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News Article

Transgene-free method without monoclonal selection

Date
5 April 2022
News Article

Novel approach could help improve understanding of how infectious agents interact with the immune system of livestock and reduce the use of animals in research

Date
9 February 2022
Abstract

Gene-editing holds promise as a new technique for growth promotion in livestock, especially in the face of increased opposition to traditional methods of growth promotion like feed additives. However, to date, there has been only limited progress toward models of growth promotion through ...

Author(s)
Dilger, A. C.; Chen, X.; Honegger, L. T.; Marron, B. M.; Beever, J. E.
Publisher
BioMed Central Ltd, London, UK
Citation
CABI Agriculture and Bioscience, 2022, 3, 36,
Abstract

The selection and introduction of disease resistance genes in livestock not only provide health benefits to animals but opportunities for breeders and farmers to meet the growing demand for high-quality meat and milk while reducing agriculture's footprint on the environment. As traditional methods...

Author(s)
Cigan, A. M.; Knap, P. W.
Publisher
BioMed Central Ltd, London, UK
Citation
CABI Agriculture and Bioscience, 2022, 3, 34,
Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of lactic acid produced by a non-genetically modified strain of Weizmannia coagulans (synonym of ...

Author(s)
Azimonti, G.; Bampidis, V.; Bastos, M. de L.; Christensen, H.; Dusemund, B.; Durjava, M. F.; Kouba, M.; López-Alonso, M.; Puente, S. L.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Maradona, M. P.; Anguita, M.; Galobart, J.; Pettenati, E.; Tarrés-Call, J.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2022, 20, 4,
Abstract

The intestinal tract is a crucial part of the body for growth and development, and its dysregulation can cause several diseases. The lack of appropriate in vitro models hampers the development of effective preventions and treatments against these intestinal tract diseases. Intestinal organoids are...

Author(s)
Ma PanPan; Fang PuXian; Ren TianZe; Fang LiuRong; Xiao ShaoBo
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2022, 14, 5,
Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of ROVABIO® ADVANCE (liquid and solid) which contains endo-1,4-beta-xylanase and endo-1,3(4)-beta-glucanase. The enzymes present in the additive are produced by two strains of ...

Author(s)
Bampidis, V.; Azimonti, G.; Lourdes Bastos, M. de; Christensen, H.; Dusemund, B.; Durjava, M. F.; Kouba, M.; López-Alonso, M.; Puente, S. L.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Dierick, N.; Martelli, G.; Galobart, J.; Ortuño, J.; Anguita, M.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2022, 20, 5,
Abstract

OptiPhos® is the trade name of the feed additive under assessment containing 6-phytase produced by a genetically modified strain of Komagataella phaffii. It is authorised for use in chickens for fattening and reared for laying, turkeys for fattening and reared for breeding, other avian species for...

Author(s)
Bampidis, V.; Azimonti, G.; Lourdes Bastos, M. de; Christensen, H.; Dusemund, B.; Durjava, M. F.; Kouba, M.; López-Alonso, M.; Puente, S. L.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Galobart, J.; Anguita, M.; Ortuño, J.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2022, 20, 5,
Abstract

NADC30-like porcine reproductive and respiratory syndrome virus (PRRSV), which is highly homologous to the NADC30 strain isolated in the United States. The NADC30-like PRRSV was first reported in 2014 in China, where it spread and gradually caused an epidemic. Currently, growing research has shown...

Author(s)
Cao ZhengDa; Chen JinXia; Li LiWei; Liu JiaChen; Tong Wu; Zhou YanJun; Tong GuangZhi; Wang GuiHua; Gao Fei
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Virus Research, 2022, 316,
Abstract

RNA editing is an essential post-transcriptional regulatory mechanism. However, few studies have investigated the functional RNA edits in the economic traits of livestock on a genome-wide scale. Pigs are one of the most important livestock species and their fat is the principal organ involved in...

Author(s)
Zhang YueBo; Liu Xin; Zhang LongChao; Wang LiGang; He Jun; Ma HaiMing; Wang LiXian
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2022, 53, 3, pp 327-339

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