An infectious disease emerged in recent years, Tilapia Lake Virus Disease (TiLVD), has severely restricted the development of global tilapia industry. Vaccination has proved potential strategy to prevent its causative agent Tilapia Lake Virus (TiLV) infectious. However, the response intensity of...

In poikilothermic animals like fish, outbreaks of pathogen-related diseases are closely related with the temperature of the surrounding environment. Many salmonid fish species are thermally sensitive and therefore are especially endangered by thermal stress and habitat loss caused by increasing...

Tilapia lake virus (TiLV) is highly contagious and pathogenic to tilapia, causing enormous economic losses in tilapia industry. Up to now, there is no commercial vaccine is available for against TiLV infection. Therefore, a novel vaccine with high immune efficacy is urgently-needed. In this study,...

A serological test for screening of TiLV in Oreochromis niloticus would be useful for the epidemiological investigations. Using polyclonal antisera against TiLV (TiLV-Ab), an indirect enzyme-linked immune sorbent assay (iELISA) was developed for the detection of TiLV antigen in fish tissue and...

Tilapia lake virus (TiLV) has recently been reported to cause infection in cultured and wild tilapia globally, and co-infection between TiLV and other bacterial pathogens contributes to higher mortality and economic losses. Understanding the pathology and pathogenesis of the co-infection could help ...

The emergence and spread of transboundary aquatic animal diseases have been frequently associated with international trade of live aquatic animals. Tilapia is one of the most traded aquatic animals and the recent global spread of Tilapia tilapinevirus, also known as tilapia lake virus (TiLV), is...

Tilapia tilapinevirus (or tilapia lake virus, TiLV) is a recently emerging virus associated with a novel disease affecting and decimating tilapia populations around the world. Since its initial identification, TiLV has been reported in 17 countries, often causing mortalities as high as 90% in the...

Tilapia lake virus (TiLV) is a novel RNA virus that has been causing substantial economic losses across the global tilapia industry. Despite extensive research on potential vaccines and disease control methods, the understanding of this viral infection and the associated host cell responses remains ...

To establish an assay of reverse transcription droplet digital PCR (RT-ddPCR) for Tilapia Lake Virus (TiLV), we designed a pair of specific primers and probe based on the conserved region of TiLV segment 3 and evaluated the specificity, sensitivity and repeatability of this method. The structured...

As an emerging pathogen, tilapia lake virus (TiLV) has caused severe socio-economic impacts and remains a devastating factor in wild and farmed tilapia. Early diagnosis and timely reporting of TiLV are very important and necessary. In the study, a TiLV infection event in a tilapia farm is studied...