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CABI Animal Welfare Symposium - 'The Human Animal Bond' 21 June 2017, Royal Veterinary College, London, UK

CABI Animal Welfare Symposium - 'Animals Behaving Badly' 27 June 2017, UC Davis, California, USA

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Abstract

Mild to moderate equine asthma (EA) is the newly adopted term which defines the syndrome previously known as inflammatory airway disease (IAD). The adoption of this new nomenclature recognises the clinical phenotypic overlap amongst various non-infectious diseases of the equine lower airways; most...

Author(s)
Pirie, R. S.
Publisher
MA Healthcare Limited, London, UK
Citation
Livestock, 2017, 22, 3, pp 158-163
Abstract

OBJECTIVE: To develop a method to maintain the initial phenotype of airway smooth muscle (ASM) cells isolated from equine endobronchial biopsy specimens in long-term cell culture. SAMPLE: Endobronchial tissue specimens (8 to 10/horse) collected from the lungs of previously healthy horses at...

Author(s)
Vargas, A.; Peltier, A.; Dubé, J.; Lefebvre-Lavoie, J.; Moulin, V.; Goulet, F.; Lavoie, J. P.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 3, pp 359-370
Abstract

OBJECTIVE: To evaluate the influence of respiratory tract disease (ie, recurrent airway obstruction [RAO]) and mode of inhalation on detectability of inhaled budesonide in equine plasma and urine samples. ANIMALS: 16 horses (8 healthy control horses and 8 horses affected by RAO, as determined by...

Author(s)
Barton, A. K.; Schenk, H. H. I.; Machnik, M.; Gehlen, H.
Publisher
American Veterinary Medical Association, Schaumburg, USA
Citation
American Journal of Veterinary Research, 2017, 78, 2, pp 244-250
Abstract

Neutrophils participate in innate immunity as the first line of host defense against microorganisms. However, exacerbated neutrophil activity can be harmful to surrounding tissues; this is important in a range of diseases, including allergic asthma and chronic obstructive pulmonary disease in...

Author(s)
Borlone, C.; Morales, N.; Henriquez, C.; Folch, H.; Olave, C.; Sarmiento, J.; Uberti, B.; Moran, G.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2017, 110, pp 60-64
Abstract

This paper reports on the results of a study that investigates on the results of using bronchoprovocation tests in confirming if coughing is always associated with diseases of the respiratory tract. The result of the study confirmed the association of cough in cases of lung diseases such as asthma.

Author(s)
Durand, É.
Publisher
NÉVA Europarc, Créteil, France
Citation
Le Nouveau Praticien Vétérinaire - Équine, 2016, 11, 40, pp 49-50
Abstract

The aim of this study was to compare results of four different allergy tests from healthy and RAO-affected horses and to evaluate the clinical relevance of positive tested allergens via specific inhalation provocation test. Nine RAO-affected horses and 6 healthy horses underwent a complete lung...

Author(s)
Lindner, D.
Publisher
Freien Universität Berlin, Berlin, Germany
Citation
Inhalationsprovokationstest mit spezifischen Allergenen bei Pferden mit "Recurrent Airway Obstruction" (RAO), 2016, pp 128 pp.
Abstract

Equine inflammatory airway disease (IAD) and recurrent airway obstruction (RAO) represent a spectrum of chronic inflammatory disease of the airways in horses resembling human asthma in many aspects. Therefore, both are now described as severity grades of equine asthma. Increasing evidence in horses ...

Author(s)
Barton, A. K.; Gehlen, H.
Publisher
Hindawi Publishing Corporation, New York, USA
Citation
Mediators of Inflammation, 2016, 2016, pp Article ID 5693205
AbstractFull Text

Recurrent airway obstruction (RAO) represents a serious health problem and is traditionally classified as an allergic disease, where contact with an antigen can induce clinical airway inflammation, bronchial hyper-responsiveness and reversible airway obstruction. Previous studies have demonstrated...

Author(s)
Niedzacute˜wiedzacute˜, A.; Borowicz, H.; Kubiak, K.; Nicpoń, J.; Skrzypczak, P.; Jaworski, Z.; Cegielski, M.; Nicpoń, J.
Publisher
Polish Academy of Sciences, Committee of Veterinary Sciences, Olsztyn-Kortowo II, Poland
Citation
Polish Journal of Veterinary Sciences, 2016, 19, 4, pp 785-791
Abstract

Background: Overexpression of matrix-metalloproteinases (MMPs) has been shown to lead to tissue damage in equine recurrent airway obstruction (RAO), as a misbalance with their natural inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), occurs. This favors irreversible pulmonary...

Author(s)
Barton, A. K.; Shety, T.; Bondzio, A.; Einspanier, R.; Gehlen, H.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2016, 12, 282, pp (9 December 2016)
Abstract

Background: Procalcitonin (PCT), a precursor protein of the hormone calcitonin, is a sensitive inflammatory marker in human medicine, which is primarily used for diagnosis of bacterial sepsis, but is also useful in diagnosis of exacerbation of asthma and COPD. In this study, PCT was evaluated as a...

Author(s)
Barton, A. K.; Pelli, A.; Rieger, M.; Gehlen, H.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2016, 12, 281, pp (9 December 2016)

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