The rising problem of resistance to most commonly used antimalarials remains a major challenge in the control of malaria suggesting the need for new antimalarial agents. This work explores the antiplasmodial potential of ethanol extract of Russelia equisetiformis in chloroquine Plasmodium berghei...
Author(s)
Ojurongbe, O.; Ojo, J. A.; Adefokun, D. I.; Abiodun, O. O.; Odewale, G.; Awe, E. O.
Publisher
Medknow Publications, Mumbai, India
Citation
Indian Journal of Pharmaceutical Sciences, 2015, 77, 4, pp 504-510
Extracts from the leaf of Tithonia diversifolia used in folk medicine for treatment of various ailments were tested for antimalaria and mosquito repellency properties in experimental animals and human volunteers, under the laboratory conditions. Comparison of the effectiveness of Chloroquine with...
Author(s)
Oyewole, I. O.; Ibidapo, C. A.; Moronkola, D. O.; Oduola, A. O.; Adeoye, G. O.; Anyasor, G. N.; Obansa, J. A.
Publisher
Academic Journals, Nairobi, Kenya
Citation
Journal of Medicinal Plants Research, 2008, 2, 8, pp 171-175
Twenty extracts, 10 EtOH and 10 CH2Cl2, from different parts of 9 African medicinal plants used in Congolese traditional medicine for the treatment of malaria, were submitted to a pharmacological test in order to evaluate their effect on Plasmodium falciparum growth in vitro. Of these plant...
Author(s)
Tona, L.; Ngimbi, N. P.; Tsakala, M.; Mesia, K.; Cimanga, K.; Apers, S.; Bruyne, T. de; Pieters, L.; Totté, J.; Vlietinck, A. J.
Citation
Journal of Ethnopharmacology, 1999, 68, 1/3, pp 193-203
Antimalarial principles of an extract of stem bark of S. campanulata were isolated and characterized as 3β-hydroxyurs-12-en-28-oic acid (ursolic acid) and 2 of its derivatives: 3β-hydroxyurs-12,19-dien-28-oic acid (tomentosolic acid) and 3β,20β-dihydroxyurs-12-en-28-oic acid. The 3 compounds...
Author(s)
Amusan, O. O. G.; Adesogan, E. K.; Makinde, J. M.
Citation
Phytotherapy Research, 1996, 10, 8, pp 692-693
Malarial 5 is a traditional Mali drug composed of Cassia occidentalis leaves, Lippia chevalieri plants and Spilanthes oleracea flower heads, administered as a decoration. The preparation and its individual components were used in an in vitro experiment with Plasmodium falciparum and an in vivo...
Author(s)
Gasquet, M.; Delmas, F.; Timon-David, P.; Keita, A.; Guindo, M.; Koita, N.; Diallo, D.; Doumbo, O.
Citation
Fitoterapia, 1993, 64, 5, pp 423-426
Bark aqueous extracts of Kaya [Khaya] grandifoliola, K. ivorensis and K. senegalensis were applied orally at 12.5-50 mg/kg daily to mice inoculated with Plasmodium berghei berghei. The results of both a 4-day test for immediate activity and a test for residual activity showed that K. ivorensis was...
Author(s)
Awe, S. O.; Makinde, J. M.
Citation
Fitoterapia, 1991, 62, 6, pp 467-473
A total of 148 Brazilian plants, mostly in the form of crude extracts, from 38 families, were tested for antimalarial activity against Plasmodium berghei in mice. All were inactive at 100 mg/kg (4 oral doses), including one isolated from Ampelozizythus amazonicus (Rhamnaceae), known in Amazonian...
Author(s)
Brandão, M. das G. L.; Botelho, M. da G. A.; Krettli, E. A. U.
Citation
Ciência e Cultura, 1985, 37, 7, pp 1152-1163