OBJECTIVE: To determine whether palmar digital nerve (PDN) blockade in horses with a combination of dexmedetomidine and mepivacaine would block the response to mechanical force applied to the digit longer than would anesthetizing these nerves with mepivacaine alone or dexmedetomidine alone....
Author(s)
Nichols, C. L.; Doherty, T. J.; Schumacher, J.; Jones, P. D.; Sun XiaoCun
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2022, 83, 2, pp 114-118
Objective: To determine the effect of a novel scaffold, designed for use in bone regeneration, on healing of splint bone segmental defects in mares. Study design: In vivo experimental study. Sample population: Five adult mares (4-10 years old; mean weight, 437.7 kg ± 29 kg). Methods: Bilateral 2-cm ...
Author(s)
Grzeskowiak, R. M.; Alghazali, K. M.; Hecht, S.; Donnell, R. L.; Doherty, T. J.; Smith, C. K.; Anderson, D. E.; Biris, A. S.; Adair, H. S.
Publisher
Wiley, Boston, USA
Citation
Veterinary Surgery, 2021, 50, 5, pp 1117-1127
OBJECTIVE: To determine the efficacy and duration of effect for liposomal bupivacaine following perineural administration to the medial and lateral palmar digital nerves of horses. ANIMALS: 9 nonlame mares. PROCEDURES: For each horse, 2 mL of liposomal bupivacaine (13.3 mg/mL; total dose, 53.2 mg...
Author(s)
McCracken, M. J.; Schumacher, J.; Doherty, T. J.; Sun XiaoCun; Nichols, C. L.; Olivarez, J.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2020, 81, 5, pp 400-405
The objectives of this study were to determine the sedative effects and pharmacokinetic profile of detomidine when administered intravaginally as a gel formulation to horses. Six adult mares were administered either detomidine hydrochloride intravenously or detomidine gel intravaginally (treatment...
Author(s)
Seddighi, R.; Knych, H. K.; Cox, S. K.; Sun, X.; Moorhead, K.; Doherty, T. J.
Publisher
American Association of Equine Practitioners (AAEP), Lexington, USA
Citation
Proceedings of the 65th Annual Convention of the American Association of Equine Practitioners, Denver, Colorado, USA, 7-11 December 2019, 2019, pp 66-66
Objective: To determine the effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone required to prevent movement in response to a noxious stimulus (MIRNM) in dogs. Study design: Experimental crossover design. Animals: A group of six healthy, adult, intact female mixed-breed ...
Author(s)
Bennett, K. J.; Seddighi, R.; Moorhead, K. A.; Messenger, K.; Cox, S. K.; Sun XiaoCun; Pasloske, K.; Pypendop, B. H.; Doherty, T. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 2, pp 173-181
Objectives: To evaluate the sedative effects and pharmacokinetics of detomidine gel administered intravaginally to alpacas in comparison with intravenously (IV) administered detomidine. Study design: Randomized, crossover, blinded experiment. Animals: A group of six healthy adult female Huacaya...
Author(s)
Chow, N. S.; Seddighi, R.; Knych, H. K.; Sun XiaCun; Doherty, T. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 6, pp 773-780
OBJECTIVE: To determine effects of fentanyl, lidocaine, and a fentanyl-lidocaine combination on the minimum alveolar concentration of sevoflurane preventing motor movement (MACNM) in dogs. ANIMALS: 6 adult Beagles. PROCEDURES: Dogs were anesthetized with sevoflurane in oxygen 3 times (1-week...
Author(s)
Suarez, M. A.; Seddighi, R.; Egger, C. M.; Rohrbach, B. W.; Cox, S. K.; KuKanich, B. K.; Doherty, T. J.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 1, pp 12-16
OBJECTIVE: To evaluate agreement among diplomates of the American College of Veterinary Anesthesia and Analgesia for scores determined by use of a simple descriptive scale (SDS) or a composite grading scale (CGS) for quality of recovery of horses from anesthesia and to investigate use of 3-axis...
Author(s)
Clark-Price, S. C.; Lascola, K. M.; Carter, J. E.; Cunha, A. F. da; Donaldson, L. L.; Doherty, T. J.; Martin-Flores, M.; Hofmeister, E. H.; Keating, S. C. J.; Mama, K. R.; Mason, D. E.; Posner, L. P.; Sano, H.; Seddighi, R.; Shih, A. C.; Weil, A. B.; Schaeffer, D. J.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 6, pp 668-676
Objective: To determine the effect of dexmedetomidine on induction dose and minimum infusion rate of propofol preventing movement (MIRNM). Study design: Randomized crossover, unmasked, experimental design. Animals: Three male and three female healthy Beagle dogs weighing 10.2±2.8 kg. Methods: Dogs...
Author(s)
Smith, C. K.; Seddighi, R.; Cox, S. K.; Sun XiaoCun; Knych, H. K.; Doherty, T. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2017, 44, 6, pp 1287-1295
Objective: To determine the effect of fentanyl on the induction dose of propofol and minimum infusion rate required to prevent movement in response to noxious stimulation (MIRNM) in dogs. Study design: Crossover experimental design. Animals: Six healthy, adult intact male Beagle dogs, mean±standard ...
Author(s)
Davis, C. A.; Seddighi, R.; Cox, S. K.; Sun XiaoCun; Egger, C. M.; Doherty, T. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2017, 44, 4, pp 727-737