Newborn piglets are susceptible to a highly contagious enteritis caused by the porcine epidemic diarrhea virus (PEDV), associated with high levels of mortality worldwide. There is pressing need for a rapid, safe, and cost-effective vaccine to safeguard pigs from getting infected by PEDV. PEDV...
Author(s)
Sohn EunJu; Kang Hyangju; Min Kyungmin; Park Minhee; Kim JuHun; Seo HwiWon; Lee SangJoon; Kim Heeyeon; Tark Dongseob; Cho HoSeong; Choi BoHwa; Oh Yeonsu
Publisher
MDPI AG, Basel, Switzerland
Citation
Vaccines, 2023, 11, 5,
[Objective] The C3d gene of camel complement was cloned and its sequence characteristics were analyzed to provide a basis for the study of its adjuvant effect. [Methods] Total RNA was extracted from camel liver using Trizol reagent, and cDNA was obtained by reverse transcription. C3d pecific...
Author(s)
Nasibai, A.; Gao XiaoJuan; Kunduziayi, A.; Li JiangWei
Publisher
Editorial Department of Xinjiang Agricultural Sciences, Urumqi, China
Citation
Xinjiang Agricultural Sciences, 2023, 60, 2, pp 493-500
Streptococcus suis is a zoonotic pathogen causing disease in both animals and humans, and the emergence of increasingly resistant bacteria to antimicrobial agents has become a significant challenge globally. The objective of this study was to investigate the genetic basis for declining...
Author(s)
Lunha, K.; Chumpol, W.; Jiemsup, S.; Samngamnim, S.; Assavacheep, P.; Yongkiettrakul, S.
Publisher
MDPI AG, Basel, Switzerland
Citation
Antibiotics, 2023, 12, 1,
Pseudorabies virus (PRV) is the pathogen of pseudorabies (PR), which belongs to the alpha herpesvirus subfamily with a double stranded DNA genome encoding approximately 70 proteins. PRV has many non-essential regions for replication, has a strong capacity to accommodate foreign genes, and more...
Author(s)
Zhou Mo; Abid, M.; Cao ShiNuo; Zhu ShanYuan
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2023, 15, 2,
Like other alpha herpesviruses, pseudorabies virus (PRV) establishes lifelong latency in trigeminal ganglionic (TG) neurons. Upon stress, the latent viruses in the TG neurons reactivate and are transported anterograde from the neuron cell bodies to the nerve endings in the nasal mucosa, where they...
Author(s)
Pavulraj, S.; Stout, R. W.; Paulsen, D. B.; Chowdhury, S. I.
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2023, 15, 2,
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of endo-1,4-β-D-mannanase (Hemicell® HT/HT-L) produced by a genetically-modified strain of Paenibacillus lentus (DSM 33618) as a zootechnical feed additive for chickens and...
Author(s)
Bampidis, V.; Azimonti, G.; Bastos, M. de L.; Christensen, H.; Durjava, M.; Dusemund, B.; Kouba, M.; López-Alonso, M.; López Puente, S.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Anguita, M.; Brozzi, R.; García-Cazorla, Y.; Ortuño, J.; Pettenati, E.; Vettori, M. V.; Revez, J.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2023, 21, 2,
Porcine deltacoronavirus is an evolving coronavirus that primarily infects the intestine and may lead to intestinal disease in piglets. Up to now, no commercial vaccination is readily accessible to protect against the spread of PDCoV. Lactococcus lactis has been shown to have good immune efficacy...
Author(s)
Zhai KaiGe; Zhang ZhongWang; Liu XinSheng; Lv JianLiang; Zhang LiPing; Li JiaHao; Ma ZhongYuan; Wang YongLu; Guo HuiChen; Zhang YongGuang; Pan Li
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Virology, 2023, 578, pp 180-189
Bone morphogenetic protein 15 (BMP15) is an X-linked gene encoding an oocyte secreted factor, which plays varied functions in the female fertility between mono-ovulatory and poly-ovulatory mammalian species. We previously found that knockout of BMP15 completely blocked porcine follicular...
Author(s)
Jiang TianTuan; Wen KeYing; Liao Alian; Wang YiXian; Jiao YaFei; Guo JinMing; Chen YaoSheng; He ZuYong; Cong PeiQing
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2023, 198, pp 241-249
Efficient and stable expression of foreign genes in cells and transgenic animals is important for gain-of-function studies and the establishment of bioreactors. Safe harbor loci in the animal genome enable consistent overexpression of foreign genes, without side effects. However, relatively few...
Author(s)
Xiang GuangMing; Zhang XiuLing; Xu ChangJiang; Fan ZiYao; Xu Kui; Wang Nan; Wang Yue; Che JingJing; Xu SongSong; Mu YuLian; Li Kui; Liu ZhiGuo
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Journal of Integrative Agriculture, 2023, 22, 1, pp 202-213
Transgene-free method without monoclonal selection