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News Article

Transgene-free method without monoclonal selection

Date
5 April 2022
News Article

Novel approach could help improve understanding of how infectious agents interact with the immune system of livestock and reduce the use of animals in research

Date
9 February 2022
Abstract

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 6-phytase (VTR-phytase) as zootechnical feed additive for all pigs and all avian species. The ...

Author(s)
Bampidis, V.; Azimonti, G.; Bastos, M. de L.; Christensen, H.; Dusemund, B.; Durjava, M. F.; Kouba, M.; López-Alonso, M.; Puente, S. L.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Aquilina, G.; Brantom, P.; Dierick, N.; Martelli, G.; Svensson, K.; Anguita, M.; Brozzi, R.; Galobart, J.; Casanova, J. O.; Pettenati, E.; Tarrés-Call, J.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2022, 20, 12,
Abstract

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of the product Huvezym® neXo 100 G/L containing an endo-1,4-beta xylanase, an...

Author(s)
Bampidis, V.; Azimonti, G.; Bastos, M. de L.; Christensen, H.; Dusemund, B.; Durjava, M. F.; Kouba, M.; López-Alonso, M.; Puente, S. L.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Aquilina, G.; Tosti, L.; Yurkov, A.; Anguita, M.; Galobart, J.; Ortuño, J.; Pizzo, F.; Tarrés-Call, J.; Pettenati, E.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2022, 20, 12,
Abstract

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the renewal of the authorisation of endo-1,4-β-xylanase produced by Trichoderma reesei CBS 143953 and...

Author(s)
Bampidis, V.; Azimonti, G.; Bastos, M. de L.; Christensen, H.; Dusemund, B.; Durjava, M. F.; Kouba, M.; López-Alonso, M.; Puente, S. L.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Galobart, J.; Pettenati, E.; Pizzo, F.; Revez, J.; Anguita, M.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2022, 20, 11,
Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 3-phytase produced by Komagataella phaffii (CECT 13171) (FSF10000/FLF1000) as a zootechnical additive for poultry species, pigs for fattening and minor porcine species. The ...

Author(s)
Bampidis, V.; Azimonti, G.; Bastos, M. de L.; Christensen, H.; Dusemund, B.; Durjava, M. F.; Kouba, M.; López-Alonso, M.; Puente, S. L.; Marcon, F.; Mayo, B.; Pechová, A.; Petkova, M.; Ramos, F.; Sanz, Y.; Villa, R. E.; Woutersen, R.; Dierick, N.; Martelli, G.; Pettenati, E.; Galobart, J.; Anguita, M.
Publisher
Wiley, Oxford, UK
Citation
EFSA Journal, 2022, 20, 11,
Abstract

A DNA fragment containing CpG motifs (CpG ODN) is one of the potent immunopotentiators used to improve vaccine efficacy. It can enhance a protective immunity by stimulating both innate and adaptive immune responses. In this study, we designed and constructed a recombinant plasmid carrying the...

Author(s)
Hansoongnern, P.; Phecharat, N.; Wasanasuk, K.; Tommeurd, W.; Chankeeree, P.; Lekcharoensuk, C.; Semkum, P.; Pinitkiatisakul, S.; Lekcharoensuk, P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2022, 275,
Abstract

Combining somatic cell nuclear transfer (SCNT) with genome editing technologies has emerged as a powerful platform for the creation of unique swine lineages for agricultural and biomedical applications. However, successful application of this research platform is still hampered by the low...

Author(s)
Macedo, M. P. de; Glanzner, W. G.; Gutierrez, K.; Currin, L.; Guay, V.; Herrera, M. E. C.; Silva, Z. da; Baldassarre, H.; McGraw, S.; Bordignon, V.
Publisher
MDPI AG, Basel, Switzerland
Citation
International Journal of Molecular Sciences, 2022, 23, 22,
Abstract

CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR-associated protein 9) technology is growing rapidly and has been greatly influencing the efficiency and effectiveness of genetic modifications in different applications. One aspect of research gaining importance in the...

Author(s)
Takebayashi, K.; Wittayarat, M.; Lin, Q.; Hirata, M.; Yoshimura, N.; Torigoe, N.; Nagahara, M.; Do, L. T. K.; Tanihara, F.; Otoi, T.
Publisher
Wiley, Berlin, Germany
Citation
Reproduction in Domestic Animals, 2022, 57, 10, pp 1136-1142
Abstract

Current studies on myostatin (MSTN), a well-known negative regulator of skeletal muscle, studies mainly focus on the its effects on skeletal muscle. However, its effects on smooth muscle are less studied, especially in the uterine horns. To identify the role of MSTN in uterine horn smooth muscle,...

Author(s)
Liu XinYue; Choe HakMyong; Li ZhouYan; Jin ZhengYun; Chang ShuangYan; Kang JinDan; Yin XiJun; Quan BiaoHu
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2022, 152, pp 228-235

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