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Abstract

Human tuberculosis remains a significant cause of mortality and morbidity throughout the world. The global economic impact of bovine TB is considerable. An effective vaccine would be the most cost-effective way to control both epidemics, particularly in emerging economies. TB vaccine research would ...

Author(s)
Pepponi, I.; Khatri, B.; Tanner, R.; Villarreal-Ramos, B.; Vordermeier, M.; McShane, H.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Tuberculosis, 2017, 106, pp 118-122
Abstract

Bovine tuberculosis is a zoonotic disease of global public health concern. Development of diagnostic tools to improve test accuracy and efficiency in domestic livestock and enable surveillance of wildlife reservoirs would improve disease management and eradication efforts. Use of volatile organic...

Author(s)
Ellis, C. K.; Rice, S.; Maurer, D.; Stahl, R.; Waters, W. R.; Palmer, M. V.; Nol, P.; Rhyan, J. C.; VerCauteren, K. C.; Koziel, J. A.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2017, 12, 7, pp e0179914
Abstract

Because biological systems are complex, management interventions occasionally have unintended adverse consequences. For example, attempts to control bovine tuberculosis (TB) by culling badgers Meles meles have, under some circumstances, inadvertently increased cattle TB risks. Such harmful effects...

Author(s)
Woodroffe, R.; Donnelly, C. A.; Ham, C.; Jackson, S. Y. B.; Moyes, K.; Chapman, K.; Stratton, N. G.; Cartwright, S. J.
Publisher
Wiley, Oxford, UK
Citation
Journal of Applied Ecology, 2017, 54, 3, pp 718-725
Abstract

Currently, the BCG vaccine is used to prevent tuberculosis, but the immune effect is not ideal due to varied reasons. The existence of drug-resistant strains of tuberculosis and the increased prevalence and incidence of AIDS have lead to the increased incidence of tuberculosis year by year....

Author(s)
Chen JingRui; Zhou BuDan; Liu Lei; Jiang XiuYun
Publisher
Chinese Journal of Zoonoses, Fuzhou, China
Citation
Chinese Journal of Zoonoses, 2017, 33, 1, pp 67-71
Abstract

The oral vaccination of wild badgers (Meles meles) with live Bacillus Calmette-Guérin (BCG) is one of the tools being considered for the control of bovine tuberculosis (caused by Mycobacterium bovis) in the UK. The design of a product for oral vaccination requires that numerous, and often...

Author(s)
Gowtage, S.; Williams, G. A.; Henderson, R.; Aylett, P.; MacMorran, D.; Palmer, S.; Robertson, A.; Lesellier, S.; Carter, S. P.; Chambers, M. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2017, 35, 6, pp 987-992
Abstract

Tuberculosis (TB) remains a serious global health threat and an improved vaccine is urgently needed. New candidate TB vaccines are tested using preclinical animal models such as mice, guinea pigs, cattle and non-human primates. Animals are routinely infected with virulent Mycobacterium tuberculosis ...

Author(s)
Tanner, R.; McShane, H.
Publisher
Society ALTEX Edition, Kuesnacht, Switzerland
Citation
ALTEX: Alternatives to Animal Experimentation, 2017, 34, 1, pp 157-166
AbstractFull Text

The Brazilian Ministry of Agriculture, Livestock and Food Supply established the National Program for Control and Eradication of Brucellosis and Tuberculosis (PNCEBT) in 2001. One of the main strategies adopted by the program is the mandatory vaccination of heifers between three and eight months of ...

Author(s)
Souza, V. A. F. de; Ferreira Neto, J. S.; Amaku, M.; Dias, R. A.; Telles, E. O.; Grisi Filho, J. H. H.; Heinemann, M. B.; Ferreira, F.
Publisher
Universidade Estadual de Londrina, Londrina, Brazil
Citation
Semina: Ciências Agrárias (Londrina), 2016, 37, 5, Suppl. 2, pp 3767-3775
AbstractFull Text

In light of recent efforts in Brazil to increase B19 strain vaccine coverage of heifers, this study proposes a standardized methodology for the calculation of vaccination coverage among the Federal Units. To illustrate its use, the method was applied to data from the state of Mato Grosso to...

Author(s)
Kuroda, R. B. dos S.; Negreiros, R. L.; Ossada, R.; Ferreira Neto, J. S.; Amaku, M.; Dias, R. A.; Telles, E. O.; Grisi Filho, J. H. H.; Heinemann, M. B.; Ferreira, F.
Publisher
Universidade Estadual de Londrina, Londrina, Brazil
Citation
Semina: Ciências Agrárias (Londrina), 2016, 37, 5, Suppl. 2, pp 3759-3766
Abstract

In the UK and the Republic of Ireland, the European badger (Meles meles) is a maintenance host for Mycobacterium bovis, and may transmit the infection to cattle causing bovine tuberculosis (TB). Vaccination of badgers using an injectable Bacillus Calmette-Guerin (BCG) vaccine is undertaken in some...

Author(s)
Robertson, A.; Delahay, R. J.; McDonald, R. A.; Aylett, P.; Henderson, R.; Gowtage, S.; Chambers, M. A.; Carter, S. P.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2016, 135, pp 95-101
Abstract

In this study we investigated whether oral uptake of a heat inactivated M. bovis wildlife vaccine by domestic cattle induced systemic immune responses that compromised the use of tuberculin or defined antigens in diagnostic tests for bovine TB. Positive skin test and blood-based IFN-γ release assay ...

Author(s)
Jones, G. J.; Steinbach, S.; Sevilla, I. A.; Garrido, J. M.; Juste, R.; Vordermeier, H. M.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2016, 182, pp 85-88

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