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Abstract

In the UK and Ireland, Bacille Calmette-Guérin (BCG) vaccination of badgers has been suggested as one of a number of strategies to control or even eradicate Mycobacterium bovis infection in badgers. In this manuscript, we present the results of a badger field trial conducted in Ireland and discuss...

Author(s)
Aznar, I.; Frankena, K.; More, S. J.; O'Keeffe, J.; McGrath, G.; Jong, M. C. M. de
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2018, 149, pp 29-37
Abstract

Mycobacterium bovis is the main cause of bovine tuberculosis and its eradication is proving difficult in many countries because of wildlife reservoirs, including European badgers (Meles meles) in the UK Ireland. Following the development of badger specific immunological reagents, many studies have...

Author(s)
Lesellier, S.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Comparative Immunology, Microbiology & Infectious Diseases, 2018, 61, pp 9-15
Abstract

The use of agricultural resources or environments by wildlife may result in opportunities for transmission of infections amongst wild animals, livestock and humans. Targeted use of biosecurity measures may therefore reduce disease risks, although this requires practical knowledge of where such...

Author(s)
Robertson, A.; Judge, J.; Wilson, G. J.; Vernon, I. J.; Delahay, R. J.; McDonald, R. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 5, pp e0216953
Abstract

Background: The European badger is an important wildlife reservoir of Mycobacterium bovis implicated in the spread of bovine tuberculosis in the United Kingdom and Ireland. Infected badgers are known to shed M. bovis in their urine and faeces, which may contaminate the environment. To aid bovine...

Author(s)
Stewart, L. D.; Tort, N.; Meakin, P.; Argudo, J. M.; Nzuma, R.; Reid, N.; Delahay, R. J.; Ashford, R.; Montgomery, W. I.; Grant, I. R.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2017, 13, 131, pp (12 May 2017)
Abstract

European badgers (Meles meles) in Ireland and the UK are a reservoir for Mycobacterium bovis, the causative agent of bovine tuberculosis (TB). A number of interventions have been evaluated in attempts to control bovine TB within badger populations, and many of which rely on the capture of badgers....

Author(s)
Martin, L. E. R.; Byrne, A. W.; O'Keeffe, J.; Miller, M. A.; Olea-Popelka, F. J.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
European Journal of Wildlife Research, 2017, 63, 1, pp 30
Abstract

In the UK and the Republic of Ireland, the European badger (Meles meles) is a maintenance host for Mycobacterium bovis, and may transmit the infection to cattle causing bovine tuberculosis (TB). Vaccination of badgers using an injectable Bacillus Calmette-Guerin (BCG) vaccine is undertaken in some...

Author(s)
Robertson, A.; Delahay, R. J.; McDonald, R. A.; Aylett, P.; Henderson, R.; Gowtage, S.; Chambers, M. A.; Carter, S. P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2016, 135, pp 95-101
Abstract

Because biological systems are complex, management interventions occasionally have unintended adverse consequences. For example, attempts to control bovine tuberculosis (TB) by culling badgers Meles meles have, under some circumstances, inadvertently increased cattle TB risks. Such harmful effects...

Author(s)
Woodroffe, R.; Donnelly, C. A.; Ham, C.; Jackson, S. Y. B.; Moyes, K.; Chapman, K.; Stratton, N. G.; Cartwright, S. J.
Publisher
Wiley, Oxford, UK
Citation
Journal of Applied Ecology, 2017, 54, 3, pp 718-725
Abstract

Landscape epidemiology analyses how environmental characteristics influence pathogen transmission between hosts of one or several species, by inducing constraints on space use by hosts, and/or on pathogen survival in the environment. Here, we analysed how environmental variables could be associated ...

Author(s)
Bouchez-Zacria, M.; Courcoul, A.; Jabert, P.; Richomme, C.; Durand, B.
Publisher
Springer Berlin, Heidelberg, Germany
Citation
European Journal of Wildlife Research, 2017, 63, 5, pp 74
Abstract

Computer modeling has a long history of association with epidemiology, and has improved our understanding of the theory of disease dynamics and provided insights into wildlife disease management. A summary of badger bovine TB models and their role in decision making is presented, from a simple...

Author(s)
Smith, G. C.; Delahay, R. J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, November, pp 276
Abstract

In developing an oral bait BCG vaccine against tuberculosis in badgers we wanted to understand the conditions of the gastrointestinal tract and their impact on vaccine viability. Conditions mimicking stomach and small-intestine caused substantial reduction in BCG viability. We performed in vivo...

Author(s)
Williams, G. A.; Koenen, M. E.; Havenaar, R.; Wheeler, P.; Gowtage, S.; Lesellier, S.; Chambers, M. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 4, pp e0214859

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