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News Article

Study of canine mitral valve disease and congestive heart failure provides clues to target therapies in dogs and human mitral valve prolapse.

Date
18 July 2017
Abstract

Background: Biologic variability (BV) is one aspect of interpreting changes in biomarker concentrations known to be clinically important in people with cardiac disease, but it has not been adequately addressed in dogs so far. Objectives: The purpose of the study was to determine BV of cardiac...

Author(s)
Winter, R. L.; Saunders, A. B.; Gordon, S. G.; Miller, M. W.; Fosgate, G. T.; Suchodolski, J. S.; Steiner, J. M.
Publisher
Wiley, Boston, USA
Citation
Veterinary Clinical Pathology, 2017, 46, 2, pp 299-307
Abstract

Background: The median age at presentation for dogs with patent ductus arteriosus (PDA) is <6 months of age, and closure is associated with a decrease in heart size and increased survival time, which are not well described in older dogs. Objectives: To describe the clinical characteristics of dogs with PDA ≥5 years of age at the time of presentation to a veterinary referral hospital. Animals: 35 client-owned dogs. Methods: Retrospective ...

Author(s)
Boutet, B. G.; Saunders, A. B.; Gordon, S. G.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 3, pp 685-690
Abstract

Background: The assessment of left atrial (LA) function by 2-dimensional speckle tracking echocardiography (STE) holds important clinical implications in human medicine. Few similar data are available in dogs. Objectives: To assess LA function by STE in dogs with and without myxomatous mitral valve ...

Author(s)
Toaldo, M. B.; Romito, G.; Guglielmini, C.; Diana, A.; Pelle, N. G.; Contiero, B.; Cipone, M.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 3, pp 641-649
Abstract

Objectives: To evaluate tricuspid annular plane systolic excursion (TAPSE) in dogs with myxomatous mitral valve disease (MMVD) with or without pulmonary hypertension (PH) and to study the correlations with clinical and echocardiographic parameters. Animals: The study population included 99 dogs...

Author(s)
Poser, H.; Berlanda, M.; Monacolli, M.; Contiero, B.; Coltro, A.; Guglielmini, C.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Veterinary Cardiology, 2017, 19, 3, pp 228-239
Abstract

Introduction: Aldosterone breakthrough (ABT) is the condition in which angiotensin converting enzyme inhibitors (ACEIs) and/or angiotensin receptor blockers fail to effectively suppress the activity of the renin angiotensin aldosterone system. The objective of this study was to determine if ABT...

Author(s)
Ames, M. K.; Atkins, C. E.; Eriksson, A.; Hess, A. M.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Veterinary Cardiology, 2017, 19, 3, pp 218-227
Abstract

Introduction: An important aspect of heart failure is the progressive ineffectiveness of the salutary natriuretic peptide system and its secondary messenger, 3′,5′-cyclic guanosine monophosphate (cGMP). In humans with acute heart failure, administration of exogenous natriuretic peptide is...

Author(s)
Oyama, M. A.; Solter, P. F.; Thorn, C. L.; Stern, J. A.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Journal of Veterinary Cardiology, 2017, 19, 3, pp 211-217
Abstract

An 11-year-old intact male Shih Tzu dog was referred to the University Veterinary Hospital (UVH) with history of coughing and laboured breathing. Auscultation revealed that the dog had a left systolic heart murmur grade V/VI at the base of the heart. Radiography showed findings of cardiomegaly and...

Author(s)
Teoh, Y. B.; Khor, K. H.
Publisher
Veterinary Association of Malaysia, UPM, Serdang, Malaysia
Citation
Jurnal Veterinar Malaysia, 2017, 29, 1, pp 18-22
Abstract

Author(s)
Rishniw, M.
Publisher
Elsevier Inc., Philadelphia, USA
Citation
Advances in Small Animal Medicine and Surgery, 2017, 30, 4, pp 1-3
Abstract

The clinical signs and diagnosis of mitral valve disease in a 15-year-old dog in France [date no given] are presented.

Author(s)
Serres, F.
Publisher
Newsmed, Paris, France
Citation
Point Vétérinaire, 2017, 48, 377(Part 1), pp 59

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