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CABI Book Chapter

Environmental risk assessment of genetically modified organisms, Volume 3. Methodologies for transgenic fish.

Book cover for Environmental risk assessment of genetically modified organisms, Volume 3. Methodologies for transgenic fish.


This book on methodologies for risk assessment and management of transgenic fish is written by 44 authors from 19 countries. It is comprised of 10 chapters giving emphasis on developing countries which have transgenic fish research programmes or aquaculture systems that may use transgenic fish in the future. This book is aimed at helping governments, scientists, potential users of genetically modi...

Chapter 5 (Page no: 112)

Approaches to assessing gene flow.

This chapter focuses on ways to assess the likelihood of gene flow before approved use and actual entry of transgenic fish into the environment. A step-by-step approach for assessing gene flow based on a fault tree of the chain of events necessary for introgression of transgenes into a wild population is presented. Partition entry and introgression into subcomponents are discussed. The importance of assessing how both the transgene and overall genetic background of the escaping transgenic fish may affect the likelihood and consequences of gene flow to wild relatives is addressed. The main data needed for assessing gene flow are identified. Moreover, possible modelling, field and laboratory studies to obtain the data needed are described.

Other chapters from this book

Chapter: 1 (Page no: 1) Introduction to environmental risk assessment for transgenic fish. Author(s): Hayes, K. R. Kapuscinski, A. R. Dana, G. Li, S. Devlin, R. H.
Chapter: 2 (Page no: 29) Problem formulation and options assessment: science-guided deliberation in environmental risk assessment of transgenic fish. Author(s): Nelson, K. C. Basiao, Z. Cooper, A. M. Dey, M. Fonticiella, D. Lorenzo Hernandez, M. Kunawasen, S. Leelapatra, W. Li, S. Ratner, B. D. Toledo, M. I.
Chapter: 3 (Page no: 61) Development of transgenic fish: scientific background. Author(s): Nam, Y. K. Maclean, N. Fu, C. Pandian, T. J. Eguia, M. R. R.
Chapter: 4 (Page no: 95) Gene construct and expression: information relevant for risk assessment and management. Author(s): Gong, Z. Maclean, N. Devlin, R. H. Martinez, R. Omitogun, O. Estrada, M. P.
Chapter: 6 (Page no: 151) Assessing ecological effects of transgenic fish prior to entry into nature. Author(s): Devlin, R. H. Sundström, L. F. Johnsson, J. I. Fleming, I. A. Hayes, K. R. Ojwang, W. O. Bambaradeniya, C. Zakaraia-Ismail, M.
Chapter: 7 (Page no: 188) Introduction to the concepts and methods of uncertainty analysis. Author(s): Hayes, K. R. Regan, H. M. Burgman, M. A.
Chapter: 8 (Page no: 209) Risk management: reducing risk through confinement of transgenic fish. Author(s): Mair, G. C. Nam, Y. K. Solar, I. I.
Chapter: 9 (Page no: 239) Risk management: post-approval monitoring and remediation. Author(s): Senanan, W. Hard, J. J. Alcivar-Warren, A. Trisak, J. Zakaraia-Ismail, M. Lorenzo Hernandez, M.
Chapter: 10 (Page no: 272) Risk assessment of transgenic fish: synthesis and conclusions. Author(s): Kapuscinski, A. R. Dana, G. Hayes, K. R. Li, S. Nelson, K. C. Nam, Y. K. Gong, Z. Devlin, R. H. Mair, G. C. Senanan, W.