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Abstract

In developing an oral bait BCG vaccine against tuberculosis in badgers we wanted to understand the conditions of the gastrointestinal tract and their impact on vaccine viability. Conditions mimicking stomach and small-intestine caused substantial reduction in BCG viability. We performed in vivo...

Author(s)
Williams, G. A.; Koenen, M. E.; Havenaar, R.; Wheeler, P.; Gowtage, S.; Lesellier, S.; Chambers, M. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 4, pp e0214859
Abstract

European badgers (Meles meles) have been identified as wildlife reservoirs for Mycobacterium bovis in the UK and Ireland, and may also have a role in the epidemiology of animal tuberculosis in other European regions. Thus, detection of M. bovis-infected badgers may be required for the purposes of...

Author(s)
Infantes-Lorenzo, J. A.; Dave, D.; Moreno, I.; Anderson, P.; Lesellier, S.; Gormley, E.; Dominguez, L.; Balseiro, A.; Gortázar, C.; Dominguez, M.; Salguero, F. J.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2019, 5, 1, pp 61-69
Abstract

Culling wildlife to control disease can lead to both decreases and increases in disease levels, with apparently conflicting responses observed, even for the same wildlife-disease system. There is therefore a pressing need to understand how culling design and implementation influence culling's...

Author(s)
Prentice, J. C.; Fox, N. J.; Hutchings, M. R.; White, P. C. L.; Davidson, R. S.; Marion, G.
Publisher
The Royal Society, London, UK
Citation
Journal of the Royal Society Interface, 2019, 16, 152, pp 20180901
Abstract

In Great Britain (GB) overall, approximately nine new incidents of bovine TB (bTB) were detected in 2017 for every 100 herds that underwent a full year of surveillance, a slight increase from the 2016 figure of 8.4. There was substantial variation across GB at country, surveillance risk area and...

Author(s)
Perrin, L. D.; Harris, K. A.; Lawes, J. R.; Frost, S.; Brouwer, A.; Dale, J.; Palkopoulou, E.; Upton, P. A.
Publisher
BMJ Publishing Group, London, UK
Citation
Veterinary Record, 2019, 184, 12, pp 371-378
Abstract

Background: Bovine tuberculosis (bTB) caused by Mycobacterium bovis is the most serious endemic disease affecting livestock in the UK. The European badger (Meles meles) is the most important wildlife reservoir of bTB transmission to cattle, making eradication particularly difficult. In this...

Author(s)
Stedman, A.; Motes, C. M. de; Lesellier, S.; Dalley, D.; Chambers, M.; Gutierrez-Merino, J.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Microbiology, 2018, 18, 74, pp (13 July 2018)
Abstract

Since 2009, Poland has been recognized as a country officially free of bovine tuberculosis (BTB). However, new outbreaks are each year quoted. In many countries it has been shown that badgers (Meles meles) are a vector of Mycobacterium bovis/caprae (M. bovis/caprae) and a source of bovine...

Author(s)
Lipiec, M.; Nowakowski, K.; Radulski, Ł.; Iwaniak, W.; Ważna, A.
Publisher
Instytut Medycyny WSI im. W. Chodźki, Lublin, Poland
Citation
Annals of Agricultural and Environmental Medicine, 2018, 25, 3, pp 409-410
Abstract

Background: Bovine tuberculosis (bTB, caused by infection with Mycobacterium bovis) is endemic in the Irish cattle population, and the subject of a national eradication programme since the late 1950s. During 2014, a substantial area-level bTB outbreak developing in north County Sligo, necessitating ...

Author(s)
Doyle, R.; Clegg, T. A.; McGrath, G.; Tratalos, J.; Barrett, D.; Lee, A.; More, S. J.
Publisher
BioMed Central Ltd, London, UK
Citation
Irish Veterinary Journal, 2018, 71, 24, pp (28 November 2018)
Abstract

Host resistance and infectivity are genetic traits affecting infectious disease transmission. This Perspective discusses the potential exploitation of genetic variation in cattle infectivity, in addition to resistance, to reduce the risk, and prevalence of bovine tuberculosis (bTB). In bTB,...

Author(s)
Tsairidou, S.; Allen, A.; Banos, G.; Coffey, M.; Anacleto, O.; Byrne, A. W.; Skuce, R. A.; Glass, E. J.; Woolliams, J. A.; Doeschl-Wilson, A. B.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, December, pp 310
Abstract

Computer modeling has a long history of association with epidemiology, and has improved our understanding of the theory of disease dynamics and provided insights into wildlife disease management. A summary of badger bovine TB models and their role in decision making is presented, from a simple...

Author(s)
Smith, G. C.; Delahay, R. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, November, pp 276
Abstract

Mycobacterium bovis infection was first described in free-ranging wildlife in France in 2001, with subsequent detection in hunter-harvested ungulates and badgers in areas where outbreaks of bovine tuberculosis (TB) were also detected in cattle. Increasing concerns regarding TB in wildlife led the...

Author(s)
Réveillaud, É.; Desvaux, S.; Boschiroli, M. L.; Hars, J.; Faure, É.; Fediaevsky, A.; Cavalerie, L.; Chevalier, F.; Jabert, P.; Poliak, S.; Tourette, I.; Hendrikx, P.; Richomme, C.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, October, pp 262

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