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Besnoitiosis in donkeys in the UK


First report of Besnoitia bennetti infection in donkeys in the UK

A study published in Parasites and Vectors reports a series of cases of besnoitiosis in donkeys from the Donkey Sanctuary in England, UK.

Equine besnoitiosis is a disease that occurs in donkeys, horses, zebras and mules. Donkeys with besnoitiosis develop multiple parasitic cysts on the skin, over the nostrils, ears and face.

One of the most unique features of besnoitiosis is the development of tiny cysts on the surface of the eye. Some infected animals remain otherwise healthy, while others become thin and debilitated as a result of the disease.

Previously, the parasitic disease was a rarely detected condition in most countries, including in the US, Spain, Belgium, and Italy. Although the clinical signs associated with besnoitiosis were not seen in the UK cases, this study has important clinical relevance.

Besnoitiosis was initially discovered UK in 2013, when a donkey at the Donkey Sanctuary was presented with skin lumps that were presumed to be sarcoid tumours. Microscopic examination of the affected skin tissue of the donkey revealed the presence of cysts similar to those caused by Besnoitia bennetti, alongside the finding of tissue changes associated with a sarcoid.

This case triggered a collaboration between a team of clinicians from the Donkey Sanctuary and a veterinary parasitologist from the School of Veterinary Medicine and Science at the University of Nottingham, of this emerging parasitic infection. Since then upwards of 20 clinical cases have been identified and studied.

Dr Rebekah Sullivan, co-author of the report and a vet at the Donkey Sanctuary, said, “Given the relative proximity to other European countries, where clinical besnoitiosis is apparent, our findings will inform British vets of the potential for this emerging disease so that they can better recognise the pattern of clinical signs during clinical examination.”

“It is absolutely essential – particularly now – that vets in the UK learn more about besnoitiosis, so they can identify and protect donkeys potentially at risk. Knowledge obtained in this study should improve our response to this emerging parasitic disease in donkeys in the UK, especially with the few treatment options and the unknown routes of transmission,” said Dr Hany Elsheikha, lead author of the study and Associate Professor of Parasitology at the University of Nottingham.

Several serological methods and screening strategies have been developed to help guide veterinarians to earlier diagnosis and treatment of the disease.

Gereon Schares from the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Germany, and co-author of the report, said, “This study is particularly important because by using a suite of molecular methods we were able to confirm for the first time in Europe that the parasite agent involved in these cases is specifically Besnoitia bennetti and infection can be shown by serological methods.”

The correct identification of Besnoitia cysts in skin biopsies taken from UK donkeys does have clinical advantage for veterinarians providing a more accurate prognoses where a skin mass has been identified.

“It can no longer be assumed that skin masses are either neoplastic in origin or inflammatory, such as eosinophilic granulomas, for example,” said George Paraschou, co-author and pathologist at the Donkey Sanctuary.

Article: Elsheikha, H.M., Schares, G., Paraschou, G., Sullivan, R., Fox, R. (2020). First record of besnoitiosis caused by Besnoitia bennetti in donkeys from the UK. Parasites & Vectors 13, 279, doi: 10.1186/s13071-020-04145-8

Article details

  • Date
  • 10 June 2020
  • Source
  • University of Nottingham
  • Subject(s)
  • Horses and other Equines