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Abstract

Cholesterol 25-hydroxylase (CH25 H), as a host restriction factor, has been reported to take a broad-spectrum antiviral effect. However, the role of CH25H in Senecavirus A (SVA) infection remains unknown. In this study, we first demonstrate that overexpression of CH25H inhibits SVA replication....

Author(s)
Zhu HuiXin; Yan JunFang; Liu Xing; Li Liang; Liu WenWen; Wang XianWei; Jiang Ping; Bai Juan
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2021, 256,
Abstract

The objective of this study was to evaluate the efficacy of ultraviolet C light (UVC) for inactivating Senecavirus A (SVA) on three different experimentally contaminated surfaces commonly found in swine farms. An experimental study under controlled conditions assessed the effect of UVC on an SVA...

Author(s)
Ruston, C.; Zhang JianQiang; Scott, J.; Zhang Min; Graham, K.; Linhares, D.; Breuer, M.; Karriker, L.; Holtkamp, D.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2021, 256,
Abstract

To establish a rapid genotyping and quantitative detection method for the foot-and-mouth disease virus (FMDV), the rabbit anti-FMDV and guinea pig anti-FMDV antibodies were used for labeling colloidal gold and NC membrane with strips by double antibody sandwich method. And three types...

Author(s)
Li Xin; Sun YanYan; Lin Mi; Chen XiaHui; Li FengSong; Bao YanFang; Yang Guang; Jiang Tao
Publisher
Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China
Citation
Acta Veterinaria et Zootechnica Sinica, 2021, 52, 4, pp 1042-1052
AbstractFull Text

Senecavirus A (SVA), formerly known as Seneca valley virus (SVV) (20), is a critical pathogen causing vesicular lesions in pigs and acute death of newborn piglets, resulting in very large economic losses in the pig industry. The aim of this paper was to present the current knowledge about the...

Author(s)
Niedbalski, W.
Publisher
Polskie Towarzystwo Nauk Weterynaryjnych, Lublin, Poland
Citation
Medycyna Weterynaryjna, 2021, 77, 6, pp 273-278
Abstract

Extended feed storage to reduce the risk of virus survival has not been tested experimentally. Five ingredients inoculated with porcine epidemic diarrhea virus, porcine reproductive and respiratory syndrome virus-174, and Senecavirus A were stored indoors at 20°C or outdoors in Minnesota winter...

Author(s)
Dee, S.; Shah, A.; Cochrane, R.; Wu FangZhou; Clement, T.; Singrey, A.; Edler, R.; Spronk, G.; Niederwerder, M.; Nelson, E.
Publisher
American Association of Swine Veterinarians, Perry, USA
Citation
Journal of Swine Health and Production, 2021, 29, 3, pp 124-128
Abstract

Senecavirus A (SVA), an emerging swine pathogen, has been reported in many provinces of China since the first outbreak in 2015 in Guangdong province. In this study, 10 lymph nodes positive for SVA, collected between 2018 and 2019 from slaughterhouses in Guangdong province, were subjected to virus...

Author(s)
Jiang JianFeng; Zha YunFeng; Liu Jie; Xing ChaoNan; Mi ShiJiang; Yu JinXin; Sun YanWei; Tu ChangChun; Gong WenJie; Lu ZongJi
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Infection, Genetics and Evolution, 2021, 91,
Abstract

Senecavirus A (SVA) is an emerging picornavirus that has been associated with vesicular disease and neonatal mortality in swine. The construction of SVA virus carrying foreign reporter gene provides a powerful tool in virus research. However, it is often fraught with rescuing a recombinant...

Author(s)
Wang MinMin; Mou ChunXiao; Chen Mi; Chen ZhenHai
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Applied Microbiology and Biotechnology, 2021, 105, 6, pp 2385-2397
Abstract

This study aimed to analyze genomic properties and evolution of a Senecavirus A (SVA) strain CH-HNCY-2019. Eight pairs of primers were designed based on the genome sequence of SVV-001 (GenBank No. NC011349) and fragments covering the whole genome of strain CH-HNCY-2019 were amplified by RT-PCR. The ...

Author(s)
Li Ning; Guo HuiFang; Wang BaiYu; Qiao QiLong; Huang Qing; Li YongTao; Wang Zeng; Zhao Jun
Publisher
Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China
Citation
Acta Veterinaria et Zootechnica Sinica, 2021, 52, 2, pp 553-559
Abstract

Senecavirus A (SVA) is classified into the genus Senecavirus in the family Picornaviridae. Its genome is a positive-sense, single-stranded and nonsegmented RNA, approximately 7300 nucleotides in length. A picornaviral genome is essentially an mRNA, which, albeit unmodified with 5' cap structure,...

Author(s)
Liu FuXiao; Wang Ning; Huang YiLan; Wang QianQian; Shan Hu
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2021, 255,
Abstract

Objective: This study established an indirect ELISA method based on VP3 protein for detection of antibody to senecavirus A (SVA) in serum to provide an effective method for SVA infection in clinical pig population and evaluation of future vaccine immune. Method: The VP3 gene of SVA was cloned into...

Author(s)
Shen ShuiYing; Yan RuoQian; Lei CongCong; Wang ShuJuan; Ma ZhenYuan; Liu Ying; Zhao XueLi; Xie CaiHua; Wu ZhiMing
Publisher
Northwest A & F University (Natural Science Edition), Xianyang, China
Citation
Journal of Northwest A & F University - Natural Science Edition, 2021, 49, 2, pp 23-30

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