Background: The Dogo Argentino dog breed is affected by hereditary congenital sensorineural deafness (CSD) associated with white pigmentation, but prevalence data and associations with phenotypes have not been reported. Methods: In a retrospective study, animals were tested by the brainstem...
Publisher
Wiley, Chichester, UK
Citation
Veterinary Record, 2021, 188, 9,
Pigment-associated deafness is a common hereditary condition in a range of dog breeds. The aim of this study was to perform a genome-wide association analysis to investigate the genetic architecture of deafness in Australian Cattle Dogs. Genotypes for 104 757 polymorphisms in 216 dogs were...
Author(s)
Seddon, J. M.; Fortes, M.; Kelly-Smith, M.; Sommerlad, S. F.; Hayward, J. J.; Burmeister, L.; Risio, L. de; Mellersh, C.; Freeman, J.; Strain, G. M.
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2021, 52, 5, pp 694-702
OBJECTIVE: To assess the presence of suspected pigment-associated deafness in North American yaks (Bos grunniens). ANIMALS 12 North American yaks, including 11 with the homozygous piebald Royal pigmentation phenotype and 1 with the heterozygous piebald Trim phenotype. PROCEDURES: Hearing was...
Author(s)
Strain, G. M.; Hardy, T.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2022, 83, 10,
It is hypothesized that in the "more highly evolved" mammals, including the domesticated mammals, that the brainstem and the cerebellum receive arterial blood through the vertebrobasilar system whilst the internal carotid arteries primarily supply the forebrain. In camels, the arterial blood supply ...
Author(s)
Aiyan, A. A.; Menon, P.; Aldarwich, A.; Qablan, M.; Hammoud, M.; Shawaf, T.; Richardson, K.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2021, 7, June,
Most canine deafness is linked to white pigmentation caused by the piebald locus, shown to be the gene MITF (melanocyte inducing transcription factor), but studies have failed to identify a deafness cause. The coding regions of MITF have not been shown to be mutated in deaf dogs, leading us to...
Author(s)
Kelly-Smith, M.; Strain, G. M.
Publisher
Elsevier, Oxford, UK
Citation
Veterinary and Animal Science, 2020, 9,
Congenital deafness in the domestic dog is usually related to the presence of white pigmentation, which is controlled primarily by the piebald locus on chromosome 20 and also by merle on chromosome 10. Pigment-associated deafness is also seen in other species, including cats, mice, sheep, alpacas,...
Author(s)
Hayward, J. J.; Kelly-Smith, M.; Boyko, A. R.; Burmeister, L.; Risio, L. de; Mellersh, C.; Freeman, J.; Strain, G. M.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2020, 15, 5,
Recordings of distortion product otoacoustic emissions (DPOAEs) were taken from 15 geriatric cats (mean age±standard deviation, SD, 13.6±2.7 years; range 10.2-19.4 years) and 12 young adult control cats (mean±SD 4.6±0.5 years; range 3.4-5 years) to identify frequency-specific age-related changes in ...
Author(s)
Strain, G. M.; McGee, K. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2017, 221, pp 34-37
The objective of the study was to assess the neurotoxicity, using electrodiagnostic tests, of hydramethylnon (Amdro, AC 217,300), an insecticide marketed for the treatment of red imported fire ants, cockroaches, and other insects. Animals were male Fisher 344 albino rats and Long-Evans hooded rats. ...
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2019, 124, pp 452-460
Current descriptions of the anatomy of the blood supply to the canine middle ear are either incomplete or inconsistent, particularly in regards to the vascular branches in close proximity to the temporomandibular articulation (TMJ). To further investigate this blood supply, dissections (n=9),...
Author(s)
Stevens-Sparks, C.; Jarrett, K., III; McNulty, M. A.; Strain, G. M.
Publisher
Wiley-Blackwell, Hoboken, USA
Citation
Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology, 2016, 299, 7, pp 907-917
Recordings of distortion product otoacoustic emissions (DPOAE) were taken from 28 geriatric dogs aged 12.2±2.2 years and 15 control dogs aged 5.9±3.0 years (mean±standard deviation) to demonstrate frequency-specific changes in cochlear responses. Recordings were performed for primary frequencies of ...
Author(s)
Strain, G. M.; Martinez, A. J. R.; McGee, K. A.; McMillan, C. L.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Journal, 2016, 216, pp 101-106