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Abstract

The aim of this study was to characterize Mycobacterium bovis from cattle and buffalo tissue samples, from two Brazilian states, and to analyse their genetic diversity by spoligotyping. Tissue samples from tuberculosis suspect animals, 57 in Amazonas State (12 cattle and 45 buffaloes) and six from...

Author(s)
Carneiro, P. A. M.; Pasquatti, T. N.; Takatani, H.; Zumárraga, M. J.; Marfil, M. J.; Barnard, C.; Fitzgerald, S. D.; Abramovitch, R. B.; Araujo, F. R.; Kaneene, J. B.
Publisher
Wiley, Oxford, UK
Citation
Veterinary Medicine and Science, 2020, 6, 1, pp 133-141
Abstract

CpG motifs in DNA sequences are recognized by Toll-like receptor 9 and activate immune cells. Bacterial genomic DNA (gDNA) has modified cytosine bases (5-methylcytosine [5 mC]) and modified adenine bases (6-methyladenine [6 mA]). 5 mC inhibits immune activation by CpG DNA; however, it is unclear...

Author(s)
Tsukamoto, Y.; Tamura, T.; Maeda, Y.; Miyake, K.; Ato, M.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Tuberculosis, 2020, 121,
Abstract

Mycobacterium bovis is the cause of tuberculosis in most mammalian species, most notably cattle and other members of the family Bovidae; however, many species of the family Cervidae are also susceptible. In North America, tuberculosis has been identified in both captive and free-ranging cervids....

Author(s)
Palmer, M. V.; Waters, W. R.; Thacker, T. C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2020, 129, pp 70-73
Abstract

Although several countries have eradicated bovine tuberculosis, their fight has been challenging. There are several reasons for the residual infection in these sites and the transmission dynamics of Mycobacterium bovis is still poorly understood. Screening of the recent transmission and its...

Author(s)
Anzai, E. K.
Publisher
Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, Brazil
Citation
Sequenciamento do Genoma Completo do Mycobacterium bovis como instrumento de Sistema de Vigilância no Estado de Santa Catarina, 2019, pp 40 pp.
Abstract

A safe and effective adjuvant is necessary to induce reliable protective efficacy of the protein-based vaccines against tuberculosis (TB). Mycobacterial components, such as synthetic cord factor and arabinogalactan, have been used as one of the adjuvant components. Mycobacterium bovis bacillus...

Author(s)
Back YongWoo; Choi SeungA; Choi HanGyu; Shin KiWon; Son YeoJin; Paik TaeHyun; Kim HwaJung
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2019, 14, 3, pp e0213536
Abstract

In the absence of biomarkers of protective immunity, newly developed vaccines against bovine tuberculosis need to be evaluated in virulent Mycobacterium bovis challenge experiments, which require the use of expensive and highly in demand Biological Safety Level 3 (BSL3) animal facilities. The...

Author(s)
Biffar, L.; Blunt, L.; Atkins, W.; Anderson, P.; Holder, T.; Xing Zhou; Vordermeier, M.; McShane, H.; Villarreal-Ramos, B.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2020, 38, 5, pp 1241-1248
Abstract

Background: Wildlife poses a significant burden for the complete eradication of bovine tuberculosis (bTB). In particular, wild boar (Sus scrofa) is one of the most important reservoirs of Mycobacterium bovis, the causal agent of bTB. Wild boar can display from mild TB lesions, usually found in head ...

Author(s)
Bravo, M.; Combes, T.; Martinez, F. O.; Cerrato, R.; Rey, J.; Garcia-Jimenez, W.; Fernandez-Llario, P.; Risco, D.; Gutierrez-Merino, J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Microbiology, 2019, 10, July, pp 1663
CABI Book Info
Cover for Bovine tuberculosis.

This 269-paged book on Bovine Tubeculosis covers all aspects of Mycobacterium bovis biology and infection: epidemiological, pathological, microbiological, genomic and immunological together with a comparative approach to the different control schemes being undertaken in different countries. It has...

Author(s)
Chambers, M.; Gordon, S.; Olea-Popelka, F.; Barrow, P.
ISBN
2018 CAB International (H ISBN 9781786391520)
Type
Book
Abstract

Mycobacterium bovis is the pathogenic agent responsible for bovine tuberculosis (bTB), a zoonotic disease affecting mostly cattle, but also transmittable to humans and wildlife. Genetic studies on M. bovis allow to detect possible routes of bTB transmission and the identification of genetic...

Author(s)
Inlamea, O. F.; Soares, P.; Ikuta, C. Y.; Heinemann, M. B.; Achá, S. J.; Neto, J. S. F.; Correia-Neves, M.; Rito, T.; Machado, A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS Neglected Tropical Diseases, 2020, 14, 3,
Abstract

In South Africa, bovine tuberculosis threatens some of Africa's most iconic wildlife species, including the cheetah (Acinonyx jubatus). The lack of antemortem diagnostic tests for this species strongly hinders conservation efforts. We report use of antemortem and postmortem diagnostic assays to...

Author(s)
Kerr, T. J.; Gumbo, R.; Goosen, W. J.; Rogers, P.; Last, R. D.; Miller, M. A.
Publisher
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, USA
Citation
Emerging Infectious Diseases, 2020, 26, 3, pp 630-631

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