due to Mycobacterium bovis is detected within cattle farms through prophylactic measures and within wild populations through a devoted surveillance system. Within the infected area at the border of these two...

Author(s)
Bouchez-Zacria, M.; Courcoul, A.; Durand, B.
Publisher
Association pour l'Étude de l'Épidémiologie des Maladies Animales, Maisons-Alfort, France
Citation
Épidémiologie et Santé Animale, 2018, No.74, pp 69-79

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