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Abstract

As an emergent picornavirus pathogenic to pigs, Senecavirus A (SVA) can replicate in pig kidneys and proliferates well in porcine kidney epithelial PK-15 cells. Here, tandem mass tags (TMT) labeling coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used to analyze the...

Author(s)
Gao Hang; Xiang ZhaoYing; Ge XinNa; Zhou Lei; Han Jun; Guo Xin; Chen YanHong; Zhang Yongning; Yang Hanchun
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2022, 14, 5,
Abstract

Synonymous codon bias in the viral genome affects protein translation and gene expression, suggesting that the synonymous codon mutant plays an essential role in influencing virulence and evolution. However, how the recessive mutant form contributes to virus evolvability remains elusive. In this...

Author(s)
Zhao SiMiao; Cui HuiQi; Hu ZhenRu; Du Li; Ran XuHua; Wen XiaoBo
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2022, 14, 5,
Abstract

Phosphorylation is a widespread posttranslational modification that regulates numerous biological processes. Viruses can alter the physiological activities of host cells to promote virus particle replication, and manipulating phosphorylation is one of the mechanisms. Senecavirus A (SVA) is the...

Author(s)
Li JieYi; Zhang ZhongWang; Lv JianLiang; Ma ZhongYuan; Pan Li; Zhang YongGuang
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Microbiology, 2022, 13, January,
Abstract

To investigate whether hnRNP M is involved in Senecavirus A(SVA) replication and infection, the recombinant plasmid PCAGGS-HA-hnRNP M was constructed in this study. After transfection into BHK-21 cells, the recombinant plasmid was detected by western blot, and the results showed that hnRNP M...

Author(s)
Cao ZhiYuan; Wei DanDan; Wang HaiWei; Sun Chao; Yu Li
Publisher
Chinese Journal of Preventive Veterinary Medicine, Harbin, China
Citation
Zhongguo Yufang Shouyi Xuebao / Chinese Journal of Preventive Veterinary Medicine, 2022, 44, 3, pp 263-268, 283
Abstract

In recent years, Seneca Valley virus (SVV) as a newly identified pathogen of porcine vesicular disease spread quickly and has posed a potential threat to the swine industry in several countries resulting in economic losses. Considering the evolution of SVV, attention should be given to controlling...

Author(s)
Zhang YuYuan; Sun MingXia; Lian YueXiao; Wang TongYun; Jia MeiYu; Leng ChaoLiang; Chen Meng; Bai YuanZhe; Meng FanDan; Cai XueHui; Tang YanDong
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Microbiology, 2022, 13, February,
Abstract

Vesicular disease caused by Seneca Valley virus (SVV) has recently emerged throughout China and caused certain industry losses. We used immunofluorescence and western blotting to confirm that 3 new SVV strains (CH-GDSG-2018-1, CH-GDSG-2018-2, and CH-GDSG-2018-3) were from 1 pig farm. Phylogenetic...

Author(s)
Dong JianGuo; Rao Dan; Geng Xin; Chen MingRui; He ShuHai; Jiao FengChao; Huang Li; Chen Bin; Zhao PanDeng; Cong Feng
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2022, 86, 2, pp 102-107
Abstract

Senecavirus A (SVA) has been demonstrated to be a causative agent for vesicular disease in swine. It is clinically indistinguishable from other agents that cause vesicular disease such as foot-and-mouth disease virus (FMDV), which is a reportable foreign animal disease (FAD). Thus, an investigation ...

Author(s)
Buckley, A. C.; Lager, K. M.
Publisher
American Association of Swine Veterinarians, Perry, USA
Citation
Journal of Swine Health and Production, 2022, 30, 3, pp 149-159
Abstract

Senecavirus A (SVA) infection in pigs causes vesicular disease and results in a short viremia and transient shedding of the virus, mainly in oral fluids and feces. Here we describe the consistent prolonged shedding of SVA in the semen of 2 boars, and persistence of SVA within the tonsils and testes ...

Author(s)
Sturos, M. J.; Murray, D.; Johnson, L.; Preis, G.; Corzo, C. A.; Rossow, S.; Vannucci, F. A.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Veterinary Diagnostic Investigation, 2022, 34, 3, pp 474-481
Abstract

Seneca Valley virus (SVV), also known as Senecavirus A (SVA), is a non-enveloped and single-strand positive-sense RNA virus, which belongs to the genus of Senecavirus within the family Picornaviridae. Porcine idiopathic vesicular disease (PIVD) caused by SVV has frequently been prevalent in America ...

Author(s)
Liu WenQiang; Li XiangMin; Zhang HuaWei; Hao Genxi; Shang XianFei; Wang HuiLan; Chen HuanChun; Qian Ping
Publisher
MDPI AG, Basel, Switzerland
Citation
Vaccines, 2022, 10, 4,
Abstract

Senecavirus a: (SVA), an emerging picornavirus, has been associated with vesicular disease and neonatal mortality in swine, posing a great threat to the global swine industry. Accurate diagnosis of SVA is crucial for the effective prevention and control disease. In the present study, a simple,...

Author(s)
Wang HuiBao; Dong JinJie; Zhang Tao; Wang Fan; Yang Rui; Zhang Yong; Zhao XingXu
Publisher
Elsevier Science, San Diego, USA
Citation
Analytical Biochemistry, 2022, 646,

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